Results 191 to 200 of about 346,670 (346)

Single‐Cell RNA Sequencing Identifies MMP11+ Cancer‐Associated Fibroblasts as Drivers of Angiogenesis and Bladder Cancer Progression

Advanced Science, EarlyView.
Single‐cell RNA sequencing identifies MMP11⁺ CAFs as pro‐angiogenic cells accumulating during bladder cancer progression. These cells promote angiogenesis by regulating ESM1⁺ tip endothelial cells and recruiting SPP1⁺ macrophages. Tumor‐derived BMP2 promotes their activation.
Wuwu Xu, Ting Liang, Hu Fang, Lu Fu, Dashi Deng, Xiyang Tan, Lisha Liu, Dongdong Tang, Haoxiang Zheng, Qiuxia Ding, Xiuqi Hou, Daquan Feng, Tao Tao, Song Wu   +13 more
wiley   +1 more source

Diagnosis of Mediastinal Lymph Node Metastasis from Primary Lung Cancer on MR Imaging with the STIR Technique. Reevaluation of Usefulness: Comparison with CT, Conventional MRI and MRI with the STIR Technique.

, 1994
Kiminori Fujimoto, S Meno, Toshi Abe, Osamu Edamitsu, Hiroshi Nishimura, Naofumi Hayabuchi, Shinzo Takamori, Akihiro Hayashi, Toru Rikimaru, Yoichiro Ichikawa   +9 more
openalex   +2 more sources

An Explainable Multimodal Artificial Intelligence Model Integrating Histopathological Microenvironment and EHR Phenotypes for Germline Genetic Testing in Breast Cancer

Advanced Science, EarlyView.
This study presents an explainable multimodal AI model, MAIGGT (Multimodal Artificial Intelligence Germline Genetic Testing), that combines whole‐slide histopathology with clinical data for accurate germline BRCA1/2 mutation prescreening. By integrating digital pathology and EHR phenotypes, MAIGCT enables cost‐effective, scalable hereditary breast ...
Zijian Yang, Changyuan Guo, Jiayi Li, Yalun Li, Lei Zhong, Pengming Pu, Tongxuan Shang, Lin Cong, Yongxin Zhou, Guangdong Qiao, Ziqi Jia, Hengyi Xu, Heng Cao, Yansong Huang, Tianyi Liu, Jian Liang, Jiang Wu, Dongxu Ma, Yuchen Liu, Ruijie Zhou, Xiang Wang, Jianming Ying, Meng Zhou, Jiaqi Liu   +23 more
wiley   +1 more source

Clinicopathological Characteristics of Colorectal Submucosal Carcinoma with Lymph Node Metastasis.

, 1993
YASUMI ARAKI, Hiroharu Isomoto, Kazuo Shirouzu, KAZUHIDE MIURA, Hiroki Iwanaga, Akira Okita, Teruo Sasatomi, Yutaka Ogata, T. Morodomi, Teruo Kakegawa   +9 more
openalex   +2 more sources

Mediastinal lymph node metastasis model by orthotopic intrapulmonary implantation of Lewis lung carcinoma cells in mice [PDF]

, 1999
Yoshinori Doki, Kazuhiro Murakami, T Yamaura, Shigeki Sugiyama, Takuro Misaki, I Saiki   +5 more
openalex   +1 more source

Advanced Cancer Immunotherapy via SMARCAL1 Blockade Using a Glucose‐Responsive CRISPR Nanovaccine

Advanced Science, EarlyView.
A glucose‐catalyzed chemodynamic strategy is proposed to activate therapeutic genome editing of SMARCAL1to improve cancer immunotherapy. This innovative design featuring Fenton reaction activity and glucose consumption ability, not only effectively synergizes to activate the cGAS‐STING pathway but also inhibits the opposing functions of interferon by ...
Yuwei Li, Yuanyi Zhang, Chenchen Li, Guoping Chen, Pir Muhammad, Yonghong Yao, Lifang Gao, Zhigang Liu, Yanli Wang   +8 more
wiley   +1 more source

Morphological predictors of lymph node metastasis in early gastric cancer. [PDF]

BMC Surg
Bozkurt HA, Ercan LD, Guden I, Buyuk M, Ilhan M, Gok AFK, Gunay MK.   +6 more
europepmc   +1 more source

Assessment of Cervical Lymph Node Metastasis in Esophageal Carcinoma Using Ultrasonography [PDF]

, 1999

openalex   +1 more source

Mitochondrial Regulation of CD8⁺ T Cells: Mechanisms and Therapeutic Modulation

Advanced Science, EarlyView.
This article comprehensively explores the pivotal role of mitochondrial function in CD8⁺ T cell immunotherapy. It highlights how mitochondrial dynamics regulate T cell activation, differentiation, and persistence, and how mitochondrial dysfunction leads to immune exhaustion and impaired antitumor/antiviral responses.
Xu Chen, Pei Lin, Ye Lu, Jiarong Zheng, Yunfan Lin, Zihao Zhou, Li Cui, Xinyuan Zhao   +7 more
wiley   +1 more source

The significance of lymph node metastasis in pT1-2 colorectal cancer. [PDF]

J Gastrointest Oncol
Song B, Wang L, Chen Y, Hirano Y.
europepmc   +1 more source