Results 11 to 20 of about 47,201 (286)
Current Concepts in the Management of Primary Lymphedema
Medicina, 2023 Primary lymphedema is a heterogeneous group of conditions encompassing all lymphatic anomalies that result in lymphatic swelling. Primary lymphedema can be difficult to diagnose, and diagnosis is often delayed. As opposed to secondary lymphedema, primary
Jenna-Lynn B. Senger +2 more
doaj +2 more sources
Scientific Reports, 2021 We examined cross-sectional associations between arm lymphedema symptoms and health-related quality of life (HRQoL) in the Health, Eating, Activity and Lifestyle (HEAL) Study.
Kayo Togawa +9 more
doaj +2 more sources
BMC Cancer, 2020 Background Little is known about the prevalence and incidence in low and middle-income countries (LMICs) of secondary lymphedema due to cancer. The purpose of the study is to estimate the prevalence and incidence in LMICs of secondary lymphedema related ...
Eric Torgbenu +4 more
doaj +2 more sources
Phlebology, 2022 Background Lymphedema imposes a significant economic and social burden in modern societies. Controversies about its risk factors, diagnosis, and treatment permeate the literature.
F. Lurie +12 more
semanticscholar +1 more source
TGF‐β1 mediates pathologic changes of secondary lymphedema by promoting fibrosis and inflammation
Clinical and Translational Medicine, 2022 Background Secondary lymphedema is a common complication of cancer treatment, and previous studies have shown that the expression of transforming growth factor‐beta 1 (TGF‐β1), a pro‐fibrotic and anti‐lymphangiogenic growth factor, is increased in this ...
J. Baik +12 more
semanticscholar +1 more source
The molecular genetics of RASopathies: An update on novel disease genes and new disorders
American Journal of Medical Genetics Part C: Seminars in Medical Genetics, Volume 190, Issue 4, Page 425-439, December 2022., 2022 Abstract Enhanced signaling through RAS and the mitogen‐associated protein kinase (MAPK) cascade underlies the RASopathies, a family of clinically related disorders affecting development and growth. In RASopathies, increased RAS‐MAPK signaling can result from the upregulated activity of various RAS GTPases, enhanced function of proteins positively ...
Marco Tartaglia +2 more
wiley +1 more source
Medicina, 2022 Lymphedema is a chronic disabling condition affecting a growing number of patients worldwide. Although lymphedema is not life-threatening, several reports underlined detrimental consequences in terms of distress, pain, functional impairment, and ...
A. de Sire +11 more
semanticscholar +1 more source
Clinical overview on RASopathies
American Journal of Medical Genetics Part C: Seminars in Medical Genetics, Volume 190, Issue 4, Page 414-424, December 2022., 2022 Abstract RASopathies comprise a group of clinically overlapping developmental disorders caused by genetic variations affecting components or modulators of the RAS‐MAPK signaling cascade, which lead to dysregulation of signal flow through this pathway.
Martin Zenker
wiley +1 more source
Current Mechanistic Understandings of Lymphedema and Lipedema: Tales of Fluid, Fat, and Fibrosis
International Journal of Molecular Sciences, 2022 Lymphedema and lipedema are complex diseases. While the external presentation of swollen legs in lower-extremity lymphedema and lipedema appear similar, current mechanistic understandings of these diseases indicate unique aspects of their underlying ...
Bailey H. Duhon +4 more
semanticscholar +1 more source
Cancers, 2022 Simple Summary Prostate cancer patients that receive treatment (surgery of radiation therapy) directed to the pelvic lymph nodes may suffer from secondary lymphedema in the lower limbs and/or the genital area.
A. Clinckaert +8 more
semanticscholar +1 more source