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Radiotherapy induces tumor cells to release microparticles (RT‐MPs) into the circulation. The mitochondrial DNA carried by these RT‐MPs activates the STING/NLRP3/GSDMD axis in splenic neutrophils, triggering IL‐1β secretion. This, in turn, enhances dendritic cell function and facilitates the formation of cytotoxic T lymphocytes, thereby promoting ...
Yan Hu +18 more
wiley +1 more source
GlycoChat Uncovers Glycan–Lectin Circuits in the Tumor Microenvironment of Pancreatic Cancer
Aberrant glycosylation drives cancer progression, yet its role in the tumor microenvironment remains unclear. We developed GlycoChat to map glycan–lectin circuits at single‐cell resolution. We discovered that cancer cells induce immunosuppressive macrophage differentiation and impair phagocytosis through interactions with CLEC10A and SIGLEC3 ...
Dinh Xuan Tuan Anh +8 more
wiley +1 more source
Editorial for the Special Issue "Vasorum Lymphaticorum: From the Discovery of the Lymphatic System to the New Perspectives in Microsurgical Reconstruction and Patient Rehabilitation". [PDF]
Bolletta A, Losco L, Cigna E.
europepmc +1 more source
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Nursing Standard, 2012
This article, which forms part of the life sciences series, examines the lymphatic system, focusing on the anatomy and physiology of lymphatic vessels, lymph nodes and lymph fluid. The flow of lymph through the body is described and the regulatory mechanisms involved are identified and discussed.
Ella, McLafferty +2 more
openaire +3 more sources
This article, which forms part of the life sciences series, examines the lymphatic system, focusing on the anatomy and physiology of lymphatic vessels, lymph nodes and lymph fluid. The flow of lymph through the body is described and the regulatory mechanisms involved are identified and discussed.
Ella, McLafferty +2 more
openaire +3 more sources
Annual Review of Physiology, 1952
The literature dealt with in this paper is by no means all-inclusive for the period since 1949. Only those articles dealing directly with lymphatic vessels or lymph nodes are reviewed. No attempt has been made to catalogue all references to lymph nodes mentioned in clinical literature. That some sub.
openaire +2 more sources
The literature dealt with in this paper is by no means all-inclusive for the period since 1949. Only those articles dealing directly with lymphatic vessels or lymph nodes are reviewed. No attempt has been made to catalogue all references to lymph nodes mentioned in clinical literature. That some sub.
openaire +2 more sources
2005
Abstract The lymphatic system plays a fundamental part in regulating the physiologic environment by returning protein, cells, mac- romolecules, and fluid to the bloodstream, as well as by removing metabolic byproducts, dying or mutant cells, microbes, and inorganic matter. It also acts as a conduit for trafficking immune cell populations.
openaire +1 more source
Abstract The lymphatic system plays a fundamental part in regulating the physiologic environment by returning protein, cells, mac- romolecules, and fluid to the bloodstream, as well as by removing metabolic byproducts, dying or mutant cells, microbes, and inorganic matter. It also acts as a conduit for trafficking immune cell populations.
openaire +1 more source

