Results 71 to 80 of about 1,011,532 (393)

An Evolutionarily Conserved Role for Polydom/Svep1 During Lymphatic Vessel Formation

Circulation Research, 2017
Rationale: Lymphatic vessel formation and function constitutes a physiologically and pathophysiologically important process, but its genetic control is not well understood.
Terhi Karpanen, Y. Padberg, S. A. van de Pavert, Cathrin Dierkes, Nanami Morooka, J. Peterson-Maduro, Glenn van de Hoek, Max Adrian, N. Mochizuki, K. Sekiguchi, F. Kiefer, Dörte Schulte, S. Schulte-Merker   +12 more
semanticscholar   +1 more source

Understanding and measuring mechanical signals in the tumor stroma

FEBS Open Bio, EarlyView.
This review discusses cancer‐associated fibroblast subtypes and their functions, particularly in relation to extracellular matrix production, as well as the development of 3D models to study tumor stroma mechanics in vitro. Several quantitative techniques to measure tissue mechanical properties are also described, to emphasize the diagnostic and ...
Fàtima de la Jara Ortiz, Chiara Cimmino, Maurizio Ventre, Alessandra Cambi   +3 more
wiley   +1 more source

Lymphatic Mapping for LVA with Noncontrast Lymphatic Ultrasound: How We Do It

Plastic and Reconstructive Surgery, Global Open
Summary:. Recently, lymphatic ultrasonography has received increasing attention. Although there are several reports on contrast-enhanced lymphatic ultrasound as a preoperative examination for lymphaticovenous anastomosis (LVA), we have been reporting the
Hisako Hara, MD, PhD, Michiru Ichinose, RN, Fumika Shimomura, RN, Mari Kawahara, MD, Makoto Mihara, MD   +4 more
doaj   +1 more source

Bioengineering facets of the tumor microenvironment in 3D tumor models: insights into cellular, biophysical and biochemical interactions

FEBS Open Bio, EarlyView.
The tumor microenvironment is a dynamic, multifaceted complex system of interdependent cellular, biochemical, and biophysical components. Three‐dimensional in vitro models of the tumor microenvironment enable a better understanding of these interactions and their impact on cancer progression and therapeutic resistance.
Salma T. Rafik, Deniz Bakkalci, Alexander J. MacRobert, Umber Cheema   +3 more
wiley   +1 more source

Visualization of Endothelial Actin Cytoskeleton in the Mouse Retina [PDF]

, 2012
Angiogenesis requires coordinated changes in cell shape of endothelial cells (ECs), orchestrated by the actin cytoskeleton. The mechanisms that regulate this rearrangement in vivo are poorly understood - largely because of the difficulty to visualize ...
Alessia Fraccaroli, Attila Aszodi, Claudio A Franco, Eloi Montanez, Emanuel Rognoni, Filipa Neto, Holger Gerhardt, Holger Gerhardt, Markus Rehberg, Roland Wedlich-Söldner, Ulrich Pohl   +10 more
core   +5 more sources

Current trends in single‐cell RNA sequencing applications in diabetes mellitus

FEBS Open Bio, EarlyView.
Single‐cell RNA sequencing is a powerful approach to decipher the cellular and molecular landscape at a single‐cell resolution. The rapid development of this technology has led to a wide range of applications, including the detection of cellular and molecular mechanisms and the identification and introduction of novel potential diagnostic and ...
Seyed Sajjad Zadian, Khodakaram Jahanbin, Shekoofeh Nikooei, Marzieh Rostaminejad, Arezoo Rahimi, Pedram Abdizadeh, Behnam Alipoor   +6 more
wiley   +1 more source

EphrinB2-EphB4 signalling provides Rho-mediated homeostatic control of lymphatic endothelial cell junction integrity

eLife, 2020
Endothelial integrity is vital for homeostasis and adjusted to tissue demands. Although fluid uptake by lymphatic capillaries is a critical attribute of the lymphatic vasculature, the barrier function of collecting lymphatic vessels is also important by ...
Maike Frye, Simon Stritt, Henrik Ortsäter, Magda Hernandez Vasquez, Mika Kaakinen, Andres Vicente, John Wiseman, Lauri Eklund, Jorge L Martínez-Torrecuadrada, Dietmar Vestweber, Taija Mäkinen   +10 more
doaj   +1 more source

Effects of ionizing radiation on normal and tumor-associated lymphatic vessels [PDF]

, 2007
Thesis (S.B.)--Massachusetts Institute of Technology, Dept. of Nuclear Science and Engineering, 2007."June 2007."Includes bibliographical references (p. 37-43).Lymphatic vessels play a crucial role in both the pathophysiology of tumors and in the spread ...
Lobo, Jennifer D
core  

Blood flow-induced Notch activation and endothelial migration enable vascular remodeling in zebrafish embryos. [PDF]

, 2018
Arteries and veins are formed independently by different types of endothelial cells (ECs). In vascular remodeling, arteries and veins become connected and some arteries become veins. It is unclear how ECs in transforming vessels change their type and how
Ablooglu, Ararat J, Groisman, Alex, Gutierrez, Edgar, Saikin, Semion K, Tkachenko, Eugene, Traver, David, Weijts, Bart   +6 more
core   +3 more sources

Understanding Mechanisms of Whole Brain and Regional Grey Matter Atrophy in Children With MOGAD

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To investigate the mechanisms driving whole brain and regional grey matter (GM) volume changes along with their clinical correlates in paediatric myelin oligodendrocyte glycoprotein antibody (MOG‐Ab)–associated disease (MOGAD). Methods One‐hundred‐nine paediatric MOGAD patients from two UK centres underwent MRI at attack nadir and ...
Ermelinda De Meo, Riccardo Nistri, Michael Eyre, Cheryl Hemingway, Ming Lim, Thomas Rossor, Asthik Biswas, Kshitij Mankad, Ata Siddiqui, Sniya Sudhakar, Declan Chard, Frederik Barkhof, Arman Eshaghi, Olga Ciccarelli, Yael Hacohen   +14 more
wiley   +1 more source