Off‐The‐Shelf Multivalent Nanoconjugate Cancer Vaccine Rescues Host Immune Response against Melanoma
A star‐shaped cross‐linked polyglutamate (StCl) nanocarrier delivers melanoma‐associated peptide antigens via redox‐responsive linkers, inducing lymph node‐targeted antigen presentation. The nanoconjugate activates dendritic cells, promotes effector T‐cell responses, and enables tumor regression even in humanized patient‐derived preclinical models ...
Liane IF Moura+19 more
wiley +1 more source
Unraveling the lymphatic system in the spinal cord meninges: a critical element in protecting the central nervous system. [PDF]
Gonuguntla S, Herz J.
europepmc +1 more source
Lymphatic filariasis in Ghana: entomological investigation of transmission dynamics and intensity in communities served by irrigation systems in the Upper East Region of Ghana [PDF]
Maxwell A. Appawu+3 more
openalex +1 more source
3D Printed Magnetic Origami Scaffolds for Guided Tissue Assembly
3D‐printed magnetic origami scaffolds enhance 3D coculture by directing cell proliferation pre‐folding, restricting expansion for controlled growth within the channel, and spatially and temporally promoting 3D multicellular dissemination post‐folding.
Brandon Daul+6 more
wiley +1 more source
The lymphatic system: a therapeutic target for central nervous system disorders. [PDF]
Xu JQ+6 more
europepmc +1 more source
The rediscovery of the lymphatic system: old and new insights into the development and biological function of the lymphatic vasculature [PDF]
Guillermo Oliver, Michael Detmar
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This work presents an injectable polymer‐nanoparticle hydrogel depot platform for delivering multivalent influenza vaccines which induces stronger and more durable immune responses. The technology provides broader protection, including against heterologous and potential pandemic strains (H5N1, H7N9, H9N2), and enhances the effectiveness of commercial ...
Olivia M. Saouaf+7 more
wiley +1 more source
Nanotechnologies for Physiology-Informed Drug Delivery to the Lymphatic System. [PDF]
Maisel K+3 more
europepmc +1 more source