Hallmarks of Neuroblastoma—Pathophysiology, Diagnosis, and Therapeutic Interventions
ABSTRACT Neuroblastoma, the most common extracranial solid tumor in childhood, continues to challenge clinicians and researchers because of its heterogeneous nature and complex pathophysiology. Recent breakthroughs in molecular profiling revealed intricate genetic alterations driving tumor progression, necessitating an updated perspective on the ...
Abhimanyu Thakur, Anne Dijkstra
wiley +1 more source
Loss of ERG function causes lymphatic vessel malformations and primary lymphoedema
Pirri D+36 more
europepmc +1 more source
Lymphatic vessel transit seeds cytotoxic resident memory T cells in skin draining lymph nodes. [PDF]
Heim TA+6 more
europepmc +1 more source
ABSTRACT Solitary fibrous tumors (SFTs) are rare neoplasms characterized by spindle neoplastic cell proliferation within collagenous stroma and prominent dilated vasculature. They present a wide histopathological spectrum, ranging from hypocellular lesions with a rich collagenous stroma to hypercellular lesions with scant stroma.
Hiroyuki Okanishi+10 more
wiley +1 more source
Expert Perspective: Hematologic Malignancies and Vasculitis
Arthritis &Rheumatology, EarlyView.
Michelle L. Robinette, Hetty E. Carraway
wiley +1 more source
Redefining the Skin Barrier: A Microbiome‐Integrated Multilayered Defense Model
ABSTRACT The skin constitutes a dynamic interface orchestrating a sophisticated multilayered defense system comprising physical, chemical, immune, and microbial barriers. This review synthesizes current understanding of the structural and functional integration of these barriers, emphasizing their synergistic interactions in maintaining cutaneous ...
Jingjing Xia+4 more
wiley +1 more source
Increased Microvascular Filtration and Vascular Endothelial Growth Factor-D associated with Changed Lymphatic Vessel Morphology in Breast Cancer Treated Patients. [PDF]
Johannessen AL+5 more
europepmc +1 more source
A 2D axisymmetric computational model for the study of mass transport into lymphatic capillaries and pre-collector vessels [PDF]
Adeli Koudehi, Ghazal+4 more
core
Dynamics of primary cilia in endothelial and mesenchymal cells throughout mouse lung development
Abstract Cilia are specialized structures found on a variety of mammalian cells, with variable roles in the transduction of mechanical and biological signals (by primary cilia, PC), as well as in the generation of fluid flow (by motile cilia). Their critical role in the establishment of a left–right axis in early development is well described, as well ...
Stephen Spurgin+8 more
wiley +1 more source
FOXC1 and FOXC2 Ablation Causes Abnormal Valvular Endothelial Cell Junctions and Lymphatic Vessel Formation in Myxomatous Mitral Valve Degeneration. [PDF]
Tan C+6 more
europepmc +1 more source