Results 121 to 130 of about 258,275 (268)

Optimizing Cancer Vaccinations Using a Physiologically‐Based Pharmacokinetic/Pharmacodynamic (PBPK/PD) Model

Advanced Science, EarlyView.
Where and when should a cancer vaccine be administered? A whole‐body PBPK model demonstrates that systemic immune transport critically determines vaccination efficacy. By simulating how organ‐specific immune interactions influence treatment response, the study provides a quantitative framework for optimizing cancer vaccination strategies.
Mohammad R. Nikmaneshi, Timothy P. Padera, Lance L. Munn   +2 more
wiley   +1 more source

Lymphoid-Tissue-on-Chip Recapitulates Human Antibody Responses In Vitro. [PDF]

Adv Sci (Weinh)
Teufel C, Schlemmer AS, Eiken AW, Wagoner ZW, Vöhringer D, Christ L, Dulovic A, Marsall P, Fandrich M, Brás EJS, Marzi J, Bärhold F, Philipp J, Becker S, Wagar LE, Loskill P.   +15 more
europepmc   +1 more source

Decoding Biomolecular Phase Separation: From Physiological Roles to Pathological Mechanisms and Therapeutic Biomaterials Design

Advanced Science, EarlyView.
This review systematically elaborates on the mechanisms underlying physiological regulation and pathological dysregulation of biomolecular phase separation. It also summarizes advances in phase‑separation‑targeted therapeutic strategies and the design of functional biomaterials inspired by this process.
Jiawei Zhu, Jingbo Dong, Qiufang Gong, Xuejiao Song, Zhifa Shen, Chao Liang   +5 more
wiley   +1 more source

Gallbladder Mucosa-Associated Lymphoid Tissue (MALT) Lymphoma With Gallstone Pancreatitis and Prostate Cancer. [PDF]

Cureus
Kim Y, Vaishampayan N, Boggula R, Hart KB, Gabali A, Saad A, Miller SR.   +6 more
europepmc   +1 more source

Sonogenetic Control of Engineered Probiotics for the Treatment of MASH by Modulating the Gut‐Liver Axis

Advanced Science, EarlyView.
Researchers developed an engineered probiotic encapsulated in an inulin hydrogel, enabling ultrasound‐triggered intestinal delivery of IL‐22. In MASH model mice, this system remodeled gut microbiota, strengthened the intestinal barrier and reduced portal LPS and hepatic IL‐6.
Chunya Ji, Yan Fang, Shen Zhang, Weichen Xu, Wenyun Guo, Jing Chen, Mingrui Zhu, Congjian Wen, Siming Chen, Yuli Zhu, Huixiong Xu, Haohao Yin   +11 more
wiley   +1 more source

Synchronous mucosa-associated lymphoid tissue lymphoma in a married couple: a case report. [PDF]

Front Oncol
Cheng M, Pi Y, Ren K, Li W, Zou L.
europepmc   +1 more source

Lactate Signal: Modulator of Cellular Energy Production and Anabolism

Advanced Science, EarlyView.
Compartmentalized lactate signaling provides a spatial framework for understanding how lactate‐rich states are generated, transported, sensed, and translated into biological outputs. This Review integrates extracellular, cytosolic, mitochondrial‐associated, and nuclear lactate mechanisms to explain how lactate shapes metabolic adaptation, immune ...
Han Wang, Si‐Yuan Yang, Wei Xu
wiley   +1 more source

The Omentum as a Lymphoid Tissue: Its Molecular Aspects and Application in a Murine Model. [PDF]

Arch Plast Surg
Hojo M, Seo D, Ito R, Ishikawa K, Miura T, Funayama E, Yamamoto Y, Maeda T.   +7 more
europepmc   +1 more source

Lymphoid Tissue of the Alimentary Canal [PDF]

BMJ, 1938
openaire   +2 more sources

Immune Biomarkers of Islet Transplant Rejection Revealed by Synthetic Immunological Niche

Advanced Science, EarlyView.
A subcutaneous synthetic immunological niche (IN) enables serial, minimally invasive monitoring of immune responses after islet transplantation. Flow cytometry and transcriptomic profiling of the IN reveal immune‐cell programs associated with graft acceptance and distinct types of rejection.
Jyotirmoy Roy, Abdalmonam Jadou Nejma, Mohammad Tarique, Amod Talekar, Shengli Wu, Brianna Ha, Yifei Jiang, Esma S. Yolcu, Lonnie D. Shea   +8 more
wiley   +1 more source