Results 101 to 110 of about 512,900 (381)

From Mechanisms to Treatment: A Comprehensive View of Lymphatic Metastasis in Cancer

Lymphatics
The lymphatic system, a complex and dynamic network comprising lymphatic vessels, lymph nodes (LNs), and associated lymphoid tissues, plays a pivotal role in regulating interstitial fluid balance and providing immune surveillance across the body.
Nitya Devisetti, Pushti Shah, Farrah C. Liu   +2 more
doaj   +1 more source

A Tumor‐on‐a‐Chip System with Bioprinted Blood and Lymphatic Vessel Pair

Advanced Functional Materials, 2019
Current in vitro antitumor drug screening strategies insufficiently mimic biological systems. They tend to lack true perfusion and draining microcirculation systems, which may post significant limitations in explicitly reproducing the transport kinetics ...
Xia Cao, Ramla Ashfaq, Feng Cheng, S. Maharjan, Jun Li, G. Ying, Shabir Hassan, Haiyan Xiao, K. Yue, Y. S. Zhang   +9 more
semanticscholar   +1 more source

Lymphatic Endothelial Cell Junctions: Molecular Regulation in Physiology and Diseases

Frontiers in Physiology, 2020
Lymphatic endothelial cells (LECs) lining lymphatic vessels develop specialized cell-cell junctions that are crucial for the maintenance of vessel integrity and proper lymphatic vascular functions.
Feng Zhang, G. Zarkada, Sanjun Yi, A. Eichmann   +3 more
semanticscholar   +1 more source

The burden of neglected tropical diseases in Ethiopia, and opportunities for integrated control and elimination [PDF]

, 2012
Background: Neglected tropical diseases (NTDs) are a group of chronic parasitic diseases and related conditions that are the most common diseases among the 2·7 billion people globally living on less than US$2 per day.
A Alemu, A Aseffa, A Deressa, A Haileamlak, A Yami, Abraham Aseffa, AD Bryceson, Ahmed Ali, AM Dorkenoo, Asrat Hailu, AZ Zein, B Erko, B Erko, B Liese, B Yakob, BA Boatin, C Bogh, C Hanson, C Prasittisuk, C Sikorski, Central Statistical Agency [Ethiopia], ICF International, D Fekadu, DG Addiss, DH Molyneux, DH Molyneux, DR ten Eyck, E Litt, E Negera, E Negera, E Ruiz-Tiben, E Yimer, EW Price, F Demissie, F Tekola, FMOH, FMOH, FMoH, G Davey, G Davey, G Davey, G Mengistu, G Tefera, Gail Davey, GS Smith, H Birrie, H Kloos, H Kloos, J Alvar, J Alvar, JH Kolaczinski, JH Kolaczinski, JO Gyapong, K Bogel, KA Grépin, Kadu Meribo, Kebede Deribe, L Erosie, L Jemaneh, M Fekadu, M Fekadu, M Herrero, MA Brady, MC Baker, Ministry of Health, MJ Burton, MJ Taylor, N Kebede, NB Kabatereine, P Steinmann, PJ Hotez, PJ Hotez, PJ Hotez, PJ Hotez, PJ Hotez, PM Emerson, R ter Horst, RL Pullan, RW Ashford, S Bashaye, S Brooker, S Brooker, S Cairncross, S Negash, SG Gundersen, T Wondimagegnehu, Teshome Gebre, The Carter Center, W Shiferaw, WHO, WHO, WHO, WHO, WHO, WHO, WHO, WHO, WHO, WHO, WHO, WHO, WHO, Y Berhane, Z Tadesse, ZA Zein   +103 more
core   +2 more sources

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

Molecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani, Gilgi Friedlander, Gili Perry, Nora Balint‐Lahat, Shlomit Gilad, Dana Morzaev‐Sulzbach, Anjana Shenoy, Noa Bossel Ben‐Moshe, Anya Pavlovsky, Rinat Bernstein‐Molho, Eytan Domany, Iris Barshack, Tamar Geiger, Bella Kaufman, Einav Nili Gal‐Yam   +14 more
wiley   +1 more source

A comparison of lymphatic embolization and sclerotherapy in the management of iatrogenic abdominopelvic lymphoceles following oncological surgery

Diagnostic and Interventional Radiology, 2023
PURPOSETo compare the safety and efficacy of sclerotherapy and lymphatic embolization (LE) in the treatment of symptomatic iatrogenic lymphoceles following the placement of a percutaneous drainage catheter.METHODSThis is a retrospective study of 46 ...
Amgad M. Moussa, Ahmed K. Aly, Majid Maybody, Juan C. Camacho, Fourat Ridouani, Adrian J. Gonzalez-Aguirre, Ernesto Santos   +6 more
doaj   +1 more source

Deregulation of HDAC5 by Viral Interferon Regulatory Factor 3 Plays an Essential Role in Kaposi's Sarcoma-Associated Herpesvirus-Induced Lymphangiogenesis. [PDF]

, 2018
Kaposi's sarcoma-associated herpesvirus (KSHV) is the etiologic agent for Kaposi's sarcoma (KS), which is one of the most common HIV-associated neoplasms.
Fan Li, Grace M. Aldrovandi, Hye Ryun Yu, Hye-Ra Lee, Jae U. Jung, Peter Palese, Pinghui Feng, Shou-Jiang Gao, Un Yung Choi, Young-Kwon Hong   +9 more
core   +3 more sources

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

Molecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu, Katherine Eason, Suet‐Feung Chin, Paul A. W. Edwards, Raquel Manzano Garcia, Richard Moulange, Jia Wern Pan, Soo Hwang Teo, Sach Mukherjee, Maurizio Callari, Carlos Caldas, Stephen‐John Sammut, Oscar M. Rueda   +12 more
wiley   +1 more source

Application of indocyanine green lymphography in the diagnosis and treatment of secondary upper extremity lymphedema: a systematic review

Journal of Plastic Surgery and Hand Surgery
Background: Lymphedema is a chronic progressive disease that impairs patients’ physical and psychological health. This study aimed to conduct a systematic review of the application of indocyanine green (ICG) lymphography for the diagnosis and treatment ...
Youlei Qian, Zixuan Yao, Chao Wang, Chao Dong, Song Xia, Yuguang Sun, Wenbin Shen, Jianfeng Xin   +7 more
doaj   +1 more source

Intestinal Lymph Flow, and Lipid and Drug Transport Scale Allometrically From Pre-clinical Species to Humans

Frontiers in Physiology, 2020
The intestinal lymphatic system transports fluid, immune cells, dietary lipids, and highly lipophilic drugs from the intestine to the systemic circulation.
Natalie L. Trevaskis, Given Lee, Given Lee, Given Lee, Alistair Escott, Alistair Escott, Kian Liun Phang, Kian Liun Phang, Jiwon Hong, Enyuan Cao, Enyuan Cao, Kasiram Katneni, Susan A. Charman, Sifei Han, Sifei Han, William N. Charman, Anthony R. J. Phillips, Anthony R. J. Phillips, John A. Windsor, John A. Windsor, Christopher J. H. Porter, Christopher J. H. Porter   +21 more
doaj   +1 more source