Results 191 to 200 of about 830,619 (333)
Current topics of physiology and pharmacology in the lymphatic system [PDF]
Toshio Ohhashi+3 more
openalex +1 more source
Targeting KMT5C Suppresses Lung Cancer Progression and Enhances the Efficacy of Immunotherapy
This study reveals that KMT5C activates DNA damage repair to inhibit STING‐IRF3 pathway, downstream type I IFN signaling and CCL5 secretion, leading to the downregulation of CD8+ T cell infiltration and function in NSCLC, ultimately facilitating tumor progression.
Yunfeng Yuan+11 more
wiley +1 more source
Lymphatic system regulation of anti-cancer immunity and metastasis. [PDF]
Lei PJ+4 more
europepmc +1 more source
Cracking the intestinal lymphatic system window utilizing oral delivery vehicles for precise therapy. [PDF]
Miao YB+6 more
europepmc +1 more source
An embedded bioprinting enabled‐arrayed patient‐derived organoids (Eba‐PDO) platform that replicates intrinsic and extrinsic tumor characteristics is introduced. Eba‐PDOs more accurately mimic tissue than standard PDOs (Std‐PDOs) due to maturation in the tumor microenvironment.
Jonghyeuk Han+15 more
wiley +1 more source
Fluid dynamics and leukocyte transit in the lymphatic system. [PDF]
Li H+4 more
europepmc +1 more source
The lymphatic system and COVID-19 vaccines. [PDF]
Miyasaka M.
europepmc +1 more source
RNF112, an E3 ubiquitin ligase, is markedly reduced in bladder cancer (BLCA). It curbs BLCA cell proliferation, migration, and lipid production primarily by enhancing ubiquitin‐dependent degradation of c‐Myc. This degradation inhibits c‐Myc's role in upregulating ACLY, a crucial enzyme for lipid synthesis, highlighting RNF112's potential as a ...
Kangping Xiong+13 more
wiley +1 more source