Results 241 to 250 of about 230,151 (306)

A combination of artemisinin, moxidectin, and doxorubicin drugs can selectively and efficiently induce apoptosis in acute lymphoblastic and chronic myeloid leukemia cells in vitro and ex vivo [PDF]

Viviana Soto-Mercado, Miguel Mendivil-Perez, Marlene Jimenez-Del-Rio, Carlos Velez-Pardo   +3 more
openalex   +1 more source

Enhancer‐dependent gene regulation in space, time, and malignancies

International Journal of Cancer, Volume 158, Issue 2, Page 357-367, 15 January 2026.
Abstract Control of cell‐type‐specific gene activation requires the coordinated activity of distal regulatory elements, including enhancers, whose inputs must be temporally integrated. Dysregulation of this regulatory capacity, such as aberrant usage of enhancers, can result in malignant transformation of cells.
Belinda Blum, Victoria Dachtler, Angelika Feldmann   +2 more
wiley   +1 more source

Global burden of acute lymphoblastic leukemia following the COVID-19 pandemic. [PDF]

Ann Hematol
Fan H, Yang Y, Lu Y, Li J, Huang Z, Ren Z, Zhou B.   +6 more
europepmc   +1 more source

Therapeutic targeting of chromatin alterations in leukemia and solid tumors

International Journal of Cancer, Volume 158, Issue 2, Page 382-408, 15 January 2026.
Abstract Alterations in chromatin conformation and post‐translational modification of histones have become increasingly recognized as critical drivers of cancer development, progression, and therapy resistance. Recent advances in drug development have led to the establishment of several highly selective small molecule inhibitors, several of which are ...
Florian Perner, Tobias Berg, Daniel Sasca, Sophie‐Luise Mersiowsky, Jayant Y. Gadrey, Johanna Thomas, Michael W. M. Kühn, Michael Lübbert   +7 more
wiley   +1 more source

Combination of targeted pharmacotherapy and immunotherapy with anti-CD19 CAR NK cells in acute lymphoblastic leukemia. [PDF]

Hemasphere
Kirchhoff H, Schoenherr C, Fleischer L, Schweighart EK, Esser R, Talbot SR, Schambach A, Koehl U, Heidenreich O, Eder M, Scherr M.   +10 more
europepmc   +1 more source

Reduced cardiorespiratory fitness in adult survivors of childhood acute lymphoblastic leukemia

, 2013
Emily S. Tonorezos, P. G. Snell, Chaya S. Moskowitz, Debra Eshelman‐Kent, Jennifer E. Liu, Joanne F. Chou, Stephanie M. Smith, Andrea L. Dunn, Timothy S. Church, Kevin C. Oeffinger   +9 more
openalex   +1 more source

Allogeneic Hematopoietic Stem Cell Transplantation in Adolescents and Young Adults With Acute Lymphoblastic Leukemia—A Retrospective, Dual‐Center Study

American Journal of Hematology, Volume 101, Issue 1, Page 16-25, January 2026.
ABSTRACT Survival outcomes for adolescents and young adults (AYAs) with acute lymphoblastic leukemia (ALL) have improved with modern frontline therapies and minimal residual disease (MRD)‐guided strategies. As a result, allogeneic hematopoietic cell transplantation (HCT) is increasingly deferred in first remission (CR1) and used in the relapsed setting.
Oren Pasvolsky, Shai Shimony, Rima M. Saliba, Curtis Marcoux, Celina Ledesma, Gabriela Rondon, Priti Tewari, Dristhi Ragoonanan, Nicholas J. Short, Elias Jabbour, Mahasweta Gooptu, Vincent T. Ho, Robert J. Soiffer, Joseph H. Antin, John Koreth, Corey S. Cutler, Jonathan D. Paolino, Christine N. Duncan, Leslie E. Lehmann, Daniel J. DeAngelo, Nitin Jain, Richard Champlin, Elizabeth Shpall, Marlise R. Luskin, Partow Kebriaei   +24 more
wiley   +1 more source

Management of relapsed acute lymphoblastic leukemia in a patient with down syndrome: A case report. [PDF]

Leuk Res Rep
Almatar E, Alsharidah S, Hashem OA.
europepmc   +1 more source

Optimizing Asparaginase Treatment for Adolescent and Young Adult (AYA) Patients With Acute Lymphoblastic Leukemia: US Consensus Panel Recommendations

American Journal of Hematology, Volume 101, Issue 1, Page 41-55, January 2026.
ABSTRACT Asparaginase is an integral component of therapy for pediatric patients with acute lymphoblastic leukemia/lymphoblastic lymphoma. The success of asparaginase‐containing regimens has led to trials of pediatric/pediatric‐inspired regimens incorporating asparaginase for treating adolescent and young adult (AYA) and adult populations with acute ...
Ibrahim Aldoss, Amir Ali, Ryan D. Cassaday, Emily K. Curran, Marlise R. Luskin, Luke D. Maese, Etan Orgel, Dan Douer   +7 more
wiley   +1 more source

Cortical morphological alterations and structural covariant network topology changes in children with acute lymphoblastic leukemia. [PDF]

Quant Imaging Med Surg
Wei K, Chen R, Gao Z, Mai H, Liu L, Cao W.   +5 more
europepmc   +1 more source