Results 51 to 60 of about 63,047 (307)

Lymphoblastic T-cell lymphoma in mice is unaffected by Celecoxib as single agent or in combination with cyclophosphamide

, 2009
Celecoxib, an inhibitor of cyclooxygenase-2, is a promising novel antitumor agent with pleitropic mechanisms of action. Whereas this drug induces growth arrest and apoptosis of B-lymphoma cells, its effect against aggressive T-cell neoplasms remains to ...
Lindskog, Magnus,, Holmberg, Dan,, Pawelzik, Sven-Christian, Holmberg, Dan, Johansson, Ann-Sofie,, Jakobsson, Per-Johan, Pawelzik, Sven-Christian,, Jakobsson, Per-Johan,, Johansson, Ann-Sofie, Larefalk, Åsa,, Larefalk, Åsa   +10 more
core   +1 more source

Prenatal origin of childhood AML occurs less frequently than in childhood ALL [PDF]

, 2006
Background While there is enough convincing evidence in childhood acute lymphoblastic leukemia (ALL), the data on the pre-natal origin in childhood acute myeloid leukemia (AML) are less comprehensive.
Meyer, Claus, Schneider, Bjoern, Votava, Felix, Madzo Jozef, Claus Meyer, Jan Trka, Zuna, Jan, Meyer Claus, Marschalek Rolf, Schneider Bjoern, Votava Felix, Tatiana Burjanivova, Burjanivova Tatiana, Zuna Jan, Katerina Muzikova, Muzikova, Katerina, Jan Zuna, Madzo, Jozef, Muzikova Katerina, Burjanivova, Tatiana, Stary Jan, Tatiana Burjanivova, Trka Jan, Marschalek, Rolf (Prof. Dr.), Bjoern Schneider, Rolf Marschalek, Jozef Madzo, Jan Stary, Felix Votava, Trka, Jan, Rolf Marschalek, Stary, Jan   +31 more
core   +1 more source

Enhancing CAR‐T Cell Efficacy in Solid Tumors by Inhibiting CCL5/VEGF‐Mediated Angiogenesis

Advanced Science, EarlyView.
This study reveals that CAR‐T cells in solid tumors produce CCL5, which paradoxically induces VEGF and angiogenesis to promote tumor growth. Blocking CCL5/VEGF signaling—through gene knockout, or the CCR5 inhibitor maraviroc—significantly enhances the antitumor efficacy of CAR‑T therapy (the diagram was created in Biorender).
Shishuo Sun, Qihong Li, Bixi Wang, Gang Wang, Ying Xue, Yibing Liang, Chenhe Hu, Zhenyu Wang, Xiaoge Gao, Haiheng Xu, Jun Song, Hailong Li, Liantao Li, Xiaoxiao Liu, Patrick Ming‐Kuen Tang, Qing Zhang   +15 more
wiley   +1 more source

Late Cytomegalovirus Infections After Allogeneic Hematopoietic Cell Transplant

American Journal of Hematology, EarlyView.
ABSTRACT Graft versus host disease (GVHD) prophylaxis with posttransplant cyclophosphamide (ptCY) and cytomegalovirus (CMV) prophylaxis with letermovir have changed the clinical epidemiology of CMV infection. We studied the incidence, risk factors for, and outcomes of CMV infection after Day + 90 of allogeneic hematopoietic cell transplant (alloHCT ...
George L. Chen, Roland Bassett, Rohtesh S. Mehta, Betul Oran, Fareed Khawaja, Ella J. Ariza‐Heredia, Yosra Aljawai, Amanda Olson, May Daher, Portia Smallbone, Katayoun Rezvani, Partow Kebriaei, Uday Popat, Richard Champlin, Roy F. Chemaly, Elizabeth J. Shpall   +15 more
wiley   +1 more source

Aggressive lung involvement in a patient with T‐acute lymphoblastic leukaemia/lymphoblastic lymphoma: a tricky and rare case report

