Results 201 to 210 of about 720,622 (316)

Targeting KMT5C Suppresses Lung Cancer Progression and Enhances the Efficacy of Immunotherapy

Advanced Science, EarlyView.
This study reveals that KMT5C activates DNA damage repair to inhibit STING‐IRF3 pathway, downstream type I IFN signaling and CCL5 secretion, leading to the downregulation of CD8+ T cell infiltration and function in NSCLC, ultimately facilitating tumor progression.
Yunfeng Yuan, Qianyu Li, Guoquan Yan, Yifei Qian, Wenyun Guo, Songling Li, Fan Wang, Wanjing Shang, Zijun Zhu, Di Ge, Yanan Wang, Yanfeng Liu   +11 more
wiley   +1 more source

TUMORS WHICH MAY EXPAND THE CURVATURE OF THE DUODENUM, PARTICUIARLY TUMORS AND INFECTIONS OF THE RETROPERITONEAL LYMPH NODES

, 1929
Clarence E. Bird
openalex   +2 more sources

Bioprinted Patient‐Derived Organoid Arrays Capture Intrinsic and Extrinsic Tumor Features for Advanced Personalized Medicine

Advanced Science, EarlyView.
An embedded bioprinting enabled‐arrayed patient‐derived organoids (Eba‐PDO) platform that replicates intrinsic and extrinsic tumor characteristics is introduced. Eba‐PDOs more accurately mimic tissue than standard PDOs (Std‐PDOs) due to maturation in the tumor microenvironment.
Jonghyeuk Han, Hye‐Jin Jeong, Jeonghan Choi, Hyeonseo Kim, Taejoon Kwon, Kyungjae Myung, Kyemyung Park, Jung In Park, Samuel Sánchez, Deok‐Beom Jung, Chang Sik Yu, In Ho Song, Jin‐Hyung Shim, Seung‐Jae Myung, Hyun‐Wook Kang, Tae‐Eun Park   +15 more
wiley   +1 more source

Mediastinal staging lymph node probability map in non-small cell lung cancer. [PDF]

Respir Res
Bordas-Martinez J, Vercher-Conejero JL, Rodriguez-González G, Notta PC, Martin Cabeza C, Cubero N, Lopez-Lisbona RM, Diez-Ferrer M, Tebé C, Santos S, Cortes-Romera M, Rosell A.   +11 more
europepmc   +1 more source

CLAMP METHOD TO OBTAIN CUTANEOUS LYMPH IN THE DIAGNOSIS OF LEPROSY

, 1947
H. C. de Souza-Araújo
openalex   +1 more source

RNF112 Facilitates Ubiquitin‐Mediated Degradation of c‐Myc, Suppressing Proliferation, Migration and Lipid Synthesis in Bladder Cancer

Advanced Science, EarlyView.
RNF112, an E3 ubiquitin ligase, is markedly reduced in bladder cancer (BLCA). It curbs BLCA cell proliferation, migration, and lipid production primarily by enhancing ubiquitin‐dependent degradation of c‐Myc. This degradation inhibits c‐Myc's role in upregulating ACLY, a crucial enzyme for lipid synthesis, highlighting RNF112's potential as a ...
Kangping Xiong, Siming Chen, Huimin Xu, Sheng Tu, Hong Weng, Yejinpeng Wang, Mingxing Li, Jingtian Yu, Kaiyu Qian, Lingao Ju, Yi Zhang, Yu Xiao, Xinghuan Wang, Gang Wang   +13 more
wiley   +1 more source

A rare case of Castleman disease presented with diffuse ground glass nodules in both lungs: Case report. [PDF]

Medicine (Baltimore)
Guo X, Zhu C, Zhang F, Chen J, Zhang K.
europepmc   +1 more source

PHASE MICROSCOPY STUDIES OF HODGKIN’S DISEASE LYMPH NODES IN RELATION TO HISTOGENESIS OF THE STERNBERG-REED CELL [PDF]

, 1950
G Hoffmann, Antonio Rottino
openalex   +1 more source

PCSK9 Promotes the Malignancy of Triple‐negative Breast Cancer Cells by Reducing Cholesterol Levels at the Plasma Membrane to Activate EGFR and HER3

Advanced Science, EarlyView.
By decreasing cholesterol and lipid raft levels in the plasma membrane, proprotein convertase subtilisin/kexin type 9 (PCSK9) boosts human epidermal growth factor receptor 1 and 3 (EGFR and HER3) activation, driving tumor growth and metastasis in triple‐negative breast cancer (TNBC).
Tianhong Li, Renfei Wu, Kathy Qian Luo
wiley   +1 more source

A multicentre prospective single-arm clinical trial to evaluate the treatment outcomes of prophylactic laparoscopic lateral pelvic lymph node dissection for advanced lower rectal cancer. [PDF]

Colorectal Dis
Hamabe A, Nishimura J, Suzuki Y, Yasui M, Ikenaga M, Tanida T, Yoshioka S, Ide Y, Takahashi Y, Takeyama H, Ogino T, Takahashi H, Miyoshi N, Fujii M, Ohno Y, Yamamoto H, Murata K, Uemura M, Doki Y, Eguchi H.   +19 more
europepmc   +1 more source