Results 141 to 150 of about 13,250 (289)

Case report: If it is not asthma—think of lymphangioleiomyomatosis in younger female patients

Frontiers in Medicine
Lymphangioleiomyomatosis (LAM) is a rare lung disease predominantly affecting women, and it is characterized by the proliferation of smooth muscle cells and cystic lung destruction.
Malene Helligsø Kirkeby, Elisabeth Bendstrup, Elisabeth Bendstrup, Hanne Krogh Rose   +3 more
doaj   +1 more source

Clinical Characteristics of Subependymal Giant Cell Astrocytoma in Tuberous Sclerosis Complex. [PDF]

, 2019
Background: This study evaluated the characteristics of subependymal giant cell astrocytoma (SEGA) in patients with tuberous sclerosis complex (TSC) entered into the TuberOus SClerosis registry to increase disease Awareness (TOSCA).
Agranovich, Oleg, Altunbasak, Sakir, Anlar, Banu, Belousova, Elena, Belyaev, Oleg Valeryevich, Benedik, Mirjana P., Carter, Tom, Cottin, Vincent, Curatolo, Paolo, D'Amato, Lisa, D'Augères, Guillaume Beaure, Dahlin, Maria, De Vries, Petrus J., Endo, Shoichi, Ferreira, José C., Feucht, Martha, Fladrowski, Carla, Hertzberg, Christoph, Horie, Shigeo, Imai, Katsumi, Inoue, Yoshikazu, Jansen, Anna C., Jozwiak, Sergiusz, Kaneda, Mari, Kaneko, Hideo, Kingswood, John C., Kirino, Tomoko, Kubota, Masaya, Lawson, John A., Levitina, Elena Vladislavovna, Lvova, Olga, Macaya, Alfons, Marques, Ruben, Nabbout, Rima, O'Callaghan, Finbar, Qin, Jiong, Sander, Valentin, Sauter, Matthias, Serdaroglu, Ayse, Shah, Seema, Shinohara, Nobuo, Takahashi, Yukitoshi, Tohyama, Jun, TOSCA Consortium and TOSCA Investigators, Touraine, Renaud, Uchida, Yasushi, Uruno, Katsuhisa, Yapici, Zuhal, Youroukos, Sotiris, Zonnenberg, Bernard   +49 more
core   +2 more sources

Repurposing Nitazoxanide for Potential Treatment of Rare Disease Lymphangioleiomyomatosis

Biomolecules
Lymphangioleiomyomatosis (LAM) is a rare genetic lung disease. Unfortunately, treatment with the mTORC1 inhibitor Rapamycin only slows disease progression, and incomplete responses are common.
Stella Bähr, Ryan W. Rue, Carly J. Smith, Jillian F. Evans, Hubert Köster, Vera P. Krymskaya, Dirk Pleimes   +6 more
doaj   +1 more source

The first lung transplantation at the Research Institute for Emergency named after N.V. Sklifosovsky

Трансплантология (Москва), 2018
The paper describes the first lung transplantation at the N.V. Sklifosovsky Research Institute of Emergency Care in a female patient with endstage pulmonary lymphangioleiomyomatosis, which has shown a good result during a 6-month follow-up.
M. Sh. Khubutia, A. G. Chuchalin, M. M. Abakumov, S. N. Avdeev, V. Kh. Timerbaev, I. V. Poplavsky, M. A. Godkov, M. G. Minina, E. A. Tarabrin, N. A. Karchevskaya, S. V. Golovinsky, N. N. Levitskaya, V. A. Gulyaev, N. N. Meshcheryakova, M. V. Samsonova, V. B. Polishchuk, D. F. Ibragimova, D. Kh. Tsurova, I. E. Selina, I. E. Popova   +19 more
doaj   +1 more source

The dual PI3K/mTOR inhibitor GSK2126458 is effective for treating solid renal tumours in Tsc2+/- mice through suppression of cell proliferation and induction of apoptosis [PDF]

, 2017
Tuberous sclerosis (TSC) is an inherited tumour syndrome caused by mutations in TSC1 or TSC2 that lead to aberrant activation of mTOR. Tumour responses in TSC patients to rapamycin, an allosteric inhibitor of mTOR, or its analogs are partial and ...
Jones, Ashley, Narov, Kalin, Sampson, Julian R, Samsel, Paulina, Shen, Ming Hong, Yang, Jian   +5 more
core   +1 more source

Determinants of Progression and Mortality in Lymphangioleiomyomatosis.

Chest, 2023
Wenshaui Xu, Chenlu Yang, Chongsheng Cheng, Yani Wang, Danjing Hu, Jiannan Huang, Yudi He, Jun Wang, Keqi Chen, Lu Yang, Wangji Zhou, Tengyue Zhang, Song Liu, J. Dai, S. Meng, Xue Li, Yanli Yang, Shao-Ting Wang, R. Feng, Weihong Zhang, Hongbing Zhang, Li Wang, X. Tian, Kaifeng Xu   +23 more
semanticscholar   +1 more source

Complications of lymphangioleiomyomatosis in pregnancy: a case report and review of the literature

AJOG Global Reports
Lymphangioleiomyomatosis is a rare cystic lung disease primarily affecting premenopausal females and may be exacerbated by pregnancy. We conducted a literature review of lymphangioleiomyomatosis during pregnancy with a specific focus on related maternal ...
Eileen Wang-Koehler, MD, Adina R. Kern-Goldberger, MD, MPH, MSCE, Sindhu K. Srinivas, MD, MSCE   +2 more
doaj  

Recent advances in interstitial lung disease research [PDF]

, 2006
The interstitial lung diseases are a diverse collection of disorders characterized by impaired gas exchange, restricted physiology on lung function testing, and diffuse parenchymal lung infiltrates on radiography.
Vassallo, Robert
core  

Interstitial pneumonia with autoimmune features and undifferentiated connective tissue disease: Our interdisciplinary rheumatology-pneumology experience, and review of the literature [PDF]

, 2016
Background: Interstitial lung diseases (ILDs) are a heterogeneous group of disorders characterized by inflammation and/or fibrosis of the lungs, varying from idiopathic interstitial pneumonias to secondary variants, including the ILDs associated to ...
Cerri, Stefania, Colaci, Michele, Della Casa, Giovanni, Ferri, Clodoveo, Giuggioli, Dilia, Luppi, Fabrizio, Manfredi, Andreina, Sebastiani, Marco, Torricelli, Pietro, Vacchi, Caterina   +9 more
core   +1 more source

Pulmonary lymphangioleiomyomatosis in a male [PDF]

, 1991
Hyun Wook Kang, Chang Jin Kim, Sang Kook Lee, Kyung Soo Lee, Chul Sae Lee, Yong Hoon Kim   +5 more
openalex   +1 more source