Expression of A-myb, but not c-myb and B-myb, is restricted to Burkitt's lymphoma, sIg+ B-acute lymphoblastic leukemia, and a subset of chronic lymphocytic leukemias [PDF]
, 1996 Josée Golay +12 more
openalex +1 more source
Are we ignoring sex differences in haematological malignancies? A call for improved reporting
British Journal of Haematology, EarlyView.A large body of data indicates that there are sex differences in the incidence of haematological malignancies, their clinical presentation and molecular profiles, and possibly also their aetiologies. Furthermore, sex‐related differences exist in treatment tolerability and outcomes.
Ora Paltiel +2 more
wiley +1 more source
British Journal of Haematology, EarlyView.Using current standard‐of‐care tests used in clinical practice, 20%–30% of B‐cell precursor acute lymphoblastic leukaemia (BCP‐ALL) patients remain unclassified. These patients are grouped into a heterogeneous category named B‐other ALL and are all treated with the same intensity. The application of RNA‐seq, together with the integration of standard‐of‐
Clara Vicente‐Garcés +12 more
wiley +1 more source
Development and Validation of a Quantitative Polymerase Chain Reaction Assay to Evaluate Minimal Residual Disease for T-Cell Acute Lymphoblastic Leukemia and Follicular Lymphoma [PDF]
, 1999 Gregory A. Hosler +4 more
openalex +1 more source
Anaplastic large cell lymphoma in children and adolescents
British Journal of Haematology, EarlyView.Summary Anaplastic lymphoma kinase (ALK)‐positive anaplastic large‐cell lymphoma (ALCL) accounts for >95% of ALCL cases in children and adolescents. The first description of ALCL as a CD30‐positive lymphoma in 1985 was followed by the detection of chromosomal translocations involving the ALK gene at chromosome 2p23.
Eric J. Lowe, Wilhelm Woessmann
wiley +1 more source
B‐lineage lymphoblastic lymphoma is a clinicopathologic entity distinct from other histologically similar aggressive lymphomas with blastic morphology [PDF]
, 1999 Robert A. Soslow +2 more
openalex +1 more source
Cancer‐Type‐Specific DNA Methylation Is a Source of Vulnerability in Liver Cancer Cells
Cancer Science, EarlyView.We profiled genome‐wide DNA methylation in 1165 human cancer cell lines representing 25 cancer types and identified 73 genes as potential liver cancer‐specific methylation‐silenced genes. We selected ASNS, BCAT2, FXYD5, and NQO1 genes for further experimental analysis and demonstrated that aberrant methylation of BCAT2 contributes to the vulnerability ...
Karen Minowa +3 more
wiley +1 more source
Multimodal Image Analysis of Chronic Leukemic Lymphoproliferative Disorders and the Hypothesis of »Single« and »Multiple« Programmed Stops in the Development of Typical and Atypical Forms of Leukemias and Lymphomas [PDF]
, 2010 The study consisted of morphometric analysis, assessment of the argyrophilic nucleolar organization region (AgNOR) characteristics, and image cytometry (ICM) in different tumor mass compartments: bone marrow (BM), peripheral blood (PB) and lymph nodes ...
Biljana Jelić Puškarić +5 more
core +2 more sources
Organoids in Haematologic Research: Advances and Future Directions
Cell Proliferation, EarlyView.This review focuses on the advancements in organoid technology and its transformative role in haematological research, particularly in the modelling of haematopoietic tissues, blood diseases and drug development. It also offers an outlook on the future prospects of organoids in personalised medicine and the study of disease mechanisms.
Liangzheng Chang +4 more
wiley +1 more source
Lymphoma Prevalence Patterns in Uganda, 1969-2006
Middle East Journal of Cancer, 2013 Background: Lymphomas are a complex group of malignancies that requireadvanced technology for proper classification. Unfortunately Uganda, as with numerousother Sub-Saharan African countries, lacks these resources.
Adriane Kamulegeya, Louis Muwazi
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