Respirology Case Reports, 2020
A 39‐year‐old man was admitted to our university hospital because of diffuse pulmonary infiltrates on chest X‐ray. He had been diagnosed with T‐acute lymphoblastic leukaemia/lymphoblastic lymphoma three years before and had been treated with chemotherapy
Chika Miyaoka, Takeshi Saraya, Kojiro Honda, Masachika Fujiwara, Haruyuki Ishii, Hajime Takizawa   +5 more
doaj   +1 more source

Lymphoblastic lymphoma presenting as soft-tissue swelling – A single-center experience

Iraqi Journal of Hematology
BACKGROUND: Lymphoblastic lymphomas (LBL) are a rare, aggressive type of non-Hodgkin lymphomas and constitute 2% of all lymphomas. It is classified as T-lymphoblastic lymphoma (T-LBL) and B lymphoblastic lymphoma (B-LBL) and resembles acute lymphoblastic
Pallavi Nair, Sugeeth M. Thambi, Geetha Narayanan, Jayasudha A. Vasudevan, Ashwin Mohandas Pallath, Sreejith G. Nair   +5 more
doaj   +1 more source

Clonal Hypereosinophilia with ETV6 Rearrangement Evolving to T-Cell Lymphoblastic Lymphoma: A Case Report and Review of the Literature

Case Reports in Hematology, 2013
Hypereosinophilia, either clonal or reactive, has been described in association with multiple hematological malignancies. We describe a case of a patient presenting with hypereosinophilia that evolved into T-cell lymphoblastic lymphoma.
Filipa Moita, Isabel Bogalho, Helena Alaiz, Joana Parreira, Maria Jesus Frade, Albertina Nunes, Maria Gomes da Silva   +6 more
doaj   +1 more source

Transformation of a low-grade follicular lymphoma into a composite lymphoma combining a high-grade B-cell lymphoma and a lymphoblastic neoplasm expressing Terminal deoxynucleotidyl Transferase: a case report

Journal of Medical Case Reports, 2020
Background High-grade B-cell lymphoma with rearrangements of MYC and BCL2 and/or BCL6 is an aggressive mature B-cell neoplasm, whereas B-lymphoblastic lymphoma is immature cell proliferation, with a frequent positivity for terminal deoxynucleotidyl ...
Antonin Bouroumeau, Eleonore Kaphan, Clémentine Legrand, Tatiana Raskovalova, Gautier Szymanski, Claire Vettier, Christine Lefebvre, Marie-Christine Jacob, Anne McLeer, Michel Peuchmaur, Rémy Gressin, Hervé Sartelet   +11 more
doaj   +1 more source

Lineage switch from lymphoma to myeloid neoplasms: First case series from a single institution

Open Medicine, 2022
Lymphoma relapse is very common in clinical work, but lineage switch at relapse is rare. Although some cases have reported acute lymphocytic leukemia (ALL) switch to acute myeloid leukemia (AML) or myeloid sarcoma upon relapse, phenotype switch seldom ...
Yang Wenjuan, Xie Shuangfeng, Li Yiqing, Wang Jieyu, Xiao Jie, Huang Kezhi, Wang Xiuju, Wu Yudan, Ma Liping, Nie Danian   +9 more
doaj   +1 more source

Clinically Relevant Bleeding in Individuals With Cancer: Insights From a Nationwide Cohort Study

American Journal of Hematology, EarlyView.
ABSTRACT Cancer care is often complicated by coagulopathy leading to thrombosis and bleeding. While venous thromboembolism (VTE) has been extensively studied, bleeding remains an underestimated threat. To address this knowledge gap, we leveraged the Epic Cosmos database to determine the impact of cancer‐associated clinically relevant bleeding (CRB) in ...
Ming Y. Lim, Radhika Gangaraju, Omid Jafari, Zihan Yang, Joyce W. T. Tiong, Elizabeth C. L. Chiang, Shengling Ma, Jun Y. Jiang, Justine Ryu, Barbara D. Lam, Mrinal Ranjan, Ang Li   +11 more
wiley   +1 more source