Results 261 to 270 of about 230,151 (306)

Clinical and genetic features of multiple primary tumours cohorts with a renal cell carcinoma: Implications for molecular genetic investigations

open access: yesInternational Journal of Cancer, Volume 157, Issue 12, Page 2532-2543, 15 December 2025.
What's New? Current knowledge of the genetic architecture underlying the development of renal cell carcinoma‐related multiple primary tumours is limited. The authors comprehensively analysed the results of exome/genome sequencing cohorts including 534 patients to better define genotype–phenotype correlations.
Huairen Zhang   +6 more
wiley   +1 more source

V-H gene usage differs in germline and mutated B-cell chronic lymphocytic leukemia [PDF]

open access: yes, 2003
Amlot, P   +8 more
core  

Germline variants observed in pediatric cancer patients related to hereditary breast and ovarian cancer in adults

open access: yesInternational Journal of Cancer, Volume 157, Issue 12, Page 2447-2454, 15 December 2025.
What's New? Investigating the spectrum of (likely) pathogenic germline variants (LP/PVs) in hereditary breast and ovarian cancer (HBOC) genes in pediatric malignancies by unselected genotyping identified 44% (12/27) of clinically unsuspected cases. Burden testing demonstrated considerable associations between monoallelic LP/PVs in five HBOC genes and ...
Katharina Daugs   +11 more
wiley   +1 more source

AKT regulation of oncogenic Notch pathway in T-cell acute lymphoblastic leukemia

open access: green, 2015
Natalia Platonova   +10 more
openalex   +1 more source

Risk Factors for and Impact of Pre‐Engraftment Syndrome on Outcomes Following Single‐Unit Cord Blood Transplantation in Adults

open access: yesAmerican Journal of Hematology, Volume 100, Issue 12, Page 2248-2260, December 2025.
ABSTRACT Pre‐engraftment syndrome (PES) is a unique complication of cord blood transplantation (CBT) whose risk factors and impact on transplant outcomes remain controversial. Using a nationwide database in Japan, we analyzed a total of 3734 patients who underwent single‐unit CBT.
Masatoshi Sakurai   +27 more
wiley   +1 more source

From Gene to Enzyme: Multidimensional Decoding of the GGT Molecular Family and Its Clinical Tumor Diagnosis

open access: yesCancer Medicine, Volume 14, Issue 23, December 2025.
ABSTRACT Background Gamma‐glutamyltransferase (GGT) is a membrane‐bound enzyme involved in glutathione metabolism and oxidative stress regulation. Although it is traditionally viewed as a liver function marker, emerging evidence suggests that its aberrant expression is closely associated with tumorigenesis, progression, and therapeutic resistance ...
Fei Wang   +11 more
wiley   +1 more source

A New Histology-Based Prognostic Index for Acute Lymphoblastic Leukemia (Urayasu Classification for ALL) and a Review of the Literature on Drug Resistance Induced by Functional Proteins in Hematologic Malignancies

open access: green
Toru Mitsumori   +14 more
openalex   +1 more source

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