Results 171 to 180 of about 17,698,083 (199)
Abstract CD19‐directed CAR‐T cell therapy has become the standard of care for the treatment of relapsed/refractory LBCL, MCL, FL and BCP‐ALL. Expansion of CAR‐T cells in the peripheral blood (PB) of patients in the first weeks after infusion is an important biomarker for the prediction of therapy response and occurrence of toxicities.
Gerulf Hänel +16 more
wiley +1 more source
Comparison of EBER flow FISH results from two facilities
Abstract Epstein–Barr virus (EBV) primarily infects B cells but can occasionally target T and/or NK cells, leading to chronic active EBV disease or EBV‐associated hemophagocytic lymphohistiocytosis, which are often difficult to treat. EBV‐associated diseases exhibit a wide range of phenotypes.
Madoka Nishimura +13 more
wiley +1 more source
ABSTRACT Fine‐needle aspiration cytology specimens are frequently utilized for ancillary studies to identify diagnostic and prognostic information. This case highlights diagnostic pitfalls and challenges in diagnosing NUTM1‐rearranged neoplasia on pancreatic cytology.
Terrance J. Lynn
wiley +1 more source
Leptomeningeal Carcinomatosis: A Diagnosis Challenge
ABSTRACT Background Leptomeningeal carcinomatosis (LC) in patients with disseminated cancer has a grave prognosis and limited therapeutic options. Diagnosis is delayed due to low CSF volume and scant cellularity. This quality improvement project was undertaken to evaluate the diagnostic performance of CSF cytology in cases with radiologic evidence and ...
Makayla Hyde +3 more
wiley +1 more source
Abstract Aims Immune checkpoint inhibitors (ICI) are the cornerstone of modern oncology; however, side effects such as ICI‐related myocarditis (irM) can be fatal. Recently, Bonaca proposed criteria for irM; however, it is unknown if they correlate well with cardiovascular (CV) ICI‐related adverse events.
Lorenzo Braghieri +12 more
wiley +1 more source
This study analyzes 148 patients (66 women and 82 men) with chronic myeloid leukemia treated with tyrosine kinase inhibitors, focusing on cardiovascular adverse events. The risk assessment, performed using the HFA/ICOS score, reveals sex‐specific differences: venous thrombosis is more common in women, while arterial thrombosis predominates in men.
Cristina Madaudo +10 more
wiley +1 more source
ABSTRACT Introduction Thyroid nodules are less common but more often malignant in pediatric patients than in adults. Our objectives were to study the features of benign vs. malignant thyroid nodules in a large pediatric patient cohort. Methods Retrospective observational cohort study. Consecutive patients aged 0.01–17.9 years at evaluation between 1997–
Maxime Gest‐Laurent +15 more
wiley +1 more source
A case report: Diagnosis and treatment of idiopathic hypertrophic pachymeningitis
We reported a case of idiopathic hypertrophic dura meningitis diagnosed in our hospital. The patient repeatedly suffered from headaches, followed by blurred vision in the right eye. During this period, multiple sclerosis was considered for diagnosis, and it improved after hormone treatment.
Zhong Luo +7 more
wiley +1 more source
Activity of Low Dose Nivolumab in Patients With Advanced Squamous Cell Carcinomas and Other Cancers
ABSTRACT Immune checkpoint inhibitors such as anti–PD‐1 antibodies are essential in cancer therapy. Emerging data suggest that lower doses may be effective and more economical, though further evidence is needed. We conducted a retrospective study at Centre Léon Bérard to assess the efficacy and safety of low‐dose nivolumab (20 mg every 3 weeks) in ...
Thibault Gauduchon +16 more
wiley +1 more source
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