Results 41 to 50 of about 88,304 (257)

Use of the Monocyte-to-Lymphocyte Ratio to Predict Diabetic Retinopathy [PDF]

International Journal of Environmental Research and Public Health, 2015
Background: Diabetic retinopathy (DR) is a common complication of type 2 diabetes mellitus (T2DM) and the leading cause of blindness in adults. DR pathogenesis has not been fully elucidated, but inflammation is widely accepted to play an important role. Emerging evidence suggests that the platelet-to-lymphocyte ratio (PLR), monocyte-to-lymphocyte ratio
Yue, Song, Zhang, Jiahua, Wu, Jingyang, Teng, Weiping, Liu, Lei, Chen, Lei   +5 more
openaire   +2 more sources

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Prognostic value of pretreatment inflammatory biomarkers in patients with laryngeal cancer

Asian Journal of Surgery
Summary: Objectives: The systemic inflammatory response is strongly involved in the progression of malignant tumors, and it is useful for predicting survival time and determining therapeutic effects. The inflammatory biomarkers, neutrophil-to-lymphocyte
Toshiaki Kawano, Takashi Hirano, Kaori Tateyama, Kazuhiro Yoshinaga, Kaori Shinomura, Masashi Suzuki   +5 more
doaj   +1 more source

The neutrophil-to-lymphocyte and monocyte-to-lymphocyte ratios are independently associated with clinical outcomes of viral encephalitis

Frontiers in Neurology, 2023
BackgroundThe neutrophil-to-lymphocyte ratio (NLR) and monocyte-to-lymphocyte ratio (MLR) are used as prognostic biomarkers for many diseases. In this study, we aimed to explore the possibility of using ratios of NLR and MLR to predict the prognosis of ...
Qiang He, Qiang He, Qiang He, Shuo Wang, Haoan Chen, Lili Long, Lili Long, Lili Long, Bo Xiao, Bo Xiao, Bo Xiao, Kai Hu, Kai Hu, Kai Hu   +13 more
doaj   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy

Molecular Oncology, EarlyView.
LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir, Elena Haro‐Martínez, Sandra Blasco‐Benito, Chiara Cannatà, José Ángel Palomeque, Anna López‐Plana, Maria Sanz‐Flores, Marc Sabartés, Cristina Fornaguera, Toni Celià‐Terrassa   +9 more
wiley   +1 more source

Which inflammatory marker might be the best indicator for sacroiliitis?

Precision Medical Sciences, 2023
This study aimed to investigate the potential of inflammatory markers, including platelet‐to‐lymphocyte ratio (PLR), neutrophil‐to‐lymphocyte ratio (NLR), lymphocyte‐to‐monocyte ratio (LMR), and C‐reactive protein‐to‐lymphocyte ratio (CLR), in ...
Melike Elif Kalfaoglu, Zeliha Cosgun
doaj   +1 more source

Influenza Vaccination Responses in Disabled Stroke Patients: A Single‐Center Prospective Observational Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study aimed to investigate the immunological response to influenza vaccination, the incidence and severity of influenza infection, and the side effects of the vaccination in patients with ischemic stroke. Methods This prospective observational study was conducted between 2023 and 2024 at Ramathibodi Hospital.
Achiraya Pakngao, Sureerat Suwatcharangoon, Pintip Ngamjanyapron, Kobporn Boonnak, Thanitta Suangtamai, Porpon Rotjanapan   +5 more
wiley   +1 more source

Peripheral Immune Cell Ratios and Clinical Outcomes in Seropositive Autoimmune Encephalitis: A Study by the Australian Autoimmune Encephalitis Consortium

Frontiers in Immunology, 2021
ObjectiveTo examine the utility of the peripheral blood neutrophil-to-lymphocyte ratio (NLR) and monocyte-to-lymphocyte ratio (MLR) as biomarkers of prognosis in seropositive autoimmune encephalitis (AE).MethodsIn this multicenter study, we ...
James Broadley, James Broadley, Robb Wesselingh, Robb Wesselingh, Udaya Seneviratne, Udaya Seneviratne, Udaya Seneviratne, Chris Kyndt, Chris Kyndt, Paul Beech, Paul Beech, Katherine Buzzard, Katherine Buzzard, Cassie Nesbitt, Cassie Nesbitt, Wendyl D’Souza, Wendyl D’Souza, Amy Brodtmann, Amy Brodtmann, Tomas Kalincik, Tomas Kalincik, Helmut Butzkueven, Helmut Butzkueven, Terence J. O’Brien, Terence J. O’Brien, Mastura Monif, Mastura Monif, Mastura Monif, Mastura Monif, Australian Autoimmune Encephalitis Consortium   +29 more
doaj   +1 more source

Analysis of Monocyte/Lymphocyte Ratio and Monocyte/HDL Ratio as A Predictor of Mortality in ACS

INDONESIAN JOURNAL OF CLINICAL PATHOLOGY AND MEDICAL LABORATORY, 2023
Inflammatory process plays a role in the prognosis and development of Acute Coronary Syndrome (ACS). Inflammation parameters associated with ACS mortality are Monocyte/Lymphocyte ratio (MLR) and Monocyte/High Density Lipoprotein ratio (MHR). This study aimed to analyze MLR and MHR as predictors of ACS mortality based on the GRACE score.
Nanda Amelia, Tenri Esa
openaire   +1 more source