Results 71 to 80 of about 1,206,897 (338)

Elucidating prognostic significance of purine metabolism in colorectal cancer through integrating data from transcriptomic, immunohistochemical, and single‐cell RNA sequencing analysis

open access: yesMolecular Oncology, EarlyView.
Low expression of five purine metabolism‐related genes (ADSL, APRT, ADCY3, NME3, NME6) was correlated with poor survival in colorectal cancer. Immunohistochemistry analysis showed that low NME3 (early stage) and low ADSL/NME6 (late stage) levels were associated with high risk.
Sungyeon Kim   +8 more
wiley   +1 more source

Prevalence and Cause of Early Fontan Complications: Does the Lymphatic Circulation Play a Role?

open access: yesJournal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2020
Background Recent studies suggest that lymphatic congestion plays a role in development of late Fontan complications, such as protein‐losing enteropathy.
Reena M. Ghosh   +11 more
doaj   +1 more source

Lymph Node Reactivity. II. Fetal Lymph Nodes [PDF]

open access: yesBlood, 1959
Abstract A study was made of the progressive development of structure and metalophilia of the axillary nodes obtained from fetuses of various weights. Metalophil cells were rare in fetuses weighing less than 1000 Gm., while the adult pattern of metalophilia was not observed until the fetus approached 2000 Gm.
Maurice M. Black, Francis D. Speer
openaire   +3 more sources

Changes in the Cell Squad of Iliac Lymph Nodes of White Rats in Case of Longterm Influence of Nalbufin [PDF]

open access: yes, 2018
The article presents data on the change in the cellular composition of the lymph nodes of the white rats, males of reproductive age, who received intramuscular opioid analgesics - nalbuphine every day for six weeks.
Holovatskyi, A. (Andrew)   +1 more
core  

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

open access: yesMolecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau   +11 more
wiley   +1 more source

A serological investigation of caseous lymphadenitis in four flocks of sheep [PDF]

open access: yes, 2006
A double antibody sandwich ELISA developed by ID-DLO, Lelystad to detect Corynebocterium pseudotuberculosis infection was used on 329 sheep from four pedigree Suffolk flocks in which clinical cases of caseous lymphadenitis (CLA) had occurred.
Baird, Graham J.   +6 more
core   +6 more sources

Multi‐omic characterization of consensus molecular subtype 1 (CMS1) colorectal cancer with dampened immune response improves precision medicine

open access: yesMolecular Oncology, EarlyView.
This study highlights the importance of multi‐omic analyses in characterizing colorectal cancers. Indeed, our analysis revealed a rare CMS1 exhibiting dampened immune activation, including reduced PD‐1 expression, moderate CD8+ T‐cell infiltration, and suppressed JAK/STAT pathway.
Livia Concetti   +10 more
wiley   +1 more source

The effect of pancreatic diversion on lymphatic absorption and esterification of cholesterol in the rat

open access: yesJournal of Lipid Research, 1981
Lymph fistula rats with either biliary fistula or pancreaticobiliary fistula were used to measure coenzyme A-independent mucosal cholesterol esterifying activity in the presence and absence of pancreatic exocrine secretion.
S M Watt, W J Simmonds
doaj  

Experimental studies of the endolymphatic radiotherapy [PDF]

open access: yes, 1974
By injecting 131I-Lipiodol into lymphatics of the dorsum of dog feet, the distribution of 13JI in the lymph nodes and other principal organs as well as its histological effect were studied periodically after the injection for the period of two months ...
Irino, Shozo   +3 more
core   +1 more source

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

open access: yesMolecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani   +14 more
wiley   +1 more source

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