Results 141 to 150 of about 555,062 (342)

RepliChrom: Interpretable machine learning predicts cancer‐associated enhancer‐promoter interactions using DNA replication timing

iMeta, EarlyView.
RepliChrom is an interpretable machine learning model that predicts enhancer‐promoter interactions using DNA replication timing across multiple cell types. By integrating replication timing with chromatin interaction data from multiple experimental platforms, it accurately distinguishes true interactions and reveals promoter‐region signals as key ...
Fuying Dao, Benjamin Lebeau, Crystal Chia Yin Ling, Mi Yang, Xueqin Xie, Melissa Jane Fullwood, Hao Lin, Hao Lyu   +7 more
wiley   +1 more source

Efficacy and Toxicity Management of 19-28z CAR T Cell Therapy in B Cell Acute Lymphoblastic Leukemia

Science Translational Medicine, 2014
M. Davila, I. Rivière, Xiuyan Wang, S. Bartido, Jae H. Park, K. Curran, S. Chung, J. Stefanski, Oriana Bórquez-Ojeda, M. Olszewska, Jinrong Qu, Teresa Wasielewska, Q. He, Mitsú J. Fink, Himaly Shinglot, M. Youssif, M. Satter, Yongzeng Wang, James Hosey, Hilda Quintanilla, E. Halton, Y. Bernal, Diana C. G. Bouhassira, M. Arcila, M. Gonen, G. Roboz, P. Maslak, D. Douer, M. Frattini, S. Giralt, M. Sadelain, R. Brentjens   +31 more
semanticscholar   +1 more source

Patient‐derived xenograft models in pan‐cancer: From bench to clinic

Interdisciplinary Medicine, EarlyView.
Abstract Patient‐derived xenograft (PDX) models provide a robust preclinical platform that preserves the genetic and phenotypic heterogeneity of patient tumors while mirroring their tumor genetic characteristics, which retain malignant cells and the tumor pathological structure, making them valuable for studying tumor progression and developing ...
Jiatong Li, Ao Gu, Nannan Tang, Gokhan Zengin, Meng‐Yao Li, Yingbin Liu   +5 more
wiley   +1 more source

668 RECURRENCE OF PNEUMOCYSTIS CARINII PNEUMONIA IN PATIENTS WITH ACUTE LYMPHOBLASTIC LEUKEMIA [PDF]

, 1978
Kamran Tebbi, Samuel Gross
openalex   +1 more source

The Proteome of African Spitting and Non‐Spitting Cobra Venoms and Cytotoxicity Against Pancreatic Cancer Cells

Journal of Applied Toxicology, EarlyView.
ABSTRACT African cobra (Naja spp.) venom contains toxins dominated by proteins and peptides with inter‐ and intra‐specific variations. There are several FDA‐approved drugs from snake venom toxins from other regions, including South America and Asia. Profiling the proteomes of medically important African cobra venoms from different locations will aid in
Benedict C. Offor, Beric Muller, Lesetja R. Motadi, Lizelle A. Piater   +3 more
wiley   +1 more source

SERIAL ASSESSMENT OF BONE MARROW (BM) COLONY FORMING CAPACITY (CFC) IN CHILDREN WITH ACUTE LYMPHOBLASTIC LEUKEMIA (ALL) [PDF]

, 1977
Naomi L.C. Luban, Denis R. Miller
openalex   +1 more source

Blinatumomab versus Chemotherapy for Advanced Acute Lymphoblastic Leukemia

New England Journal of Medicine, 2017
H. Kantarjian, A. Stein, N. Gökbuget, A. Fielding, A. Schuh, J. Ribera, A. Wei, H. Dombret, R. Foà, R. Bassan, Ö. Arslan, M. Sanz, J. Bergeron, F. Demirkan, E. Lech-Maranda, A. Rambaldi, X. Thomas, H. Horst, M. Brüggemann, W. Klapper, B. Wood, A. Fleishman, D. Nagorsen, C. Holland, Z. Zimmerman, M. Topp   +25 more
semanticscholar   +1 more source

Four Pharmacogenomic Variants Strongly Linked to Corticosteroid‐Induced Avascular Necrosis in Children with Cancer

The Journal of Clinical Pharmacology, EarlyView.
Abstract Corticosteroids are effective anti‐cancer agents for treating hematologic malignancies in children. However, avascular necrosis (AVN) is a common and debilitating adverse effect, leading to bone death and impacting long‐term quality of life. This study aimed to uncover the genetic factors contributing to corticosteroid‐induced AVN in a well ...
Miguel Cordova‐Delgado, Erika N. Scott, Shahrad R. Rassekh, Catrina M. Loucks, Wan‐Chun Chang, Edward J. Raack, Jessica N. Trueman, Colin J. D. Ross, Bruce C. Carleton, the Canadian Pharmacogenomics Network for Drug Safety Consortium   +9 more
wiley   +1 more source

Acute and long-term neurological complications in children with acute lymphoblastic leukemia

, 1970
Asifur Rahman, M. A. Mannan, Samia Sadeque   +2 more
openalex   +2 more sources

Interrelationship of immunologic characteristics, proliferation pattern, and prednisone sensitivity in acute lymphoblastic leukemia of childhood [PDF]

, 1979
JA Bakkeren, GA de Vaan, HF Hillen
openalex   +1 more source