Results 131 to 140 of about 139,045 (309)
Advancing Extracellular Vesicle Research: A Review of Systems Biology and Multiomics Perspectives
PROTEOMICS, EarlyView.ABSTRACT Extracellular vesicles (EVs) are membrane‐bound vesicles secreted by various cell types into the extracellular space and play a role in intercellular communication. Their molecular cargo varies depending on the cell of origin and its functional state.
Gloria Kemunto +2 more
wiley +1 more source
Precision Radiation Oncology, EarlyView.An elderly male patient with extramammary Paget disease of the scrotum and multiple metastases was treated with fractionated FLASH‐RT (40 Gy in 5 fractions) in the scrotal lesion. Abstract Objective Ultrahigh‐dose‐rate radiotherapy (FLASH‐RT) has been shown to reduce radiation‐induced normal tissue injury in preclinical studies.
Hui Luo +14 more
wiley +1 more source
Precision Radiation Oncology, EarlyView.• Objective: Assess helical Tomotherapy‐based TBI for clinical feasibility, dosimetric reproducibility, and in‐vivo accuracy using dual‐orientation simulation and patient‐specific QA. • Methodology: Implementation of ArcCHECK 3D diode array, ionization chamber verification, and in‐vivo dosimetry with OSLDs at 16 anatomical sites to ensure precise dose ...
Sandeep Singh +8 more
wiley +1 more source
Advances of target therapy on NOTCH1 signaling pathway in T-cell acute lymphoblastic leukemia [PDF]
, 2020 Ruyue Zheng +3 more
openalex +1 more source
Small Science, EarlyView.This review highlights recent advances in nanomedicine that enhance chimeric antigen receptor (CAR) T cell therapy against solid tumors. It discusses key barriers to CAR T cell efficacy and outlines nanotechnology‐based strategies to improve tumor targeting, remodel the immunosuppressive microenvironment, and integrate nanomaterials into CAR T cell ...
Stephen O’Rourke +3 more
wiley +1 more source
Simultaneous Occurrence of Advanced Neuroblastoma and Acute Lymphoblastic Leukemia: A Case Report
Middle East Journal of Cancer, 2011 Neuroblastoma is the most common extracranial solid tumor in children. The cooccurrence of neuroblastoma and acute lymphoblastic leukemia is rare. We report a rare case of advanced-stage neuroblastoma in a 3.5-year-old girl that was accompanied by acute ...
Kiavash Fekri +4 more
doaj
Small Methods, EarlyView.This work presents an integrated set of methods to evaluate the efficacy of asparaginase formulations against B‐cell Acute Lymphoblastic Leukemia (ALL) in mice, including the establishment of an ALL murine model, an amino acid depletion study using high‐performance liquid chromatography (HPLC), and comprehensive assessment of antibody production ...
Julien Santelli +6 more
wiley +1 more source
Small Methods, EarlyView.Recent advances in AI suggest the potential for stain‐free cell viability screening on brightfield microscopy images. However, no model has been reliably generalized across previously unseen cell types and compounds. Here, we show that “regularized imaging” of single cells in nanowells enables training of generalizable AI models for stain‐free ...
Pan Deng +4 more
wiley +1 more source