Results 91 to 100 of about 419,246 (294)

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Protein Tyrosine Phosphatase 4A1 (PTP4A1) Regulates Early Events in Colorectal Cancer Intraperitoneal Dissemination in the Aged Male Host

Aging and Cancer, EarlyView.
Colorectal cancer (CRC) mortality is highest in aged males. Pre‐clinical data comparing CRC i.p. metastasis in cohorts of young and aged, male and female mice support these finding. Bottom‐up proteomics of peritoneal mesothelial cells identified PTP4A1 as highly expressed in aged males and a role for PTP4A1 in heterotypic cell:cell adhesion was ...
Zhikun Wang, Yueying Liu, Jing Yang, Tyvette S. Hilliard, Reihaneh Safavi‐Sohi, Daniel D. Hu, Elizabeth I. Harper, Gena Dominique, Wanrui Wang, Jeffrey Johnson, Marwa Asem, William Milosevich, Julia Florek Carlson, Yunpeng Bai, Jinmin Miao, Zhong‐Yin Zhang, Matthew M. Champion, M. Sharon Stack   +17 more
wiley   +1 more source

Canal of Nuck cyst: surgical management and lymphatic preservation in three cases

Veins and Lymphatics
The canal of Nuck cyst is a rare but clinically relevant pathology, often mistaken for inguinal hernias or other soft tissue anomalies. It results from the incomplete obliteration of the processus vaginalis during fetal development.
C. Eretta, F. Di Pumpo, C. Bianchi, N. Gorji, M. Moroni, C. Feleppa   +5 more
doaj   +1 more source

A Multi‐Center Retrospective Cohort Study of Neurosarcoidosis Myelitis: Current Observations and Future Directions

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The optimal treatment for neurosarcoidosis myelitis is uncertain. We characterize incident neurosarcoidosis myelitis and assess treatment response by MRI and clinical scales. Methods Incident probable or definite neurosarcoidosis myelitis in adults was retrospectively identified from 13 academic medical centers.
Giovanna S. Manzano, Denis Balaban, Yihan Zhang, Brian Healy, Bart K. Chwalisz, Michael Levy, Nagagopal Venna, Barney J. Stern, Carlos A. Pardo, Paula Barreras, Nicole Bou Rjeily, Eoin P. Flanagan, Vyanka Redenbaugh, Allen J. Aksamit Jr., Spencer Hutto, Max Herman, Sally El Sammak, Elsa C. Rodriguez, Laura Snider, Hannah Rains, Mayra Montalvo, Torge Rempe, Sergi Martinez Ramirez, Lucas Horta, Stacey Clardy, Jennifer Lord, Tracey A. Cho, Lama Abdel Wahed, Joseph R. Berger, Rohini D. Samudralwar, Noellie Rivera Torres, David B. Clifford, Steven Richard Dunham, Masoud Majed, Aram Zabeti, Samuel Marcucci, Yang Mao‐Draayer, Jon Doty, Paunel B. Agyei, Shamik Bhattacharyya   +39 more
wiley   +1 more source

Case Report: Lymphangiogram and embolization for malignant chylothorax in cancer patients

Frontiers in Oncology
Tumor-related lymphatic obstruction can cause malignant chylothorax, which can be debilitating. Conventional management includes dietary modifications, percutaneous drainage, and medical management (octreotide), most of which prove refractory in high ...
John T. Moon, Hanzhou Li, Omar Abdalla, Nicholas Swilley   +3 more
doaj   +1 more source

Neurotrophic keratitis in a patient with disseminated lymphangiomatosis. [PDF]

, 2009
INTRODUCTION: Neurotrophic keratitis, a degenerative corneal disease caused by trigeminal nerve impairment, has many etiologies and remains very difficult to treat.
Charukamnoetkanok, Puwat, Knickelbein, Jared E, Stefko, Susan T   +2 more
core   +2 more sources

Update on the current knowledge of lymphatic drainage system and its emerging roles in glioma management [PDF]

, 2022
Yu‐Long Lan, Hongjin Wang, Aiqin Chen, Jianmin Zhang   +3 more
openalex   +1 more source

RRP9 Promotes Esophageal Squamous Cell Carcinoma Progression through E2F1 Transcriptional Regulation of CDK1

Advanced Biology, EarlyView.
The study reveals that RRP9 is abnormally highly expressed in ESCC tissues and is closely associated with poor prognosis in patients. Furthermore, it is found that RRP9 promotes ESCC progression through enhancing the E2F1‐mediated transcriptional regulation of CDK1.
Gang He, Yilong Wan, Yanbo Zhu, Bo Peng, Shengxiang Shao, Xinyi Zou, Zhenyu Han, Jiaxi Li, Sheng Ju, Xin Tong, Jun Zhao, Hansi Liang, Liuqing Zhang, Jiashi Xiong, Dong Jiang   +14 more
wiley   +1 more source

Correction to: Liposuction in cancer-related lower extremity lymphedema: an investigative study on clinical applications

World Journal of Surgical Oncology, 2022
Jianfeng Xin, Yuguang Sun, Song Xia, Kun Chang, Chao Dong, Zhong Liu, Jian Dong, Wenbin Shen   +7 more
doaj   +1 more source

Use of digital assessment tools to measure health facility readiness to provide the WHO recommended package of care for lymphatic filariasis morbidity

Frontiers in Tropical Diseases
BackgroundA country claiming to have achieved elimination of Lymphatic filariasis (LF) as a public health problem must undergo and document a quality assessment of the World Health Organization (WHO) recommended essential package of care for patients ...
Windtaré Roland Bougma, Victorino Martinho Aiogalé, Bienvenu Yao Attoumbre, Sarah Bartlett, Kouma Brahima, Mamadou Coulibaly, Yaya Ibrahim Coulibaly, Boubacar Morou Dicko, Susan D’Souza, Salif Seriba Doumbia, Gar Mondyu Gargannah, Balla Musa, Babacar Ngom, Dje N’Goran Norbert, Christian Nwosu, Alberto Luis Papique, Emerson J. Rogers, Astou Sarr, Philip Downs   +18 more
doaj   +1 more source