Results 201 to 210 of about 105,489 (333)

Kaposi's sarcoma-associated herpesvirus infection of blood endothelial cells induces lymphatic differentiation

, 2004
Patrick A. Carroll, Elizabeth Brazeau, Michael Lagunoff   +2 more
openalex   +1 more source

Optimized Monothiol Thioredoxin Derivative (ORP100S) Protects In Vitro and In Vivo from Radiation and Chemotoxicity Without Promoting Tumor Proliferation

Advanced Science, EarlyView.
Native thioredoxin‐1 (TRX) stimulates proliferation and rescues stem cells and cancer cells from multiple stressors by suppressing p53 and inhibiting ferroptosis via GPX4/SLC7A11 upregulation mediated by enhanced KLF4 expression and p53 promoter binding.
Jian Wu, Xiaobei Wang, Parker Mathews, Shaima Jabbar, Min Zhang, Haim Moskowitz, Wei Duan, David P. Nichols, George William Schaaf, John D. Olson, Andrew N. Macintyre, J. Daniel Bourland, Ivan Spasojevic, Jen‐Tsan Ashley Chi, Joel Ross, Nelson Chao, J. Mark Cline, Peter B. Heifetz, Yubin Kang   +18 more
wiley   +1 more source

Lessons of Vascular Specialization From Secondary Lymphoid Organ Lymphatic Endothelial Cells. [PDF]

Circ Res, 2023
Arroz-Madeira S, Bekkhus T, Ulvmar MH, Petrova TV.   +3 more
europepmc   +1 more source

Lymphatic Endothelial Cells Adapt Their Barrier Function in Response to Changes in Shear Stress [PDF]

, 2009
Jerome W. Breslin, Kristine M Kurtz
openalex   +1 more source

Unveiling Macrophage Content as a Predictive Biomarker for Intraoperative ICG Imaging Efficacy in Lung Cancer

Advanced Science, EarlyView.
Indocyanine Green (ICG)‐guided lung cancer surgery efficacy varies significantly among patients. This study identifies tumor macrophage content as a predictive biomarker. Macrophages are primary ICG reservoirs, storing seven‐fold more ICG than cancer cells.
Yue Yan, Jiahui Mi, Yun Li, Guanchao Jiang, Yimeng Zhang, Yanguo Liu, Hui Zhao, Jianfeng Li, Xing Yang, Jun Wang, Fan Yang, Kezhong Chen, Yiguang Wang, Jian Zhou   +13 more
wiley   +1 more source

CD47 Activation by Thrombospondin-1 in Lymphatic Endothelial Cells Suppresses Lymphangiogenesis and Promotes Atherosclerosis. [PDF]

Arterioscler Thromb Vasc Biol, 2023
Singla B, Aithbathula RV, Pervaiz N, Kathuria I, Swanson M, Ekuban FA, Ahn W, Park F, Gyamfi M, Cherian-Shaw M, Singh UP, Kumar S.   +11 more
europepmc   +1 more source

EGFR: New Insights on Its Activation and Mutation in Tumor and Tumor Immunotherapy

Advanced Science, EarlyView.
This review provides new perspectives on EGFR's activation, mutations, and their impact on tumor immunotherapy. It summarizes how EGFR is activated and the current EGFR targeting strategy, evaluates their clinical outcomes in combination with immunotherapy, highlighting differential responses in tumors with EGFR wild‐type and different mutants.
Yuanzhuo Gu, Hongchao He, Shilei Qiao, Yifan Shao, Lurong Wang, Zhengkui Zhang, Long Zhang, Fangfang Zhou   +7 more
wiley   +1 more source

Macrophages define dermal lymphatic vessel calibre during development by regulating lymphatic endothelial cell proliferation [PDF]

, 2010
Emma Gordon, Sujata Rao, Jeffrey W. Pollard, Stephen L. Nutt, Richard A. Lang, Natasha L. Harvey   +5 more
openalex   +1 more source

Tendinopathy: The Interplay between Mechanical Stress, Inflammation, and Vascularity

Advanced Science, EarlyView.
This review explores the complex and self‐reinforcing cycle of mechanical stress, inflammation, and altered vascularity in tendinopathy—a common, painful tendon disorder. It integrates current findings on cellular, molecular, and biomechanical mechanisms, highlighting how mechanical overload, inflammatory signals, and abnormal blood vessel behavior ...
Renate Gehwolf, Herbert Tempfer, Nevra Pelin Cesur, Andrea Wagner, Andreas Traweger, Christine Lehner   +5 more
wiley   +1 more source

Saturated fatty acids induce lipotoxicity in lymphatic endothelial cells contributing to secondary lymphedema development. [PDF]

EMBO Mol Med
Gomes KP, Korodimas J, Liu E, Patel N, Yang X, Goruk S, Munhoz J, Field CJ, Gibson SB.   +8 more
europepmc   +1 more source