Results 121 to 130 of about 555,062 (342)

Childhood Acute Lymphoblastic Leukemia: Progress Through Collaboration.

Journal of Clinical Oncology, 2015
PURPOSE To review the impact of collaborative studies on advances in the biology and treatment of acute lymphoblastic leukemia (ALL) in children and adolescents.
C. Pui, Jun J. Yang, S. Hunger, R. Pieters, M. Schrappe, A. Biondi, A. Vora, A. Baruchel, L. Silverman, K. Schmiegelow, G. Escherich, K. Horibe, Y. Benoît, S. Izraeli, A. Yeoh, D. Liang, J. Downing, W. Evans, M. Relling, C. Mullighan   +19 more
semanticscholar   +1 more source

Genetic Basis of Acute Lymphoblastic Leukemia.

Journal of Clinical Oncology, 2017
Acute lymphoblastic leukemia (ALL) is the most common childhood cancer, and despite cure rates exceeding 90% in children, it remains an important cause of morbidity and mortality in children and adults.
I. Iacobucci, C. Mullighan
semanticscholar   +1 more source

Mechanisms of enhancer‐driven oncogene activation

International Journal of Cancer, EarlyView.
Abstract An aggressive subtype of acute myeloid leukemia (AML) is caused by enhancer hijacking resulting in MECOM overexpression. Several chromosomal rearrangements can lead to this: the most common (inv(3)/t(3;3)) results in a hijacked GATA2 enhancer, and there are several atypical MECOM rearrangements involving enhancers from other hematopoietic ...
Joyce Vriend, Ruud Delwel, Dorien Pastoors   +2 more
wiley   +1 more source

Correlation between malondialdehyde and metanephrine in patients with acute lymphoblastic leukemia

مجلة بغداد للعلوم, 2014
Acute lymphoblastic leukemia (ALL) is one of the most common diseases , so in this study the serum level of malondialdehyde and its relationship with metanephrine was investigated in acute lymphoblastic leukemia patients over one month of treatment. Some
Baghdad Science Journal
doaj   +1 more source

PROGNOSTIC FACTORS IN CHILDHOOD ACUTE LYMPHOBLASTIC LEUKEMIA (ALL) [PDF]

, 1977
Stephen E. Sallan, Bruce M. Camitta, Leonard Chess, David G. Nathan   +3 more
openalex   +1 more source

Targeting the Menin–KMT2A interaction in leukemia: Lessons learned and future directions

International Journal of Cancer, EarlyView.
Abstract Chromosomal rearrangements involving the Mixed Lineage Leukemia gene (MLL1, KMT2A) are defining a genetically distinct subset in about 10% of human acute leukemias. Translocations involving the KMT2A‐locus at chromosome 11q23 are resulting in the formation of a chimeric oncogene, where the N‐terminal part of KMT2A is fused to a variety of ...
Florian Perner, Jayant Y. Gadrey, Scott A. Armstrong, Michael W. M. Kühn   +3 more
wiley   +1 more source

601 IMMUNE STATUS OF CHILDREN WITH ACUTE LYMPHOBLASTIC LEUKEMIA (ALL) IN PROLONGED REMISSION (CR) [PDF]

, 1978
Nancy L. Dunn, Edward C. Russell, Thalachallour Mohanakumar, Nancy B. McWilliams, Harold M. Maurer   +4 more
openalex   +1 more source

Efficacy and Safety of the Third‐Generation Tyrosine Kinase Inhibitor Olverembatinib in Combination With Inotuzumab Ozogamicin for the Treatment of Adult Philadelphia Chromosome‐Positive Acute Lymphoblastic Leukemia Patients With Refractory/Relapsed Disease or Persistent Minimal Residual Disease Bridging to Hematopoietic Stem Cell Transplantation

American Journal of Hematology, EarlyView.
Xiaoyu Zhang, Yigeng Cao, Jialin Wei, Weihua Zhai, Qiaoling Ma, Chen Liang, Xin Chen, Wenbin Cao, Donglin Yang, Aiming Pang, Yi He, Sizhou Feng, Mingzhe Han, Rongli Zhang, Erlie Jiang   +14 more
wiley   +1 more source

Enhancer‐dependent gene regulation in space, time, and malignancies

International Journal of Cancer, EarlyView.
Abstract Control of cell‐type‐specific gene activation requires the coordinated activity of distal regulatory elements, including enhancers, whose inputs must be temporally integrated. Dysregulation of this regulatory capacity, such as aberrant usage of enhancers, can result in malignant transformation of cells.
Belinda Blum, Victoria Dachtler, Angelika Feldmann   +2 more
wiley   +1 more source

Leukocyte density and volume in normal subjects and in patients with acute lymphoblastic leukemia [PDF]

, 1976
Alvin Zipursky, E Bow, RS Seshadri, E J Brown   +3 more
openalex   +1 more source