Understanding and Modelling the Complexity of the Immune System: Systems Biology for Integration and Dynamical Reconstruction of Lymphocyte Multi-Scale Dynamics [PDF]
Understanding and modelling the complexity of the immune system is a challenge that is shared by the ImmunoComplexiT$^1$ thematic network from the RNSC. The immune system is a complex biological, adaptive, highly diversified, self-organized and degenerative cognitive network of entities, allowing for a robust and resilient system with emergent ...
arxiv
Myocardial aging as a T-cell–mediated phenomenon [PDF]
In recent years, the myocardium has been rediscovered under the lenses of immunology, and lymphocytes have been implicated in the pathogenesis of cardiomyopathies with different etiologies.
Abeßer, Marco+15 more
core +1 more source
These findings elucidate the innovative role of HIC1 as a transcriptional activator in GC, driving the initiation of pyroptosis and enhancing CD8+ T cell infiltration, which has certain novelty and creative significance. Collectively, targeting HIC1 can present an appealing immunotherapeutic strategy to improve outcomes in GC patients.
Mengjie Kang+4 more
wiley +1 more source
De-Song Shen,1 Chang Yan,1 Yu Liang,1 Kai-Hua Chen,1 Xiao-Dong Zhu1,2 1Department of Radiation Oncology, Guangxi Medical University Cancer Hospital, Nanning, Guangxi, 530021, People’s Republic of China; 2Department of Oncology, Wuming Hospital of Guangxi
Shen DS, Yan C, Liang Y, Chen KH, Zhu XD
doaj
CD4-helper-independent antiviral function of CD8-positive memory T lymphocytes derived from latently infected donors [PDF]
The ability of memory T lymphocytes derived from latently infected mice to control murine cytomegalovirus disease in the immunocompromised host was studied by adoptive transfer experiments.
Jonjic, Stipan+4 more
core +1 more source
Reference Values of Lymphocyte Subsets in Healthy, HIV-Negative Children in Cameroon
Lymphocyte subset reference values used to monitor infectious diseases, including HIV/AIDS, tuberculosis, malaria, or other immunological disorders in healthy children in Cameroon, are lacking.
B. Sagnia+11 more
semanticscholar +1 more source
High Fat Low Carbohydrate Diet Is Linked to CNS Autoimmunity Protection
Mapping global epidemiological data to macronutrient supply reveals high carbohydrate, in contrast to high fat supply, associates with increased multiple sclerosis (MS) prevalence and incidence. This is confirmed in a mouse MS model, experimental autoimmune encephalomyelitis (EAE), using isocaloric diets: a high carbohydrate diet aggravates, a high ...
Duan Ni+15 more
wiley +1 more source
Cancer Detection via Determination of Fractal Cell Dimension [PDF]
We utilize the fractal dimension of the perimeter surface of cell sections as a new observable to characterize cells of different types. We propose that it is possible to distinguish cancerous from healthy cells with the aid of this new approach. As a first application we show that it is possible to perform this distinction between patients with hairy ...
arxiv
Immunogenicity and therapeutic effects of a Mycobacterium tuberculosis rv2190c DNA vaccine in mice [PDF]
The Excel data file [FOLT] Figshare, [DOI: 10.6084/m9.figshare.4668148 and https://figshare.com/s/bd46c22986c673579bb6 ] includes all datasets supporting the conclusions of this article: IFN-Îł in spleen lymphocyte culture supernatants, IL-4 in spleen ...
Jinying Song+9 more
core +2 more sources
Effects of herpes virus carrier status on peripheral T lymphocyte subsets [PDF]
J. W. Gratama+9 more
openalex +3 more sources