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Asparaginase in Acute Lymphoblastic Leukemia
Clinical Lymphoma Myeloma and Leukemia, 2014Cure rates in pediatric acute lymphoblastic leukemia have significantly improved over the past decades. Now, almost 90% of children will survive the disease. The cure rates in adolescents, young adults, and adults have not kept pace with the improvements in younger patients, even though almost an equal proportion of adult patients achieve complete ...
Michael Rytting, Jitesh D. Kawedia
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Pharmacogenomics in acute lymphoblastic leukemia
Best Practice & Research Clinical Haematology, 2017Pharmacogenomics is a fast-growing field of personalized medicine using a patient's genomic profile to determine drug disposition or response to drug therapy, in order to develop safer and more effective pharmacotherapy. Childhood acute lymphoblastic leukemia (ALL), being the most common malignancy in childhood, which is treated with uniform and ...
Shawn H.R. Lee, Jun J. Yang
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Preleukemia in Acute Lymphoblastic Leukemia
Acta Haematologica, 1981A patient who presented with preleukemia evolving into acute lymphoblastic leukemia is described. The preleukemic phase was characterized by a positive acidified serum lysis test (Ham test).
I. Ariel +2 more
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2007
Acute lymphoblastic leukemias (ALLs) are a group of hematological neoplasias defined by cytomorphology, cytochemistry, immunological markers, and more recently, molecular markers. The prognosis of ALL has much improved in the last 30 yr, especially in the age group between 2 and 10 yr, where most patients can be cured by chemotherapy.
Vishwas S. Sakhalkar, Reinhold Munker
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Acute lymphoblastic leukemias (ALLs) are a group of hematological neoplasias defined by cytomorphology, cytochemistry, immunological markers, and more recently, molecular markers. The prognosis of ALL has much improved in the last 30 yr, especially in the age group between 2 and 10 yr, where most patients can be cured by chemotherapy.
Vishwas S. Sakhalkar, Reinhold Munker
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Activating Mutations of NOTCH1 in Human T Cell Acute Lymphoblastic Leukemia
Science, 2004A. Weng +8 more
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Acute Lymphoblastic Leukemia in Children and Adolescents
The EBMT Handbook, 2018Christina Peters +2 more
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Acute lymphoblastic leukemia in adults
Current Treatment Options in Oncology, 2000The therapy of acute lymphoblastic leukemia (ALL) in adults has built on the remarkable success achieved in the treatment of this disease in children. However, older age and other adverse risk factors seen more commonly in adults than in children have lessened the success of the treatment of ALL in comparison with what has been achieved in children ...
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Acute Lymphoblastic Leukemia of Childhood
Hematology/Oncology Clinics of North America, 1987Over the last 20 years, the rate of long-term disease-free survival of childhood acute lymphoblastic leukemia increased from less than 1 to 60 per cent. Strategies for disease control include (1) intensive multiagent induction to rapidly decrease the tumor burden and minimize the chance of emergence of a resistant population of cells, (2) restoration ...
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Critical care management of chimeric antigen receptor T‐cell therapy recipients
Ca-A Cancer Journal for Clinicians, 2022Alexander Shimabukuro-Vornhagen +2 more
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