Results 151 to 160 of about 512,900 (381)
Bilateral lower extremity inflammatory lymphedema after an ultramarathon
William H. Robinson, DO+2 more
doaj +1 more source
Tumor-Associated Lymphatic Vessel Features and Immunomodulatory Functions
The lymphatic system comprises a network of lymphoid tissues and vessels that drains the extracellular compartment of most tissues. During tumor development, lymphatic endothelial cells (LECs) substantially expand in response to VEGFR-3 engagement by ...
L. Garnier, A. Gkountidi, S. Hugues
semanticscholar +1 more source
The tumor microenvironment is a dynamic, multifaceted complex system of interdependent cellular, biochemical, and biophysical components. Three‐dimensional in vitro models of the tumor microenvironment enable a better understanding of these interactions and their impact on cancer progression and therapeutic resistance.
Salma T. Rafik+3 more
wiley +1 more source
Hunterian Lectures ON THE SURGERY OF THE LYMPHATIC SYSTEM [PDF]
W. S. Handley
openalex +1 more source
IFNγ-activated dermal lymphatic vessels inhibit cytotoxic T cells in melanoma and inflamed skin
Mechanisms of immune suppression in peripheral tissues counteract protective immunity to prevent immunopathology and are coopted by tumors for immune evasion.
Ryan S Lane+9 more
semanticscholar +1 more source
Elephantiasis nostras verrucosa: an atypical presentation following intrapelvic lymphoma [PDF]
Elephantiasis nostras verrucosa is a progressively debilitating and disfiguring disease commonly presenting with verrucous, cobblestone-like papules, nodules, or plaques with nonpitting edema in the lower extremities.
Dahle, Sara E+3 more
core
Current trends in single‐cell RNA sequencing applications in diabetes mellitus
Single‐cell RNA sequencing is a powerful approach to decipher the cellular and molecular landscape at a single‐cell resolution. The rapid development of this technology has led to a wide range of applications, including the detection of cellular and molecular mechanisms and the identification and introduction of novel potential diagnostic and ...
Seyed Sajjad Zadian+6 more
wiley +1 more source
Ro 31‐8220 suppresses bladder cancer progression via enhancing autophagy in vitro and in vivo
The pan‐protein kinase C inhibitor Ro‐31‐8220 demonstrates potent anti‐bladder cancer effects both in vitro and in vivo by suppressing migration/invasion, inducing apoptosis and crucially activating autophagy, where blocking autophagy with chloroquine reduces its cell‐killing efficacy, suggesting its promise as a novel therapeutic candidate requiring ...
Shengjun Fu+12 more
wiley +1 more source
Case Report: Lymphangiogram and embolization for malignant chylothorax in cancer patients
Tumor-related lymphatic obstruction can cause malignant chylothorax, which can be debilitating. Conventional management includes dietary modifications, percutaneous drainage, and medical management (octreotide), most of which prove refractory in high ...
John T. Moon+3 more
doaj +1 more source