Results 101 to 110 of about 596,620 (345)

Sjögren Disease—B Cells at the Brink: From Autoimmunity to Lymphomagenesis and the Rise of Novel B Cell–Targeted Therapies

Arthritis &Rheumatology, EarlyView.
Sjögren disease (SjD) is a common systemic autoimmune disorder characterized by inflammation of the exocrine glands, resulting in dryness. Patients frequently exhibit extraglandular manifestations affecting various organ systems. To date, there are no US Food and Drug Administration (FDA)‐approved disease‐modifying therapies for SjD. In this review, we
Rachael A. Gordon, Sara S. McCoy
wiley   +1 more source

Follicular T-cell lymphoma: A rare entity

Hematology Reports, 2020
Follicular T-cell lymphoma: A rare entity Background: Follicular T-cell lymphoma (FTCL) is a recently described variant of peripheral T-cell lymphoma, NOS in the World Health Organization (WHO) classifications of lymphoid neoplasms. It is a rare neoplasm
O.T. Eryilmaz, N. Dogruyol, A. Ozagari, F. Kabukcuoglu   +3 more
doaj  

Prognostic Assessment in Patients with Indolent B-Cell Lymphomas

The Scientific World Journal, 2012
Follicular lymphoma (FL) is an indolent lymphoma with long median survival. Many studies have been performed to build up prognostic scores potentially useful to identify patients with poorer outcome.
Luca Arcaini, Sara Rattotti, Manuel Gotti, Stefano Luminari   +3 more
doaj   +1 more source

Integrated Clinical and Proteomic Profiling of CD19 CAR‐T Cell Therapy in Progressive Systemic Sclerosis

Arthritis &Rheumatology, Accepted Article.
Objective To characterize the clinical, immunologic, and proteomic changes associated with CD19 chimeric antigen receptor T‐cell therapy in patients with progressive systemic sclerosis. Methods Patients with progressive systemic sclerosis received CD19 CAR‐T cell therapy and were followed longitudinally for safety, clinical efficacy, immune ...
Chenhan Jia, Wanyi Lin, Zhangyi Zhao, Fenglin Wu, Chaoyu Gu, Yuankai Sun, Zhe Ding, Chang Wei, Xinyu Li, Cuiwei Xie, Peng Xia, Zhen Xia, Xuesong Liu, Shaoying Yang, Chunyan Zhang, Hanlin Yin, Liangjing Lu   +16 more
wiley   +1 more source

Integrative clinicopathological and molecular analyses of angioimmunoblastic T-cell lymphoma and other nodal lymphomas of follicular helper T-cell origin

Haematologica, 2017
In addition to angioimmunoblastic T-cell lymphoma (AITL), the 2016 revised WHO classification of haematological malignancies recognizes two provisional lymphoma entities of follicular helper T-cell (TFH) derivation, namely follicular peripheral T-cell ...
M. P. Dobay, F. Lemonnier, E. Missiaglia, C. Bastard, D. Vallois, J. Jais, L. Scourzic, A. Dupuy, V. Fataccioli, A. Pujals, M. Parrens, Fabien Le Bras, T. Rousset, J. Picquenot, N. Martin, C. Haioun, R. Delarue, O. Bernard, M. Delorenzi, L. de Leval, P. Gaulard   +20 more
semanticscholar   +1 more source

Pathogenesis of follicular lymphoma [PDF]

Best Practice & Research Clinical Haematology, 2018
Follicular lymphoma (FL) is presented as a germinal centre B cell lymphoma that is characterized by an indolent clinical course, but remains - paradoxically - largely incurable to date. The last years have seen significant progress in our understanding of FL lymphomagenesis, which is a multi-step process beginning in the bone marrow with the hallmark t(
Tracy Lackraj, Rashmi Goswami, Robert Kridel   +2 more
openaire   +2 more sources

Homocitrullinated Peptides Drive Pro‐Inflammatory T‐Cell Responses in a Humanized Mouse Model of Rheumatoid Arthritis

Arthritis &Rheumatology, Accepted Article.
Objective Anti‐homocitrullinated protein/peptide antibodies are specific to rheumatoid arthritis (RA) and predictive of worse prognosis, suggesting a pathogenic role for autoreactivity to homocitrullinated peptides (HomoCitP). However, T‐cell responses to HomoCitP remain largely unexplored.
Sofya Ulanova, Jaspreet Kaur, Gabrielle Buckley, S.M. Mansour Haeryfar, Lisa Cameron, Ewa Cairns, Lillian Barra   +6 more
wiley   +1 more source

Plasmablastic transformation of a double hit follicular lymphoma: An emerging entity

Indian Journal of Pathology and Microbiology
Plasmablastic transformation of follicular lymphoma is very rare and has been reported in only 5 cases till date. We report a case of simultaneous identification of extranodal, soft tissue plasmablastic lymphoma in the ankle and bone marrow involvement ...
Shanaz Khodaiji, Vidisha Mahajan, Krishna Sawaimoon Satyakam, Pratibha Sudhan Kadam Amare   +3 more
doaj   +1 more source

Controversies in the Treatment of Follicular Lymphoma

HemaSphere, 2020
. The overall prognosis of patients with follicular lymphoma has substantially improved over the last decades with a 10-year overall survival of around 80% for the majority of patients.
Kai Hübel, Michele Ghielmini, Marco Ladetto, Ajay K. Gopal   +3 more
doaj   +1 more source

CD4 T lymphocyte autophagy is upregulated in the salivary glands of primary Sjögren’s syndrome patients and correlates with focus score and disease activity [PDF]

, 2017
Background: Primary Sjögren’s syndrome (pSS) is a common chronic autoimmune disease characterized by lymphocytic infiltration of exocrine glands and peripheral lymphocyte perturbation.
A Bhattacharya, AG Tzioufas, Annacarla Finucci, Antonina Minniti, Aroldo Rizzo, C Alessandri, C Li, C Vitali, C Vitali, CQ Nguyen, Cristiana Barbati, Cristiano Alessandri, D Geem, DJ Klionsky, DM Chisholm, E Astorri, Elena Ortona, Elisa Astorri, F Barone, F Ciccia, F Ciccia, F Ciccia, F Ciccia, F Sallusto, Fabrizio Conti, Francesco Ciccia, Giovanni Triolo, Giuliana Guggino, Guido Valesini, H Nakatogawa, HH Pua, HH Pua, HH Pua, I Tanida, LM Gerland, M Bombardieri, M Bombardieri, M Morgan-Bathke, M Morgan-Bathke, M Moriyama, M Pierdominici, Marina Pierdominici, Marta Vomero, Monica Pendolino, N Mizushima, N Schmitt, R Seror, Riccardo Alessandro, Roberta Priori, S Katsiougiannis, S Romao, Tania Colasanti, TC Adamson 3rd, W Jia, Walter Malorni, XJ Zhou, Y Seo, YZ Gong, Z Yang   +58 more
core   +3 more sources