Results 81 to 90 of about 66,627 (292)

Highly Active Cu14 Cluster Precisely Activates Autophagy Inhibitor to Amplify Cuproptosis Immunotherapy

Advanced Science, EarlyView.
An atomically precise Cu14 cluster‐mediated bond scission reaction pioneers the amplification of the antitumor immune response via synergetic cuproptosis‐associated immunogenic cell death induction and in situ autophagy blockade. ABSTRACT Transition metal‐mediated cleavage mechanisms have emerged as an effective means to mitigate the off‐target ...
Qiu‐Xu Zang, Wei‐Tong Chen, Yu‐Ying Shen, Zhao‐Yang Wang, Kai Li, Xueli Zhao, Yanjuan Sang, Xiaoyuan Chen, Shuang‐Quan Zang   +8 more
wiley   +1 more source

Lymphatic plastic bronchitis: a study based on CT and MR lymphangiography

BMC Medical Imaging
Objectives To investigate the diagnostic value of CT lymphangiography (CTL) and non-contrast MR lymphangiography (MRL) in lymphatic plastic bronchitis. Materials and methods The clinical and imaging data of 31 patients with lymphatic plastic bronchitis ...
Qi Hao, Yan Zhang, Xingpeng Li, Xiaoli Sun, Nan Hong, Rengui Wang   +5 more
doaj   +1 more source

Chromosomal abnormalities associated with fetal pleural effusion (II): Specific and non-specific chromosome aberrations

Taiwanese Journal of Obstetrics & Gynecology
Fetal pleural effusion has been reported to be associated with chromosomal abnormalities, genetic syndromes, obstructive uropathy, lymphatic vessel abnormalities such as Noonan syndrome, RASopathy and congenital lymphatic anomalies, thoracic cavity ...
Chih-Ping Chen
doaj   +1 more source

Physical therapies for reducing and controlling lymphoedema of the limbs. [PDF]

, 2008
Background Lymphoedema is the accumulation of excess fluid in the body caused by obstruction of the lymphatic drainage mechanisms. Management involves decongesting the reduced lymphatic pathways in order to reduce the size of the limb.
Ahmed, Andersen, Badger, Badger, Bergan, Bertelli, Carroll, Didem, Dini, Erickson, Foldi, Harris, Hornsby, Irdesel, Johansson, Johansson, Kligman, Levick, McKenzie, McNeely, Moffatt, Mortimer, Moseley, Petrek, Sitzia, Sitzia, Szuba, Szuba, Tobin, Wilburn, Williams   +30 more
core   +1 more source

GPCRs in CAR‐T Cell Immunotherapy: Expanding the Target Landscape and Enhancing Therapeutic Efficacy

Advanced Science, EarlyView.
Chimeric antigen receptor T cell therapy faces dual challenges of target scarcity and an immunosuppressive microenvironment in solid tumors. This review highlights how G protein‐coupled receptors can serve as both novel targets to expand the therapeutic scope and functional modules to enhance CAR‐T cell efficacy.
Zhuoqun Liu, Yuchen Xiao, Yamin Zhao, Lihe Dai, David J.H. Shih, Shikang Liang, Honglei Tian, Liu Liu, Feng Tian, Bing Liu, Lei Chang, Chao Zhang   +11 more
wiley   +1 more source

Syndromic and single gene disorders associated with fetal pleural effusion (I): Noonan syndrome, RASopathy and congenital lymphatic anomalies

Taiwanese Journal of Obstetrics & Gynecology
Fetal pleural effusion has been reported to be associated with chromosomal abnormalities, genetic syndromes, obstructive uropathy, lymphatic vessel abnormalities such as Noonan syndrome, RASopathy and congenital lymphatic anomalies, thoracic cavity ...
Chih-Ping Chen
doaj   +1 more source

HIF-1α promotes cellular growth in lymphatic endothelial cells exposed to chronically elevated pulmonary lymph flow

Scientific Reports, 2021
Normal growth and development of lymphatic structures depends on mechanical forces created by accumulating interstitial fluid. However, prolonged exposure to pathologic mechanical stimuli generated by chronically elevated lymph flow results in lymphatic ...
Jason T. Boehme, Catherine J. Morris, Samuel R. Chiacchia, Wenhui Gong, Katherine Y. Wu, Rebecca J. Kameny, Gary W. Raff, Jeffrey R. Fineman, Emin Maltepe, Sanjeev A. Datar   +9 more
doaj   +1 more source

Consumed by Abdominal Distention

Arthritis Care &Research, EarlyView.
Abimbola Fadairo‐Azinge, James Grenert, Brian Haas, Mary Margaretten   +3 more
wiley   +1 more source

Combination Immunotherapy as a Promising Strategy to Overcome Immunotherapy Resistance: From Emergence to Next‐Generation Approaches

Advanced Science, EarlyView.
This review examines emerging combination immunotherapy strategies tailored to distinct tumor microenvironments and highlights next‐generation biomarkers that guide response prediction and treatment personalization. It integrates lessons from unsuccessful trials, addresses toxicity challenges, and outlines approaches for early biomarker discovery and ...
Asmita Pandey, Sudhir Kumar Rai, Li Ma, Lauren Higa, Vedbar Khadka, Hua Yang, Youping Deng   +6 more
wiley   +1 more source

IL-2 Therapy Diminishes Renal Inflammation and the Activity of Kidney-Infiltrating CD4+ T Cells in Murine Lupus Nephritis [PDF]

, 2019
An acquired deficiency of interleukin-2 (IL-2) and related disturbances in regulatory T cell (Treg) homeostasis play an important role in the pathogenesis of systemic lupus erythematosus (SLE).
Burmester, Gerd-Rüdiger, Enghard, Philipp, Humrich, Jens, Kloke, Lutz, Kühl, Anja, Riemekasten, Gabriela, Rose, Angelika, von Spee-Mayer, Caroline, Wu, Kaiyin   +8 more
core   +2 more sources