Results 131 to 140 of about 419,246 (294)
Novel mutation in CCBE 1 as a cause of recurrent hydrops fetalis from Hennekam lymphangiectasia-lymphedema syndrome-1. [PDF]
, 2018 Whole exome sequencing (WES) was used to determine the etiology of recurrent hydrops fetalis in this case of Hennekam lymphangiectasia-lymphedema syndrome-1.
Andreasen, Tara S +7 more
core
Advanced Healthcare Materials, EarlyView.Bioengineering tumor‐stroma pancreatic cancer models with potential to emulate the native immunosuppressive tumor microenvironment. Cancer‐on‐a‐bead models exhibited higher relevance for screening immunotherapies and modulating the protumoral PDAC microenvironment. ABSTRACT Pancreatic cancer is notably resistant to treatment, primarily due to its dense
Maria V. Monteiro +4 more
wiley +1 more source
Advanced Healthcare Materials, EarlyView.A novel method that combines 3D printing and organ‐on‐chip technology enables the creation of hollow channels lined with endothelial cells through a fibroblast‐populated connective tissue matrix. The model supports stable metabolic culture conditions, angiogenic sprouting, and immune cell migration, thereby demonstrating an easy and versatile method to
Jonas Jäger +7 more
wiley +1 more source
Hypoxia Increases Breast Cancer Cell-Induced Lymphatic Endothelial Cell Migration
, 2008 Maria Mikhaylova +5 more
openalex +1 more source
Engineering Complexity: Advances in 3D Breast Cancer Models for Precision Oncology
Advanced Healthcare Materials, EarlyView.In vitro breast cancer models that closely mimic the complex biological and cellular interactions within the tumor microenvironment hold strong promise for enhancing our understanding of tumor progression, immune system behavior, and resistance to therapies, which are essential for developing personalized cancer treatments. Abstract Engineered in vitro
Wonwoo Jeong, Sang Jin Lee
wiley +1 more source
Microphysiological Systems of Lymphatics and Immune Organs
Advanced Healthcare Materials, EarlyView.This review surveys recent progress in engineering lymphatic microenvironments and immune organoids within microphysiological systems, emphasizing innovative strategies to recreate the biochemical and biophysical complexity of native lymphatic tissues.
Ishita Jain +2 more
wiley +1 more source
Enhanced Delivery of Rituximab Into Brain and Lymph Nodes Using Timed-Release Nanocapsules in Non-Human Primates. [PDF]
, 2019 Tumor metastasis into the central nervous system (CNS) and lymph nodes (LNs) is a major obstacle for effective therapies. Therapeutic monoclonal antibodies (mAb) have revolutionized tumor treatment; however, their efficacy for treating metastatic tumors ...
Chen, Irvin SY +18 more
core +1 more source
An important role of lymphatic vessel activation in limiting acute inflammation [PDF]
, 2011 Reto Huggenberger +8 more
openalex +1 more source
Synthetic Cell‐Based Tissues for Bottom‐Up Assembly of Artificial Lymphatic Organs
Advanced Healthcare Materials, EarlyView.Synthetic cells have emerged as a novel biomimetic approach for fundamental research and therapeutic interventions. T cell activating synthetic cells are able to form 3D tissue‐like structures by self‐assembly into lymphatic bottom‐up tissues (lymphBUT) with tunable biochemical and biomechanical functionalities as well as metabolic activity are ...
Anna Burgstaller +5 more
wiley +1 more source