Results 321 to 330 of about 555,062 (342)
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Childhood acute lymphoblastic leukemia
Reviews in Clinical and Experimental Hematology, 2002As cure rates in childhood acute lymphoblastic leukemia reach 80%, emphasis is increasingly placed on the accurate identification of drug‐resistant cases, the elucidation of the mechanisms involved in drug resistance and the development of new therapeutic strategies targeted toward the pivotal molecular lesions.
Mary V. Relling +3 more
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Childhood Acute Lymphoblastic Leukemia
Pediatric Annals, 1988Acute lymphoblastic leukemia accounts for 80% of leukemia in children. The exact cause is unknown, but some genetic, immunologic, viral, and environmental factors have been implicated. Symptoms at the time of diagnosis frequently include fever, bleeding, fatigue, and irritability. Initial white blood cell count and patient age at diagnosis are the most
Carol Diamond, Katherine K Matthay
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Acute lymphoblastic leukemia in the elderly
European Journal of Haematology, 1990We report our findings in 18 patients with acute lymphoblastic leukemia (ALL) aged 60 years or older. A preleukemic syndrome was observed in 2 patients. Compared to younger adults with ALL, L3 morphology was unexpectedly frequent (4/16) T‐ALL was not observed. Other criteria of poor prognosis (high white blood cell count, CNS involvement, organomegaly,
Delannoy, André +7 more
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2007
Acute lymphoblastic leukemias (ALLs) are a group of hematological neoplasias defined by cytomorphology, cytochemistry, immunological markers, and more recently, molecular markers. The prognosis of ALL has much improved in the last 30 yr, especially in the age group between 2 and 10 yr, where most patients can be cured by chemotherapy.
Vishwas S. Sakhalkar, Reinhold Munker
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Acute lymphoblastic leukemias (ALLs) are a group of hematological neoplasias defined by cytomorphology, cytochemistry, immunological markers, and more recently, molecular markers. The prognosis of ALL has much improved in the last 30 yr, especially in the age group between 2 and 10 yr, where most patients can be cured by chemotherapy.
Vishwas S. Sakhalkar, Reinhold Munker
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Preleukemia in Acute Lymphoblastic Leukemia
Acta Haematologica, 1981A patient who presented with preleukemia evolving into acute lymphoblastic leukemia is described. The preleukemic phase was characterized by a positive acidified serum lysis test (Ham test).
I. Ariel +2 more
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Activating Mutations of NOTCH1 in Human T Cell Acute Lymphoblastic Leukemia
Science, 2004A. Weng +8 more
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Acute Lymphoblastic Leukemia of Childhood
Hematology/Oncology Clinics of North America, 1987Over the last 20 years, the rate of long-term disease-free survival of childhood acute lymphoblastic leukemia increased from less than 1 to 60 per cent. Strategies for disease control include (1) intensive multiagent induction to rapidly decrease the tumor burden and minimize the chance of emergence of a resistant population of cells, (2) restoration ...
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Acute Lymphoblastic Leukemia in Children and Adolescents
The EBMT Handbook, 2018Christina Peters +2 more
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Acute lymphoblastic leukemia in adults
Current Treatment Options in Oncology, 2000The therapy of acute lymphoblastic leukemia (ALL) in adults has built on the remarkable success achieved in the treatment of this disease in children. However, older age and other adverse risk factors seen more commonly in adults than in children have lessened the success of the treatment of ALL in comparison with what has been achieved in children ...
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