Results 131 to 140 of about 555,062 (342)
Therapeutic targeting of chromatin alterations in leukemia and solid tumors
International Journal of Cancer, EarlyView.Abstract Alterations in chromatin conformation and post‐translational modification of histones have become increasingly recognized as critical drivers of cancer development, progression, and therapy resistance. Recent advances in drug development have led to the establishment of several highly selective small molecule inhibitors, several of which are ...
Florian Perner +7 more
wiley +1 more source
Editorial: Hematopoietic Stem Cell Theory in Relation to Possible Lymphoblastic Conversion of Chronic Myeloid Leukemia [PDF]
, 1974 Dane R. Boggs
openalex +1 more source
International Journal of Cancer, EarlyView.What's New? The rarity of acute lymphoblastic leukaemia and lack of available environmental data have made the role of environmental factors in genetic subtypes challenging to investigate. Here, the authors performed a CpG‐level analysis to investigate DNA methylation as an intermediate mechanism between environmental risk exposures and acute ...
Jessica R. Saville +5 more
wiley +1 more source
International Journal of Cancer, EarlyView.What's New? Infants born by cesarean section (CS) are at increased risk of certain long‐term adverse health outcomes, including childhood leukemia. The influence of maternal factors, pregnancy, and perinatal conditions on these associations, however, remains unclear.
Christina‐Evmorfia Kampitsi +4 more
wiley +1 more source
Subset derivation of T-cell acute lymphoblastic leukemia in man. [PDF]
, 1979 Ellis L. Reinherz +3 more
openalex +1 more source
CD86, the double agent: Significance of CD86 expression in B‐cell malignancies
International Journal of Cancer, EarlyView.Abstract Bypassing the anti‐tumor functions of the immune system is one of the keys to tumor survival. Tumors, especially hematological tumors, produce or express factors that retune T and B cells to inhibit the immune response. Coreceptors CD28 and CTLA‐4, and their ligands, CD80 and CD86, are involved in the immunological synapse and play an ...
Gábor Barna +4 more
wiley +1 more source
65. Blastogenesis of lymphocytes from different sources in acute lymphoblastic leukemia (ALL) of children [PDF]
, 1971 Massimo Lucarini +4 more
openalex +1 more source
International Journal of Cancer, EarlyView.What's New? Significant advances in childhood cancer survival have transformed outcomes for many children globally. However, emerging evidence suggests that, even in settings with universal healthcare, these gains are not equally distributed. Here, the authors focused on childhood cancer survival in Germany, using data from the German Childhood Cancer ...
Maike Wellbrock +7 more
wiley +1 more source
ACUTE LYMPHOBLASTIC LEUKEMIAS AND LYMPHOMAS OF CHILDHOOD WITH T CELL ORIGIN: CLINICAL FEATURES AND PROGNOSIS [PDF]
, 1974 John H. Kersey +3 more
openalex +1 more source
Long‐Term Follow‐up of CD19 CAR Therapy in Acute Lymphoblastic Leukemia
New England Journal of Medicine, 2018 Jae H. Park +14 more
semanticscholar +1 more source