Results 171 to 180 of about 745,482 (386)

CDK4/6 Inhibition Induces CD8+ T Cell Antitumor Immunity via MIF‐Induced Functional Orchestration of Tumor‐Associated Macrophages

Advanced Science, EarlyView.
CDK4/6 inhibition promotes CD8+ T cell expansion through tumor‐macrophage crosstalk by activating HIF‐1α and enhancing MIF‐CD44/CD74 signaling. This reprograms TAMs to boost MHC‐I antigen presentation, and CDK4/6 inhibitor‐trained M1 TAM supernatant therapy synergizes with low‐dose PD‐1 blockade to restore antitumor immunity.
Lin He, Yuzhong Peng, Lat‐lun Leong, Jingbo Zhou, Dongyang Tang, Weilu Wang, Xiaoran Wu, Josh haipeng Lei, Yongqin Ye, Yangyang Feng, Yunfeng Qiao, Xiangpeng Chu, Di Mu, Qi Zhao, Tzuming Liu, Yan Chen, Paul Kwonghang Tam, Chu‐Xia Deng   +17 more
wiley   +1 more source

Red Blood Cells Internalize Extracellular DNA via Apoptotic Bodies with Clinical Relevance to Cancer Patients

Advanced Science, EarlyView.
Mature red blood cells (RBCs) can capture extracellular DNA, with short fragments homologous to cfDNA. This uptake is mediated by apoptotic bodies, which induce RBC oxidative stress, deformation, and accelerated in vivo clearance. The rbcDNA abundance correlates with tumor burden and therapeutic response, highlighting its potential as a liquid biopsy ...
Zihang Zeng, Zongbi Yi, Jing Hu, Jiali Li, Yu Xu, Xiuli Guo, Qian Ji, Kaixiang Feng, Ying Zhang, Sirui Bai, Yushuang Tan, Yufei Yan, Linzhi Han, Jing Jiang, Tengfei Wang, Xiang Wang, Ziqing Zhan, Ruiying Huang, Jinfang Zhang, Conghua Xie, Binghe Xu   +20 more
wiley   +1 more source

Dysregulated Lymphoid Cell Populations in Mouse Models of Systemic Lupus Erythematosus

, 2017
Aurélie De Groof, Patrice Hémon, Olivier Mignen, Jacques‐Olivier Pers, Edward K. Wakeland, Yves Renaudineau, Bernard Lauwerys   +6 more
openalex   +2 more sources

Function of Innate Lymphoid Cells in Periodontal Tissue Homeostasis: A Narrative Review [PDF]

, 2023
Zhiyu Ma, Jinsong Wang, Lei Hu, Songlin Wang   +3 more
openalex   +1 more source

A revised European-American classification of lymphoid neoplasms: a proposal from the International Lymphoma Study Group.

Blood, 1994
N. Harris
semanticscholar   +1 more source

Aberrant SUMOylation Restricts the Targetable Cancer Immunopeptidome

Advanced Science, EarlyView.
Pharmacological SUMOylation inhibition (SUMOi) counteracts tumor immune evasion by unmasking an immunogenic HLA‐I peptide and neoepitope repertoire. By restoring HLA‐I ligand availability through increased antigen processing and presentation, enhanced proteasomal cleavage, and modulated TAP1 peptide affinity, SUMOi boosts tumor immunogenicity ...
Uta M. Demel, Anna Meurer, Badeel Kh. Q. Zaghla, Bilge Atay, Daniel Steiert, Luca V. Hummel, Konstandina Isaakidis, Chuanbing Zang, Michael Korenkov, Marlon Schielin, Schayan Yousefian, Shima Mecklenbräuker, Marieluise Kirchner, Simon Haas, Antonia Busse, Philipp Mertins, Stefan Müller, Matthias Wirth, Martin G. Klatt, Ulrich Keller   +19 more
wiley   +1 more source

P094: Long-term outcomes of bulky classic Hodgkin lymphoma managed with a PET-adapted approach demonstrate excellent outcomes in PET-negative cases

HemaSphere, 2022
Jowon Laura Kim, Diego Villa, R. Petter Tonseth, Alina S. Gerrie, Don Wilson, Francois Benard, Chris Venner, Brian Skinnider, Pedro Farinha, Graham W. Slack, David W. Scott, Joseph M. Connors, Laurie H. Sehn, Kerry J. Savage   +13 more
doaj   +1 more source

Helicobacter pylori (H. pylori) molecular signature in conjunctival mucosa-associated lymphoid tissue (MALT) lymphoma.

, 2004
C-C Chan, James A. Smith, Defen Shen, Roxana Ursea, Phuc LeHoang, Hans E. Grossniklaus   +5 more
openalex   +2 more sources

Lymphoid Goitres [PDF]

Postgraduate Medical Journal, 1957
openaire   +2 more sources

Tertiary lymphoid structures in the era of cancer immunotherapy

Nature Reviews. Cancer, 2019
C. Sautès-Fridman, F. Petitprez, J. Calderaro, W. Fridman   +3 more
semanticscholar   +1 more source