Results 51 to 60 of about 830,619 (333)

FUNCTIONAL AND ANATOMICAL FEATURES OF THE LYMPHOVENOUS JUNCTION

open access: yesПаёми Сино, 2022
The article presents a general description of the lymphatic system and detailed characteristics of the structure of the terminal thoracic duct (TD) and lymphovenous junction (LVJ): their clinical and anatomical features, the role of LVJ in regulating ...
SH.KH. GANTSEV   +5 more
doaj   +1 more source

Development and Clinical Validation of the LymphMonitor Technology to Quantitatively Assess Lymphatic Function

open access: yesDiagnostics, 2021
Current diagnostic methods for evaluating the functionality of the lymphatic vascular system usually do not provide quantitative data and suffer from many limitations including high costs, complexity, and the need to perform them in hospital settings. In
Anna Polomska   +6 more
doaj   +1 more source

Imaging technology of the lymphatic system

open access: yesAdvanced Drug Delivery Reviews, 2021
ISSN:0169 ...
Polomska, Anna K., Proulx, Steven T.
openaire   +4 more sources

FoxO1 signaling in B cell malignancies and its therapeutic targeting

open access: yesFEBS Letters, EarlyView.
FoxO1 has context‐specific tumor suppressor or oncogenic character in myeloid and B cell malignancies. This includes tumor‐promoting properties such as stemness maintenance and DNA damage tolerance in acute leukemias, or regulation of cell proliferation and survival, or migration in mature B cell malignancies.
Krystof Hlavac   +3 more
wiley   +1 more source

Engineering the Lymphatic System [PDF]

open access: yesCardiovascular Engineering and Technology, 2011
The recent advances in our understanding of lymphatic physiology and the role of the lymphatics in actively regulating fluid balance, lipid transport, and immune cell trafficking has been furthered in part through innovations in imaging, tissue engineering, quantitative biology, biomechanics, and computational modeling.
Matthew E. Nipper, J. Brandon Dixon
openaire   +3 more sources

The immunological interface: dendritic cells as key regulators in metabolic dysfunction‐associated steatotic liver disease

open access: yesFEBS Letters, EarlyView.
Metabolic dysfunction‐associated steatotic liver disease (MASLD) affects nearly one‐third of the global population and poses a significant risk of progression to cirrhosis or liver cancer. Here, we discuss the roles of hepatic dendritic cell subtypes in MASLD, highlighting their distinct contributions to disease initiation and progression, and their ...
Camilla Klaimi   +3 more
wiley   +1 more source

Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia

open access: yesFEBS Letters, EarlyView.
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley   +1 more source

Pump efficacy in a fluid-structure interaction model of a chain of contracting lymphangions [PDF]

open access: yesarXiv, 2020
The transport of lymph through the lymphatic vasculature is the mechanism for returning excess interstitial fluid to the circulatory system, and it is essential for fluid homeostasis. Collecting lymphatic vessels comprise a significant portion of the lymphatic vasculature and are divided by valves into contractile segments known as lymphangions ...
arxiv  

Is There a Cerebral Lymphatic System? [PDF]

open access: yesStroke, 2013
The brain is unique among virtually all somatic organs in its lack of a conventional lymphatic vasculature.1–3 In the periphery, the lymphatic circulation facilitates the clearance of extracellular proteins and excess fluid from the interstitium, a role critical to tissue homeostasis and function.4,5 Yet within the brain, despite its complex ...
Jeffrey J, Iliff, Maiken, Nedergaard
openaire   +3 more sources

The cytoskeletal control of B cell receptor and integrin signaling in normal B cells and chronic lymphocytic leukemia

open access: yesFEBS Letters, EarlyView.
In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley   +1 more source

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