Results 51 to 60 of about 45,718 (214)

Yield of Whole Genome Sequencing for Pathogenic Single Nucleotide Variants in Congenital Heart Disease: A Systematic Review and Meta‐Analysis

Prenatal Diagnosis, EarlyView.
ABSTRACT Objective This systematic review and meta‐analysis aimed to assess the diagnostic yield of pathogenic or likely pathogenic (P/LP) single nucleotide variants (SNVs) using whole genome sequencing (WGS) in congenital heart disease (CHD). Methods A systematic search of three databases (2000–2024) was conducted, and two reviewers independently ...
Hiba J. Mustafa, Parisa Najjariasl, Faezeh Aghajani, Enaja V. Sambatur, Andrew Rodenbarger, Stephanie Guseh, Amy E. Roberts, Alireza A. Shamshirsaz   +7 more
wiley   +1 more source

Diagnostic Accuracy of Lymphoscintigraphy for Lymphedema and Analysis of False-Negative Tests

Plastic and Reconstructive Surgery, Global Open, 2017
Background:. Lymphedema is the chronic enlargement of tissue due to inadequate lymphatic function. Diagnosis is made by history and physical examination and confirmed with lymphoscintigraphy.
Aladdin H. Hassanein, MD, MMSc, Reid A. Maclellan, MD, MMSc, Frederick D. Grant, MD, Arin K. Greene, MD, MMSc   +3 more
doaj   +1 more source

Treatment with YIGSR peptide ameliorates mouse tail lymphedema by 67 kDa laminin receptor (67LR)-dependent cell-cell adhesion

Biochemistry and Biophysics Reports, 2023
Impaired microcirculation can cause lymphatic leakage which leads to a chronic swelling in the tissues of the body. However, no successful treatment gives any protection against lymphedema due to the lack of well-revealed pathophysiology of secondary ...
Y. Sakae, H. Takada, S. Ichinose, M. Nakajima, A. Sakai, R. Ogawa   +5 more
doaj   +1 more source

Cystoscopic ICG‐Guided Sentinel Lymph Node Dissection in Robotic Radical Prostatectomy: A Prospective Study

The Prostate, EarlyView.
ABSTRACT Background To evaluate the diagnostic accuracy, procedural feasibility, and clinical outcomes of a novel cystoscopic‐guided indocyanine green (ICG) injection technique followed by fluorescence‐guided sentinel lymph node dissection (SLND) during robotic‐assisted radical prostatectomy (RaRP), hereafter referred to as CysICG‐SLND.
Yi Hong Li, Yu Feng Chuang, Yen Chuan Ou, Yi Sheng Lin, Li Hua Huang, Wei Chun Weng, Chao Yu Hsu, Min Che Tung   +7 more
wiley   +1 more source

Elephantiasis nostras verrucosa: an atypical presentation following intrapelvic lymphoma [PDF]

, 2019
Elephantiasis nostras verrucosa is a progressively debilitating and disfiguring disease commonly presenting with verrucous, cobblestone-like papules, nodules, or plaques with nonpitting edema in the lower extremities.
Dahle, Sara E, Hadian, Yasmin, Isseroff, R Rivkah, Link, Daniel   +3 more
core  

Constitutional symptoms and response to Penicillin G in erysipelas and cellulitis – a monocentric, retrospective, explorative study

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary Background: Erysipelas, caused by streptococci, should be treated with penicillin, while uncomplicated cellulitis (phlegmon), often caused by Staphylococcus aureus, requires penicillinase‐resistant beta‐lactam antibiotics, which have a higher risk of adverse effects. Distinguishing between these infections is important.
Helena Schieffers, Cord Sunderkötter
wiley   +1 more source

Primary Lymphedema: Anatomically Isolated or a Pervasive Systemic Disorder?

Plastic and Reconstructive Surgery, Global Open
Background:. Primary lymphedema, a condition characterized by impaired lymphatic function, has long remained underexplored. Current diagnostic approaches rely on clinical history and genetic testing, yet the genetic underpinnings remain elusive in many ...
Wei F. Chen, MD, FACS, Christopher Jou, MD, Sonia K. Pandey, MD, Shih-Lun Lo, MD   +3 more
doaj   +1 more source

Complete lymph node dissection versus selective lymph node extirpation in melanoma patients with nodal macrometastasis and adjuvant systemic therapy

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary Background and Objectives Complete lymph node dissection (CLND) is the standard of care in patients with regional nodal melanoma macrometastasis. However, evidence on surgical procedures in the era of adjuvant systemic therapies is lacking. Patients and Methods This retrospective multi‐center study included stage IIIB–D melanoma patients with ...
Kristine E. Mayer, Jessica C. Hassel, Jannik Sambale, Michael Erdmann, Mihaela‐Anca Sindrilaru, Julia Oberschmied, Alexander Thiem, Dirk Tomsitz, Jana Knuever, Max Schlaak, Carola Berking, Christian Posch, Tilo Biedermann, Oana‐Diana Persa   +13 more
wiley   +1 more source

Evaluating the Quality of Life and Sleep Quality in Saudi Women with Breast Cancer-Related Lymphedema: A Cross-Sectional Correlational Study

Integrative Cancer Therapies, 2021
Background Among the different cancers found in women, breast cancer is the most common. Breast cancer-related lymphedema is a serious health complication affecting the quality of life and sleep quality. This study evaluates the quality of life and sleep
Nissren Tamam, K. S. Al-Mugren, H. I. Alrebdi, Abdelmoneim Sulieman, Walid Kamal Abdelbasset   +4 more
doaj   +1 more source

Behind the scenes: how the EMILIN/Multimerin family shapes the cancer landscape

The FEBS Journal, EarlyView.
The EMILIN/Multimerin family members regulate key hallmarks of cancer—including apoptosis, angiogenesis, metastasis, and tumor microenvironment remodeling. As indicated, their function in immune evasion, drug resistance, and metabolic reprogramming remains largely unexplored.
Evelina Poletto, Naike Casagrande, Emanuele Di Siena, Greta Carobolante, Lucrezia Camicia, Giorgia Schinello, Samanta Muzzin, Enrica Timis, Paola Spessotto, Maurizio Mongiat   +9 more
wiley   +1 more source