Results 171 to 180 of about 577,742 (361)

CRISPR/Cas9‐edited tumor‐associated immune cells in cancer immunotherapy

VIEW, EarlyView.
Abstract Immuno‐oncology represents an emerging field that has significantly transformed tumor therapeutics, with immune cells serving as the cellular foundations of cancer immunotherapy. Due to its high efficiency and sensitivity, CRISPR/Cas9 genome editing is a highly promising technique for precise and rapid gene modification.
Yuhui Ma, Junxin Chen, Yuan Du, Zhihao Cao, Weizhi Ji, Yuyu Niu, Zebin Yang   +6 more
wiley   +1 more source

Treatment of acute lymphoblastic leukemia in adults with intensive induction, consolidation, and maintenance chemotherapy [PDF]

, 1989
KK Hussein, Steve Dahlberg, David Head, Waddell Cc, Lyubica Dabich, Weick Jk, F Morrison, Saiki Jh, Earl N. Metz, S E Rivkin   +9 more
openalex   +1 more source

Blinatumomab for minimal residual disease in adults with B-cell precursor acute lymphoblastic leukemia.

Blood, 2018
N. Gökbuget, H. Dombret, M. Bonifacio, A. Reichle, C. Graux, C. Faul, H. Diedrich, M. Topp, M. Brüggemann, H. Horst, V. Havelange, J. Stieglmaier, Hendrik Wessels, V. Haddad, J. Benjamin, G. Zugmaier, D. Nagorsen, R. Bargou   +17 more
semanticscholar   +1 more source

Silibinin‐driven microbial and metabolic reprogramming restores CD4+ T cell immunity in HIV immunological nonresponders

VIEW, EarlyView.
Despite efficacious antiretroviral therapy, 10%–40% of HIV‐infected individuals exhibit inadequate immune reconstitution due to persistent inflammatory activation and NAD+ metabolic dysregulation—a critical cofactor in cellular bioenergetics. We administered silibinin to 53 HIV immunological non‐responders and elucidated its mechanism through selective
Wenli Liu, Minghui An, Qi Wang, Yuxin Shang, Shuyao Zang, Haibo Ding, Shuai Fu, Yun Liu, Xue Dong, Xiao Yang, Jinna Dai, Xiaoxu Han, Yingchun Xu, Hong Shang   +13 more
wiley   +1 more source

Identification of Predictive Biomarkers for Cytokine Release Syndrome after Chimeric Antigen Receptor T-cell Therapy for Acute Lymphoblastic Leukemia.

Cancer Discovery, 2016
D. Teachey, D. Teachey, S. Lacey, P. Shaw, J. Melenhorst, S. Maude, N. Frey, E. Pequignot, V. Gonzalez, Fang Chen, J. Finklestein, D. Barrett, S. Weiss, J. Fitzgerald, R. Berg, R. Aplenc, C. Callahan, S. Rheingold, Zhaohui Zheng, S. Rose-John, J. White, Farzana Nazimuddin, G. Wertheim, B. Levine, C. June, D. Porter, S. Grupp   +26 more
semanticscholar   +1 more source

Adult Acute Lymphoblastic Leukemia

Definitions, 2020

semanticscholar   +1 more source

Imaging of Abdominal Complications in Children With Acute Lymphoblastic Leukaemia

Journal of Medical Imaging and Radiation Oncology, EarlyView.
ABSTRACT Acute lymphoblastic leukaemia (ALL) is the most common paediatric malignancy and remains one of the most common causes of cancer‐related death in children and adolescents. Five‐year overall survival rates now exceed 90% with current multidrug chemotherapeutic regimens. This improvement, coupled with the toxicity of chemotherapy, has led to the
Luke R. Holmes, Rishi S. Kotecha, Derek J. Roebuck   +2 more
wiley   +1 more source

Therapy of acute lymphoblastic leukemia in childhood [PDF]

, 1980
AM Mauer
openalex   +1 more source

Clinical validation of the nursing diagnosis of inadequate nutritional intake in children with cancer

International Journal of Nursing Knowledge, EarlyView.
Abstract Purpose To clinically validate the nursing diagnosis “Inadequate Nutritional Intake” based on elements identified within a specific situation theory framework in the context of children with cancer. Methods This is a diagnostic accuracy study following the Standards for Reporting Diagnostic Accuracy Studies (STARD) protocol.
Iane Ximenes Teixeira, Natália Cabrera Matos, Marcos Venícios de Oliveira Lopes, Viviane Martins da Silva, Amanda Laryssa Gomes do Nascimento, Yanka Alcântara Cavalcante, Ana Beatriz Oliveira Marques dos Santos, Daniele Paula Alves Mouta   +7 more
wiley   +1 more source

Activity of a specific inhibitor of the BCR-ABL tyrosine kinase in the blast crisis of chronic myeloid leukemia and acute lymphoblastic leukemia with the Philadelphia chromosome.

New England Journal of Medicine, 2001
B. Druker, C. Sawyers, H. Kantarjian, D. Resta, Sofia Fernandes Reese, J. Ford, R. Capdeville, M. Talpaz   +7 more
semanticscholar   +1 more source