Results 181 to 190 of about 783,580 (401)

Cytological Classification Diagnosis for Thyroid Nodules via Multimodal Model Deep Learning

Advanced Science, EarlyView.
This study introduces AI‐TFNA, an innovative artificial intelligence model designed to assist cytopathologists in classifying thyroid nodules based on The Bethesda System for Reporting Thyroid Cytopathology (TBSRTC). The model effectively differentiates between benign and malignant thyroid nodules, demonstrating significant potential as a screening ...
Yuanzheng Lou, Yongjian Su, Haoda Lu, Wencai Li, Weihua Yin, Shengnan Li, Huobiao Zhu, Kok Haur Ong, Gang Chen, Yong Jiang, Yifei Liu, Shenglei Li, Manchun Yang, Zhengyu Zhang, Xiaoyan Wang, Xiaohui Zhu, Xinmi Huo, Longjie Li, Chao Wang, Nanyan Zhang, Weijun Pan, Bin Shang, Xudan Yang, Yongqiang Zhu, Xiaolin Liu, Weimiao Yu, Xiuwu Bian, Yanqing Ding   +27 more
wiley   +1 more source

Application of machine learning algorithm in prediction of lymph node metastasis in patients with intermediate and high-risk prostate cancer [PDF]

, 2023
xiangrong wang, xiangxiang zhang, Hengping Li, Mao Zhang, Yang Liu, Xuan-Peng Li   +5 more
openalex   +1 more source

rWTC‐MBTA Vaccine, Alone and Enhanced with Anti‐PD1, Elicits Immune Responses against CNS and Peripheral B‐Cell Lymphoma

Advanced Science, EarlyView.
An autologous whole‐tumor‐cell vaccine (rWTC‐MBTA) is evaluated in murine CNS lymphoma. Subcutaneous vaccination activates dendritic cells, broadens T‐cell priming, and drives lymphocyte trafficking to brain tumors, producing durable tumor control. Longitudinal bioluminescence and adoptive‐transfer assays verify CNS engagement. Combination with anti‐PD‐
Yaping Zhang, Juan Ye, Mitchell Sun, Samik Chakraborty, Alex Valenzuela, Shuran Chen, Qingfeng Xue, Wenyu Shi, Karel Pacak, Herui Wang, Zhengping Zhuang   +10 more
wiley   +1 more source

Red Blood Cell‐Derived Exosomal miR‐93‐5p Promotes Lung Cancer Progression through PTEN Suppression

Advanced Science, EarlyView.
Red blood cell (RBC)‐derived exosomal miR‐93‐5p is elevated in lung cancer patients and correlates with poor outcomes. Exosomal miR‐93‐5p suppresses PTEN in cancer cells, enhancing proliferation, migration, and invasion. In mouse models, therapeutic inhibition with ASO‐miR‐93 5p reduces tumor growth, highlighting a bidirectional tumor‐RBC‐tumor axis ...
Ning Li, Pushpa Dhilipkannah, Van K Holden, Ashutosh Sachdeva, Feng Jiang   +4 more
wiley   +1 more source

Lipid‐Driven OLR1/FOXM1/FGF19 Axis Orchestrates Crosstalk in an Epithelial‐Fibroblast Positive Feedback Promoting Progesterone Resistance in Endometrial Cancer

Advanced Science, EarlyView.
It is revealed that a metabolic–stromal loop driven by oxLDL–OLR1–FOXM1–FGF19 signaling promotes progesterone resistance in endometrial cancer. OxLDL activates epithelial–fibroblast crosstalk, enhancing proliferation and hormonal insensitivity. Disruption of this circuit, especially with resveratrol, restores MPA sensitivity, highlighting a potential ...
Xingchen Li, Yue Qi, Yuman Wu, Xinyi Bi, Yiqin Wang, Jiaqi Wang, Jingyuan Wang, Lingpu Zhang, Haihua Xiao, Jianliu Wang   +9 more
wiley   +1 more source

CypA Mediates Non‐Small Cell Lung Cancer Chemoresistance by Attenuating Ferroptosis via Stabilizing SLC7A11

Advanced Science, EarlyView.
Summary diagram for the role of CypA in chemoresistance in non‐small cell lung cancer (NSCLC). CypA is overexpressed in chemoresistance NSCLC and drives therapeutic evasion by competitively binding to the K37 site of SLC7A11, thereby blocking TRIM3 mediated K11‐linked ubiquitination and proteasomal degradation, ultimately inhibiting lipid peroxidation ...
Zhongcheng Wang, An Li, Ziwei Song, Xiangming Liu, Yong Ge, Zhiqiao Chen, Yuhui Liu, Boyu Zhang, Hao Zhang, Ting Lan   +9 more
wiley   +1 more source

Sequential Tumor Microenvironment Reprogramming by Nanoplatform Potentiates Sonodynamic‐Chemodynamic Therapy and Immune Checkpoint Blockade in Breast Cancer

Advanced Science, EarlyView.
A modular nanoplatform capable of sequentially reprogramming tumor microenvironment via cascade actions and responsive therapeutic functions is reported for breast cancer therapy. Via a dual‐targeting mechanism and responsive PD‐L1 antibody release, this nanoplatform enables amplified sonodynamic‐chemodynamic therapy and elicits robust immune response ...
Yang Yu, Zheming Song, Anni Zhu, Jingchao Li, Rujia Fan, Bing Xiao   +5 more
wiley   +1 more source

Correlation between the size of the breast lump and axillary lymph node metastasis in patients with carcinoma of breast.

, 2020
Sanjeeda Saad, SM Amjad Hossain, Majedul Islam   +2 more
openalex   +2 more sources

Usefulness of Narrow-band Imaging for Detecting the Primary Tumor Site in Patients with Primary Unknown Cervical Lymph Node Metastasis [PDF]

, 2010
Takayuki Hayashi, Manabu Muto, Ryuichi Hayashi, Keiko Minashi, Tomonori Yano, Shinji Kishimoto, Satoru Ebihara   +6 more
openalex   +1 more source

Concomittant occurence of well-differentiated thyroid carcinoma metastasis and chronic lymphocytic leukemia in the same lymph node along with internal jugular vein thrombus

, 2021
Havva Sezer, Dilek Yazıcı, Serdar Tezelman, Mehmet Onur Demirkol, Ömer F. Ünal, Şükrü Dilege, Orhun Ç Taşkın, Önder Peker, Yersu Kapran, Bülent Çolakoğlu, Murat S. Aygün, Burhan Ferhanoğlu, Faruk Alagöl   +12 more
openalex   +1 more source