Results 191 to 200 of about 830,619 (333)

Current topics of physiology and pharmacology in the lymphatic system [PDF]

open access: green, 2004
Toshio Ohhashi   +3 more
openalex   +1 more source

Targeting KMT5C Suppresses Lung Cancer Progression and Enhances the Efficacy of Immunotherapy

open access: yesAdvanced Science, EarlyView.
This study reveals that KMT5C activates DNA damage repair to inhibit STING‐IRF3 pathway, downstream type I IFN signaling and CCL5 secretion, leading to the downregulation of CD8+ T cell infiltration and function in NSCLC, ultimately facilitating tumor progression.
Yunfeng Yuan   +11 more
wiley   +1 more source

Lymphatic system regulation of anti-cancer immunity and metastasis. [PDF]

open access: yesFront Immunol
Lei PJ   +4 more
europepmc   +1 more source

Cracking the intestinal lymphatic system window utilizing oral delivery vehicles for precise therapy. [PDF]

open access: yesJ Nanobiotechnology, 2023
Miao YB   +6 more
europepmc   +1 more source

Bioprinted Patient‐Derived Organoid Arrays Capture Intrinsic and Extrinsic Tumor Features for Advanced Personalized Medicine

open access: yesAdvanced Science, EarlyView.
An embedded bioprinting enabled‐arrayed patient‐derived organoids (Eba‐PDO) platform that replicates intrinsic and extrinsic tumor characteristics is introduced. Eba‐PDOs more accurately mimic tissue than standard PDOs (Std‐PDOs) due to maturation in the tumor microenvironment.
Jonghyeuk Han   +15 more
wiley   +1 more source

Fluid dynamics and leukocyte transit in the lymphatic system. [PDF]

open access: yesPNAS Nexus
Li H   +4 more
europepmc   +1 more source

RNF112 Facilitates Ubiquitin‐Mediated Degradation of c‐Myc, Suppressing Proliferation, Migration and Lipid Synthesis in Bladder Cancer

open access: yesAdvanced Science, EarlyView.
RNF112, an E3 ubiquitin ligase, is markedly reduced in bladder cancer (BLCA). It curbs BLCA cell proliferation, migration, and lipid production primarily by enhancing ubiquitin‐dependent degradation of c‐Myc. This degradation inhibits c‐Myc's role in upregulating ACLY, a crucial enzyme for lipid synthesis, highlighting RNF112's potential as a ...
Kangping Xiong   +13 more
wiley   +1 more source

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