Results 81 to 90 of about 577,742 (361)

A Retrospective Survey of Molecular, Cytogenetic, and Immunophenotype Data of Patients with Acute Lymphoblastic Leukemia in Northeast Iran [PDF]

open access: yesMiddle East Journal of Cancer, 2019
Background: Excess proliferation of blood cells may lead to leukemia, which is associated with structural and numerical chromosomal aberrations. Cytogenetic findings of acute lymphoblastic leukemia can be applicable in diagnosis, prognosis, and treatment
Seyyede Fatemeh Shams   +5 more
doaj   +1 more source

Cytokine Release Syndrome Grade as a Predictive Marker for Infections in Patients With Relapsed or Refractory B-Cell Acute Lymphoblastic Leukemia Treated With Chimeric Antigen Receptor T Cells

open access: yesClinical Infectious Diseases, 2018
Cytokine release syndrome grade 3 or higher was independently associated with increased risk of subsequent infection and in particular with bloodstream infection in patients with relapsed B-cell acute lymphoblastic leukemia treated with CD19 chimeric ...
J. H. Park   +12 more
semanticscholar   +1 more source

AP2M1 Amplification Orchestrates Notch‐Mediated Chemoresistance in Hematopoietic Stem Cells of Acute Myeloid Leukemia Patients

open access: yesAdvanced Science, EarlyView.
The precise regulation of AP2M1 is essential for normal hematopoiesis. Overexpression of AP2M1 negatively affects the clinical outcomes of AML patients. Upregulation of AP2M1 enhances stemness and chemoresistance in HSPC cells of AML. AP2M1 modulates NOTCH1 expression, enhancing the Notch1 signaling pathway.
Hansong Lee   +28 more
wiley   +1 more source

Acute lymphoblastic leukemia of childhood presenting as aplastic anemia: report of two cases

open access: yesRevista Brasileira de Hematologia e Hemoterapia, 2012
Acute lymphoblastic leukemia is the most common malignancy in pediatric patients; its diagnosis is usually easy to establish as malignant lymphoblasts invade the bone marrow and peripheral blood.
Laura Villarreal-Martínez   +4 more
doaj   +1 more source

Molecular diagnosis of lymphoblastic leukemia

open access: yesJournal of Cancer Research and Therapeutics, 2013
The mixed lineage leukemia (MLL) gene at chromosome band 11q23 is commonly involved in reciprocal translocations that is detected in acute leukemia. The MLL gene, commonly known as mixed lineage leukemia or myeloid lymphoid leukemia, has been independently identified and cloned from the 11q23 breakpoint of acute leukemia.
Seetha Dayakar   +5 more
openaire   +3 more sources

Classification of acute lymphoblastic leukemia using deep learning

open access: yesMicroscopy research and technique (Print), 2018
Acute Leukemia is a life‐threatening disease common both in children and adults that can lead to death if left untreated. Acute Lymphoblastic Leukemia (ALL) spreads out in children's bodies rapidly and takes the life within a few weeks.
A. Rehman   +5 more
semanticscholar   +1 more source

Risk Factors for and Impact of Pre‐Engraftment Syndrome on Outcomes Following Single‐Unit Cord Blood Transplantation in Adults

open access: yesAmerican Journal of Hematology, EarlyView.
ABSTRACT Pre‐engraftment syndrome (PES) is a unique complication of cord blood transplantation (CBT) whose risk factors and impact on transplant outcomes remain controversial. Using a nationwide database in Japan, we analyzed a total of 3734 patients who underwent single‐unit CBT.
Masatoshi Sakurai   +27 more
wiley   +1 more source

Marrow transplantation for patients with acute lymphoblastic leukemia in remission [PDF]

open access: bronze, 1979
ED Thomas   +9 more
openalex   +3 more sources

How I Treat Newly Diagnosed T-cell Acute Lymphoblastic Leukemia (T-ALL) and T-cell Lymphoblastic Lymphoma in Children.

open access: yesBlood, 2019
T-cell acute lymphoblastic leukemia (T-ALL) is an aggressive malignancy that has historically been associated with a very poor prognosis. Nevertheless, despite a lack of incorporation of novel agents, the development of intensified T-ALL focused ...
D. Teachey, D. O’Connor
semanticscholar   +1 more source

Allogeneic Hematopoietic Stem Cell Transplantation in Adolescents and Young Adults With Acute Lymphoblastic Leukemia—A Retrospective, Dual‐Center Study

open access: yesAmerican Journal of Hematology, EarlyView.
ABSTRACT Survival outcomes for adolescents and young adults (AYAs) with acute lymphoblastic leukemia (ALL) have improved with modern frontline therapies and minimal residual disease (MRD)‐guided strategies. As a result, allogeneic hematopoietic cell transplantation (HCT) is increasingly deferred in first remission (CR1) and used in the relapsed setting.
Oren Pasvolsky   +24 more
wiley   +1 more source

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