Results 231 to 240 of about 230,151 (306)

Clinical Impact of Immunoglobulin Heavy Chain Clonality in Pediatric B-Cell Precursor Acute Lymphoblastic Leukemia. [PDF]

open access: yesCancer Med
Katai Y   +11 more
europepmc   +1 more source

Efficacy of Endoscopic Ultrasound‐guided Transluminal Drainage Using Lumen‐apposing Metal Stents for the Treatment of Pancreatic Fluid Collections

open access: yesDEN Open, Volume 6, Issue 1, April 2026.
ABSTRACT Objectives Pancreatic fluid collections (PFCs) are able to develop secondary to either fluid leakage or liquefaction of acute pancreatitis, chronic pancreatitis, pancreatic trauma, or after pancreatic surgery. While most PFCs resolve spontaneously, endoscopic procedures are sometimes necessary.
Keisuke Kinoshita   +17 more
wiley   +1 more source

Mechanisms of enhancer‐driven oncogene activation

open access: yesInternational Journal of Cancer, Volume 158, Issue 2, Page 333-341, 15 January 2026.
Abstract An aggressive subtype of acute myeloid leukemia (AML) is caused by enhancer hijacking resulting in MECOM overexpression. Several chromosomal rearrangements can lead to this: the most common (inv(3)/t(3;3)) results in a hijacked GATA2 enhancer, and there are several atypical MECOM rearrangements involving enhancers from other hematopoietic ...
Joyce Vriend   +2 more
wiley   +1 more source

Targeting the Menin–KMT2A interaction in leukemia: Lessons learned and future directions

open access: yesInternational Journal of Cancer, Volume 158, Issue 2, Page 342-356, 15 January 2026.
Abstract Chromosomal rearrangements involving the Mixed Lineage Leukemia gene (MLL1, KMT2A) are defining a genetically distinct subset in about 10% of human acute leukemias. Translocations involving the KMT2A‐locus at chromosome 11q23 are resulting in the formation of a chimeric oncogene, where the N‐terminal part of KMT2A is fused to a variety of ...
Florian Perner   +3 more
wiley   +1 more source

Improving pain management for murine orthotopic xenograft models of acute lymphoblastic leukemia. [PDF]

open access: yesLab Anim (NY)
Schreiber T   +9 more
europepmc   +1 more source

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