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The Lymphatics: On the Route to Cancer Metastasis
2011The blood vascular and lymphatic systems are necessary for the flux of gases, liquids, nutrients, signaling molecules, and cells among tissues and organs. These two highly branched, treelike networks are interconnected through the largest lymphatic vessel, the thoracic duct, which drains lymph, the protein-rich interstitial fluid, into the blood ...
Steven Stacker +3 more
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The Pathobiology of Metastasis Within the Lymphatic System
Surgical Oncology Clinics of North America, 1996This article focuses on the pathobiology of lymphatic metastases. The dynamics of metastasis within the lymphatic system are reviewed. Topics discussed include lymphatic channels, lymphati-covenous communication, metastatic inefficiency (which is a driving force in many aspects of the pathobiology of metastasis), and lymphogenous and hematogenous ...
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Historical Data on the Dynamics of Lymphatic Metastasis
Oncology, 1972A systematic survey of pre-20th century literature on metastasis to lymphatic tissues is presented under the five dynamic phases of liberation, transportation, deposition, establishment and growth ...
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The Lymphatic System in Breast Cancer Metastasis
2021The leading cause of breast cancer-associated death is metastasis. During metastasis, tumor cells metastasize from primary tumors to distant organs via the circulatory and lymphatic systems. However, in 80% of solid tumors, metastasis via the lymphatic system precedes metastasis via the vascular system.
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An experimental model for lymphatic metastasis in rats.
Gan, 1976An experimental model was described for inducing spontaneous lymph node metastasis, in which tumor cells of the rat ascites hepatoma AH-109A were transplanted into the subcutaneous tissue of the penis, which is rich of lymph plexus. Growth of tumor at the site of transplantation was measured serially and metastasis was recognized by palpation in the ...
Shizuko Shimizu, Hiroshi Takazawa
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Advanced Functional Materials, 2019
Lymphatic metastasis of tumor is one of leading causes of cancer‐related death, and diagnosing lymphatic metastasis is of significance in terms of optimal disease management and possible better outcomes for patients.
Yinglong Wu +4 more
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Lymphatic metastasis of tumor is one of leading causes of cancer‐related death, and diagnosing lymphatic metastasis is of significance in terms of optimal disease management and possible better outcomes for patients.
Yinglong Wu +4 more
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Role of the lymphatics in cancer metastasis and chemotherapy applications
Advanced Drug Delivery Reviews, 2011The lymphatic system was first described centuries ago. The recent discovery of various molecular markers has allowed for more in-depth research of the lymphatic system and its role in health and disease. The lymphatic system has recently been elucidated as playing an active role in cancer metastasis.
Jennifer D. McAllaster, Mark S. Cohen
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Lymphatic metastasis in apparently early carcinoma of the ovary
Gynecologic Oncology, 1981Direct extension of ovarian carcinoma to contiguous structures and intraabdominal involvement via dissemination of exfoliated tumor cells is well recognized. The importance of metastatic spread via abdominal and pelvic lymphatics, especially in the absence of other forms of spread, is less well described.
Robert F. Karnei +9 more
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[Recent advances on lymphangiogenesis and lymphatic metastasis].
Zhonghua bing li xue za zhi = Chinese journal of pathology, 2007在肿瘤转移机制的研究中,有关淋巴管生成与肿瘤转移关系的研究近年来已逐渐成为热点,肿瘤淋巴系统作为肿瘤尤其是实体瘤转移的重要通道的研究意义也不断被认识.临床病理学研究显示实体瘤播散的最早途径是经淋巴道的区域性淋巴结播散[1],但目前对此转移途径的相关研究仍处于比较基础的阶段,不像对肿瘤血管系统的研究那样广泛和深入.现就肿瘤淋巴管生成与淋巴道转移的研究现状作一简要综述。
Li Fu, Fang Fang Liu, Rong Gang Lang
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