Results 201 to 210 of about 1,450,283 (404)

Fragment Autoantigens Stimulated T‐Cell‐Immunotherapy (FAST) as a Fast Autologous Cancer Vaccine

Advanced Science, EarlyView.
A personalized whole tumor cell vaccine (FAST) is developed to address immunosuppressive tumor microenvironments and genomic instability‐driven heterogeneity. Irradiation and cryoablation‐treated tumor cells generate fragmented antigens (FAs) that activate broad‐spectrum antigen presentation via upregulated immunogenic cell death, MHC‐I, and damage ...
Yuan Li, Huiqin Chen, Qiaofeng Shen, Yingshuang Liu, Pingping Li, Yuqi Ma, Yugang Wang, Shengkai Li, Xueqing Yan, Liyu Liu, Jianwei Shuai, Min Wu, Qi Ouyang, Feng‐Ming (Spring) Kong, Gen Yang   +14 more
wiley   +1 more source

New marker of B lymphocytes, MB2: comparison with other lymphocyte subset markers active in conventionally processed tissue sections. [PDF]

, 1987
Peter A. Hall, A J d'Ardenne, Melissa G. Butler, J R Habeshaw, A G Stansfeld   +4 more
openalex   +1 more source

HLA‐DR⁺ Tumor Cells Show an Association with a Distinct Immune Microenvironment and CD8⁺ T‐Cell Exhaustion in HBV‐Associated Hepatocellular Carcinoma

Advanced Science, EarlyView.
This study integrates scRNA‐seq, multiplex immunofluorescence, and clinical data to identify HLA‐DR⁺tumor cells uniquely enriched in Hepatocellular carcinoma (HCC) with hepatitis B virus (HBV). These cells express MHC II, associate with PD‐L1, recruit and exhaust CD8⁺T cells, predict poor survival, and serve as potential biomarkers for immunotherapy ...
Jun‐Qing Chang, Yan Guo, Wen‐Jing Yuan, Yu‐Man Chen, Bo‐Wei Liu, Wen‐Tao Li, Xiang‐Ming Ding, Xu‐Dong Fu, Yu‐Han Lou, Zhuo‐Ran Chen, Xiao‐Ying Luo, Song‐Ze Ding, Bing‐Yong Zhang, Xiu‐Ling Li, Yong‐Zhi Hong, Shun‐Dong Cang, Dong‐Xiao Li, Ling Lan   +17 more
wiley   +1 more source

Changes and Clinical Significance of Detailed Peripheral Lymphocyte Subsets in Evaluating the Immunity for Cancer Patients

Cancer Management and Research, 2020
Jinrong Qiu, 1,* Fuping Zhou, 1,* Xinchun Li, 2,* Sufang Zhang, 2 Zhuo Chen, 2 Zenghui Xu, 2 Gaoxiong Lu, 2 Zhi Zhu, 3 Na Ding, 2 Jinxing Lou, 4 Zhenlong Ye, 2 Qijun Qian 1, 2, 4  1Department of Biotherapy, Eastern Hepatobiliary Surgery Hospital ...
Qiu J, Zhou F, Li X, Zhang S, Chen Z, Xu Z, Lu G, Zhu Z, Ding N, Lou J, Ye Z, Qian Q   +11 more
doaj  

Immunocto: a massive immune cell database auto-generated for histopathology [PDF]

arXiv
With the advent of novel cancer treatment options such as immunotherapy, studying the tumour immune micro-environment (TIME) is crucial to inform on prognosis and understand potential response to therapeutic agents. A key approach to characterising the TIME may be through combining (1) digitised microscopic high-resolution optical images of hematoxylin
arxiv  

Expression of T-cell-activating protein in peripheral lymphocyte subsets.

, 1986
E T Yeh, Hans Reiser, Beryl R. Benacerraf, Kenneth L. Rock   +3 more
openalex   +1 more source

Thyroid-Infiltrating T Lymphocyte Subsets in Hashimoto's Thyroiditis* [PDF]

, 1983
Rolf Jansson, Thomas H. Tötterman, Jan Sällström, Per Anders Dahlberg   +3 more
openalex   +1 more source

Nucleic Acid‐Locked Smart Carrier for Photothermal/Chemotherapy‐Amplified Immunogenic Cell Death to Enhance Systemic Antitumor Efficacy

Advanced Science, EarlyView.
Multiple therapeutic modalities combined in a synergistic way that can modulate different immune axes are demonstrated potentially effective in boosting immunotherapy. A nucleic acid‐locked smart carrier (NASC) performed as an “all‐in‐one” nanoplatform is constructed for efficient eliciting chemo‐ and photothermal‐amplified immunogenic cell death to ...
Jiayang Zhang, Tianyu Gai, Jiwei Wang, Yucai Wu, Si‐Ming Zeng, Dongyuan Zhao, Wei Li   +6 more
wiley   +1 more source

Predictive value of lymphocyte subsets and lymphocyte-to-monocyte ratio in assessing the efficacy of neoadjuvant therapy in breast cancer

Scientific Reports
Lymphocyte subsets are the most intuitive expression of the body’s immune ability, and the lymphocyte-to-monocyte ratio (LMR) also clearly reflect the degree of chronic inflammation activity.
Hao Zhang, Yan Li, Ya-Wen Liu, Ye-Gang Liu, Xin Chen   +4 more
doaj   +1 more source

Blood Biomarker‐Based Predictive Indicator for Liver Metastasis in Alpha‐Fetoprotein‐Producing Gastric Cancer and Multi‐Omics Tumor Microenvironment Insights

Advanced Science, EarlyView.
Alpha‐fetoprotein‐producing gastric cancer (AFPGC), a rare and aggressive subtype of gastric cancer, presents a high risk of liver metastasis. This study introduces the ANLiM score, a blood biomarker‐based predictive indicator for assessing liver metastasis and immunotherapy response.
Yongfeng Ding, Yiran Chen, Jing Zhang, Qingrui Wang, Songting Zhu, Junjie Jiang, Chao He, Jincheng Wang, Laizhen Tou, Jingwei Zheng, Bicheng Chen, Sizhe Hu, Xiongfei Yu, Haohao Wang, Yimin Lu, Mei Kong, Yanyan Chen, Haiyong Wang, Haibin Zhang, Hongxia Xu, Fei Teng, Xian Shen, Nong Xu, Jian Ruan, Zhan Zhou, Jun Lu, Lisong Teng   +26 more
wiley   +1 more source