Results 201 to 210 of about 22,262,144 (390)

Lymphoid and CXCR4 Cell Targeted Lipid Nanoparticles Facilitate HIV‐1 Proviral DNA Excision

open access: yesAdvanced Healthcare Materials, EarlyView.
Advancements in ART improve HIV‐1 patient outcomes but are unable to eliminate latent viral DNA. To address this, CXCR4‐targeted lipid nanoparticles (T‐LNPs) for delivering CRISPR‐Cas9 to excise HIV‐1 DNA in infected cells are developed. These T‐LNPs achieve ≈60% HIV‐1 DNA excision efficacy in blood and splenic tissue, demonstrating promise for ...
Sudipta Panja   +6 more
wiley   +1 more source

Influence of substancies of biological nature in minute doses on tissue lymphatic drainage

open access: yesRUDN Journal of Ecology and Life Safety, 2011
Cleanliness per cellular spaces is provided with a condition tissue lymphatic drainage. Infringements tissue lymphatic drainage make key links pathogenesis diseases of a various etiology and define of their current and an outcompete.
E V Artamonova
doaj  

Immunosuppressive Formulations for Immunological Defense against Traumatic Brain Injury

open access: yesAdvanced Healthcare Materials, EarlyView.
A novel subcutaneous formulation combining alpha‐ketoglutarate, glycolysis inhibitor PFK15, and a myelin peptide reduces inflammation in a mouse TBI model. This formulation promotes regulatory immune cells, enhances autophagy, and improves motor function, suggesting its potential as a prophylactic immunosuppressive therapy to mitigate TBI‐induced ...
Kelly Lintecum   +28 more
wiley   +1 more source

A soft, bioinspired artificial lymphatic system for interactive ascites transfer. [PDF]

open access: yesBioeng Transl Med, 2023
Wang P   +7 more
europepmc   +1 more source

Imiquimod‐Loaded Phospholipid‐Free Small Unilamellar Vesicles Activate the Tumor Immune Microenvironment to Treat Liver Cancer and Liver Metastases

open access: yesAdvanced Healthcare Materials, EarlyView.
Imiquimod‐loaded nanoparticles (PFSUV‐IMQ) are found to decrease liver metastasis and liver tumor burden when administered intravenously. Flow cytometry, RNA‐seq and various experiments show that the anti‐tumor response is immune‐mediated by activating dendritic cells resulting in increased CD8 T cell infiltration and activity.
Vanessa Chan   +13 more
wiley   +1 more source

Robotic-assisted Lymphovenous Anastomosis of the Central Lymphatic System. [PDF]

open access: yesPlast Reconstr Surg Glob Open
Grünherz L   +10 more
europepmc   +2 more sources

Microanatomical organization of hepatic venous lymphatic system in humans. [PDF]

open access: yesPLoS One, 2023
Umemura K   +11 more
europepmc   +1 more source

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