Results 161 to 170 of about 512,900 (381)
High LRIG1 expression predicts lymph node metastasis in patients with uterine cervical cancer
FEBS Open Bio, EarlyView.Lymph node status is crucial in determining treatment for women with early‐stage cervical cancer. We demonstrate that high LRIG1 protein expression in primary tumors can predict lymph node metastases. Our findings support further investigation of LRIG1 as a biomarker to improve staging accuracy and guide treatment decisions in cervical cancer patients.
Pernilla Israelsson +5 more
wiley +1 more source
VEGF-C-driven lymphatic drainage enables immunosurveillance of brain tumours
Nature, 2020 E. Song +8 more
semanticscholar +1 more source
Key role for inhibins in effective T cell activation, migration and Th17 differentiation
FEBS Open Bio, EarlyView.Activins/inhibins modulate immune responses. Here, we show that inhibins can be produced very early after T cell activation and can act in an autocrine way, favoring Th1 versus Th17 differentiation and CCL19/CCL21 mediated migration. Recombinant inhibin A can restore the Th1/Th17 balance, highlighting the role of inhibins as key regulators of T cell ...
Sandra Ortega‐Francisco +5 more
wiley +1 more source
Canal of Nuck cyst: surgical management and lymphatic preservation in three cases
Veins and LymphaticsThe canal of Nuck cyst is a rare but clinically relevant pathology, often mistaken for inguinal hernias or other soft tissue anomalies. It results from the incomplete obliteration of the processus vaginalis during fetal development.
C. Eretta +5 more
doaj +1 more source
FEBS Open Bio, EarlyView.We propose a context‐dependent model where the Duchenne muscular dystrophy (DMD) gene acts as a tumour suppressor in aggressive tumours and as an oncogene in less aggressive ones. We propose this model as a unified framework to explain the opposing survival associations with DMD expression and to guide experimental exploration of the dual role of DMD ...
Lee Machado +4 more
wiley +1 more source
A Case of Acute Lymphatic Leukemia in an Infant [PDF]
, 1905 Ralph C. Larrabee
openalex +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Sphingosine‐1‐phosphate receptor modulators (S1PRM) are used to treat relapsing multiple sclerosis (MS). Each drug has a different S1PR‐subtype selectivity. They target the G‐protein coupled S1P receptors and exert significant immunomodulatory effects, such as preventing the formation of new CNS lesions and the reactivation of pre ...
Faizan Shahzad +8 more
wiley +1 more source
The development of the mammalian jugular lymphsac, of the tributary primitive ulnar lymphatic and of the thoracic ducts from the view point of recent investigations of vertebrate lymphatic ontogeny, together with a consideration of the genetic relations of lymphatic and haemal vascular channels in the embryos of amniotes [PDF]
, 1914 Geo. S. Huntington
openalex +1 more source