Results 91 to 100 of about 512,900 (381)

Change in Composition of the Anopheles Gambiae Complex and its Possible Implications for the Transmission of Malaria and Lymphatic Filariasis in North-Eastern Tanzania. [PDF]

, 2012
A dramatic decline in the incidence of malaria due to Plasmodium falciparum infection in coastal East Africa has recently been reported to be paralleled (or even preceded) by an equally dramatic decline in malaria vector density, despite absence of ...
A Mahande, AE Mnzava, AEP Mnzava, AJ van Rensburg, BA Southgate, BP Mmbando, C Garrett-Jones, C Garrett-Jones, CA Johansen, CJ Shiff, CM Mbogo, CM Mutero, CNM Mbogo, Dan W Meyrowitsch, DW Meyrowitsch, EA Temu, Erling M Pedersen, ESP Kigadye, FH Collins, FM Bushrod, FM Bushrod, FW Mosha, G Davidson, G Snounou, GB White, GB White, GB White, H Bugoro, I Tirados, JA Scott, JD Lines, JE McMahon, KA Lindblade, Kenneth M Hosea, LL Koekemoer, M Coluzzi, Michael Alifrangis, MN Bayoh, MT Gillies, MT Gillies, Paul E Simonsen, PE Simonsen, RH Hunt, RT Rwegoshora, SA Williams, SM Magesa, Stephen M Magesa, T Jaenisch, TL Russell, V D’Acremont, World Health Organization, WP O’Meara, Yahya A Derua   +52 more
core   +4 more sources

Cell‐free DNA aneuploidy score as a dynamic early response marker in prostate cancer

Molecular Oncology, EarlyView.
mFast‐SeqS‐based genome‐wide aneuploidy scores are concordant with aneuploidy scores obtained by whole genome sequencing from tumor tissue and can predict response to ARSI treatment at baseline and, at an early time point, to ARSI and taxanes. This assay can be easily performed at low cost and requires little input of cfDNA. Cell‐free circulating tumor
Khrystany T. Isebia, Anouk C. de Jong, Lisanne F. van Dessel, Vanja de Weerd, Corine Beaufort, Jean Helmijr, José Alberto Nakauma‐González, Job van Riet, Paul Hamberg, Daniel Vis, Michiel S. van der Heijden, Nick Beije, Martijn P. Lolkema, Teoman Deger, Saskia M. Wilting, Ronald de Wit, Maurice P. H. M. Jansen, John W. M. Martens   +17 more
wiley   +1 more source

Development and plasticity of meningeal lymphatic vessels

Journal of Experimental Medicine, 2017
The recent discovery of meningeal lymphatic vessels (LVs) has raised interest in their possible involvement in neuropathological processes, yet little is known about their development or maintenance.
Salli Antila, Sinem Karaman, H. Nurmi, M. Airavaara, M. Voutilainen, T. Mathivet, D. Chilov, Zhilin Li, Tapani Koppinen, Jun-Hee Park, Shentong Fang, Aleksanteri Aspelund, M. Saarma, A. Eichmann, Jean-Léon Thomas, K. Alitalo   +15 more
semanticscholar   +1 more source

Structure and age-dependent development of the turkey liver: a comparative study of a highly selected meat-type and a wild-type turkey line [PDF]

, 2019
In this study the macroscopic and microscopic structure of the liver of a fast growing, meat-type turkey line (British United turkeys BUT Big 6, n = 25) and a wild-type turkey line (Wild Canadian turkey, n = 48) were compared at the age of 4, 8, 12, 16 ...
Custodis, Pia, Gemeinhardt, Ole, Hafez, Hafez Mohamed, Hirschberg, Ruth M., Hünigen, Hana, Mainzer, Kathleen, Masri, Salah Al, Plendl, Johanna, Richardson, Kenneth C.   +8 more
core   +1 more source

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

Molecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau, Hayley S. Smith, Begüm Alural, Claire E. Martin, Laura A. New, Manali Tilak, Sara L. Banerjee, Hannah N. Robeson, Nicolas Bisson, Anne‐Claude Gingras, Jasmin Lalonde, Nina Jones   +11 more
wiley   +1 more source

Cerebrovascular Smooth Muscle Cells as the Drivers of Intramural Periarterial Drainage of the Brain

Frontiers in Aging Neuroscience, 2019
The human brain is the organ with the highest metabolic activity but it lacks a traditional lymphatic system responsible for clearing waste products.
Roxana Aldea, Roy O. Weller, Donna M. Wilcock, Roxana O. Carare, Giles Richardson   +4 more
doaj   +1 more source

LYMPHATIC VARICOCELE. [PDF]

The Lancet, 1912
n ...
openaire   +2 more sources

Organ-specific lymphatic vasculature: From development to pathophysiology

Journal of Experimental Medicine, 2018
Petrova and Koh discuss recent progress in understanding organ-specific specialization of lymphatic vasculature, such as discovery of meningeal lymphatic vasculature and perivascular brain lymphatic endothelial cells, hybrid blood-lymphatic identity of ...
T. Petrova, G. Koh
semanticscholar   +1 more source

CLEC-2 and Syk in the megakaryocytic/platelet lineage are essential for development [PDF]

, 2011
The C-type lectin receptor CLEC-2 signals through a pathway that is critically dependent on the tyrosine kinase Syk. We show that homozygous loss of either protein results in defects in brain vascular and lymphatic development, lung inflation and ...
Abramoff, Abtahian, Alice Y. Pollitt, Aparicio-Vergara, Bertozzi, Bohmer, Brenda A. Finney, Caetano Reis e Sousa, Carramolino, Caton, Cecile Bénézech, Chagraoui, Cheng, Christou, Clausen, Colonna, Craig E. Hughes, Cueni, de Boer, Diego Mourao-Sa, Edina Schweighoffer, Francesca Barone, Gerard B. Nash, Gustafsson, Hodivala-Dilke, Hughes, Hughes, Humphreys, Ichise, Kate L. Lowe, Kaufmann, Kerrigan, Leyre Navarro-Núñez, Makinen, Martin-Villar, May, Mocsai, Mourao-Sa, Navarro, Navarro, Nicholas Smithers, Nieswandt, Pardridge, Ramirez, Saijo, Schacht, Sebzda, Spalton, Stacey A. Langan, Steve P. Watson, Steve Sheardown, Suzuki-Inoue, Suzuki-Inoue, Suzuki-Inoue, Suzuki-Inoue, Tammela, Tang, Tiedt, Tober, Turner, Uhrin, Victor L. J. Tybulewicz, Warburton, Watson, Williams, Xie, Xu   +66 more
core   +2 more sources

Multi‐omic characterization of consensus molecular subtype 1 (CMS1) colorectal cancer with dampened immune response improves precision medicine

Molecular Oncology, EarlyView.
This study highlights the importance of multi‐omic analyses in characterizing colorectal cancers. Indeed, our analysis revealed a rare CMS1 exhibiting dampened immune activation, including reduced PD‐1 expression, moderate CD8+ T‐cell infiltration, and suppressed JAK/STAT pathway.
Livia Concetti, Manuel Scimeca, Julia Bischof, Jonathan Woodsmith, Massimiliano Agostini, Cristina Fiorani, Yufang Shi, Eleonora Candi, Gerry Melino, Alessandro Mauriello, Giuseppe S. Sica   +10 more
wiley   +1 more source