Results 201 to 210 of about 244,635 (318)

Precision Oncology for Pediatric Solid Tumors Using In‐Hospital Pediatric/AYA Malignancy‐Specific Panel Sequencing

open access: yesCancer Science, EarlyView.
Our findings indicate that a pediatric/AYA‐specific targeted panel deployed in a hospital can deliver rapid, clinically actionable molecular insights with high diagnostic and prognostic yield. This complements larger sequencing platforms by offering speed, focused content, and easier interpretation.
Masato Kojima   +8 more
wiley   +1 more source

Combinatorial targeting of MYC/BCL2‐associated vulnerabilities in high‐grade B‐cell lymphoma

open access: yes
British Journal of Haematology, EarlyView.
Giulio Donati   +6 more
wiley   +1 more source

Recent trends of incidence and mortality of cutaneous lymphomas in Germany

open access: yesJDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary Background Primary cutaneous lymphomas (PCL) are primarily composed of cutaneous T‐cell lymphomas (CTCL), followed by cutaneous B‐cell lymphomas (CBCL). This study aimed to assess the incidence and survival rates of PCL in Germany. Methods We analyzed data from the North Rhine‐Westphalia Cancer Registry (2008–2021), which covers a population of
Khodr Cheikh El Najjarine   +4 more
wiley   +1 more source

Validation of prognostic scores in patients with HIV‐related diffuse large B‐cell lymphoma: The value of peripheral blood parameters—A study from the Spanish Lymphoma Group GELTAMO

open access: yes
British Journal of Haematology, EarlyView.
Maria Huguet   +19 more
wiley   +1 more source

The Role of SAMHD1 in Viral Resistance and Transduction Efficiency Challenges in Pediatric Hematological Malignancies: Mechanistic Insights and Clinical Perspectives

open access: yesEuropean Journal of Haematology, EarlyView.
SAMHD1 regulates intracellular dNTP pools, influencing lentiviral transduction, gene therapy efficiency, and disease progression in pediatric hematological malignancies. Integrated bioinformatics and targeted strategies, including CRISPR and pharmacological inhibition, highlight its therapeutic potential.
Waseem Alzamzami
wiley   +1 more source

Microbiome‐Based Modeling of CAR‐T Therapy Response in Lymphoma: Insights From Shotgun Metagenomics Sequencing

open access: yesEuropean Journal of Haematology, EarlyView.
ABSTRACT The interplay between the commensal microbiota and the mammalian immune system may influence the outcomes of T cell‐driven cancer immunotherapies. However, clinical studies supporting microbiota‐based interventions in chimeric antigen receptor T‐cell (CAR‐T) therapy remain scarce.
Rafael Hernani   +22 more
wiley   +1 more source

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