Results 31 to 40 of about 555,062 (342)

Inotuzumab Ozogamicin versus Standard Therapy for Acute Lymphoblastic Leukemia.

New England Journal of Medicine, 2016
BACKGROUND The prognosis for adults with relapsed acute lymphoblastic leukemia is poor. We sought to determine whether inotuzumab ozogamicin, an anti-CD22 antibody conjugated to calicheamicin, results in better outcomes in patients with relapsed or ...
H. Kantarjian, D. DeAngelo, M. Stelljes, G. Martinelli, M. Liedtke, W. Stock, N. Gökbuget, S. O'brien, Kongming Wang, Tao Wang, M. L. Paccagnella, B. Sleight, E. Vandendries, A. Advani   +13 more
semanticscholar   +1 more source

Asparagine Synthetase in Cancer: Beyond Acute Lymphoblastic Leukemia

Frontiers in Oncology, 2020
Asparagine Synthetase (ASNS) catalyzes the synthesis of the non-essential amino acid asparagine (Asn) from aspartate (Asp) and glutamine (Gln). ASNS expression is highly regulated at the transcriptional level, being induced by both the Amino Acid ...
Martina Chiu, G. Taurino, M. Bianchi, M. Kilberg, O. Bussolati   +4 more
semanticscholar   +1 more source

B-Acute Lymphoblastic Leukemia/Lymphoblastic Lymphoma [PDF]

American Journal of Clinical Pathology, 2015
This session of the 2013 Society of Hematopathology/European Association for Haematopathology Workshop was dedicated to B-acute lymphoblastic leukemia (B-ALL)/lymphoblastic lymphoma (LBL) with recurrent translocations and not otherwise specified.In this review, we summarize the cases discussed during the workshop, review the pertinent and most recent ...
Jeffrey L. Jorgensen, Sanam Loghavi, Jeffery L. Kutok   +2 more
openaire   +3 more sources

Attenuated measles virus controls pediatric acute B-lineage lymphoblastic leukemia in NOD/SCID mice

Haematologica, 2014
Novel therapies are needed for pediatric acute lymphoblastic leukemia resistant to conventional therapy. While emerging data suggest leukemias as possible targets of oncolytic attenuated measles virus, it is unknown whether measles virus can eradicate ...
Nike C. Lühl, Felix Zirngibl, Carmen Dorneburg, Jiwu Wei, Meike Dahlhaus, Thomas F.E. Barth, Lüder H. Meyer, Manon Queudeville, Sarah Eckhoff, Klaus-Michael Debatin, Christian Beltinger   +10 more
doaj   +1 more source

Acute lymphoblastic leukemia: a comprehensive review and 2017 update

Blood Cancer Journal, 2017
Acute lymphoblastic leukemia (ALL) is the second most common acute leukemia in adults, with an incidence of over 6500 cases per year in the United States alone.
T. Terwilliger, M. Abdul-Hay
semanticscholar   +1 more source

Precision medicine in acute lymphoblastic leukemia

Frontiers in Medicine, 2020
The cure rate of childhood acute lymphoblastic leukemia (ALL) has exceeded 90% in some contemporary clinical trials. However, the dose intensity of conventional chemotherapy has been pushed to its limit.
C. Pui
semanticscholar   +1 more source

A case report of secondary B-cell acute lymphoblastic leukemia treated with a combination of FLT3 inhibitor and decitabine

Frontiers in Oncology
Secondary acute lymphoblastic leukemia (s-ALL) refers to acute lymphoblastic leukemia that occurs after a previous malignant tumor, including therapy-related acute lymphoblastic leukemia (t-ALL) and prior malignant tumor acute lymphoblastic leukemia (pm ...
Mengci Hu, Wenzhe Li, Pan Li, Jie Tan, Ya Wang, Ya Wang   +5 more
doaj   +1 more source

A case of therapy-related acute lymphoblastic leukemia following the treatment of acute myeloid leukemia

Leukemia Research Reports, 2022
Therapy-related acute lymphoblastic leukemia represents a distinct entity associated with inferior survival compared with de novo acute lymphoblastic leukemia.
Sufana Shikdar, Yuan Ying, Mohamad Khawandanah   +2 more
doaj  

Prognostic implications of mutations and expression of the Wilms tumor 1 (WT1) gene in adult acute T-lymphoblastic leukemia

Haematologica, 2010
Background The role of the Wilms tumor 1 gene (WT1) in acute leukemias has been underscored by mutations found in acute myeloid leukemia identifying patients with inferior survival.
Sandra Heesch, Nicola Goekbuget, Andrea Stroux, Jutta Ortiz Tanchez, Cornelia Schlee, Thomas Burmeister, Stefan Schwartz, Olga Blau, Ulrich Keilholz, Antonia Busse, Dieter Hoelzer, Eckhard Thiel, Wolf-Karsten Hofmann, Claudia D. Baldus   +13 more
doaj   +1 more source

Acute Lymphoblastic Leukemia [PDF]

Journal of the National Comprehensive Cancer Network, 2012
The inaugural NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines) for acute lymphoblastic leukemia (ALL) were developed as a result of meetings convened by a multi-disciplinary panel of experts in 2011. These NCCN Guidelines provide recommendations on the diagnostic evaluation and workup for ALL, risk assessment, risk-stratified treatment ...
Naresh Bellam, Michael Millenson, Geoffrey L. Uy, Lloyd E. Damon, Meir Wetzler, Kristina M. Gregory, Stephanie A. Terezakis, Steven Coutre, Patricia Aoun, Arati V. Rao, Susan O'Brien, Maoko Naganuma, Jennifer Cultrera, Joseph C. Alvarnas, Hetty E. Carraway, Michael Boyer, Daniel J. DeAngelo, Peter F. Coccia, Salil Goorha, Dan Douer, Stephen H. Petersdorf, William Blum, Olga Frankfurt, Patrick A. Brown, Andrew D. Zelenetz, Karen K. Ballen, Haydar Frangoul   +26 more
openaire   +3 more sources