Results 91 to 100 of about 138,230 (307)

A bioinformatic analysis identifies circadian expression of splicing factors and time-dependent alternative splicing events in the HD-MY-Z cell line [PDF]

, 2019
The circadian clock regulates key cellular processes and its dysregulation is associated to several pathologies including cancer. Although the transcriptional regulation of gene expression by the clock machinery is well described, the role of the clock ...
Abreu, Mónica, Astaburuaga, Rosario, Basti, Alireza, Genov, Nikolai, Relógio, Angela   +4 more
core   +1 more source

Diagnosing Non-Hodgkin's Lymphoma [PDF]

Laboratory Medicine, 2007
Non-Hodgkin’s lymphomas (NHLs) are lymphoid malignancies representing the sixth most common type of cancer diagnosed in men and women in the United States. Between 1973 and 2000, incidence rates for NHL in the United States increased nearly 80%, one of the largest increases observed among all cancers. 1 An increased risk of disease has been found among
openaire   +1 more source

Non-Hodgkin Lymphoma Metabolism

, 2021
AbstractNon-Hodgkin lymphomas (NHLs) are a heterogeneous group of lymphoid neoplasms with different biological characteristics. About 90% of all lymphomas in the United States originate from B lymphocytes, while the remaining originate from T cells [1].
Brian James, Kirsch, Shu-Jyuan, Chang, Michael James, Betenbaugh, Anne, Le   +3 more
openaire   +2 more sources

Single‐Cell Level Characterization of B Cell Depletion and Repopulation Following Rituximab in Systemic Lupus Erythematosus

Arthritis &Rheumatology, EarlyView.
Objective Rituximab, a CD20+ B cell depletion therapy, is frequently used to treat systemic lupus erythematosus (SLE). However, variability in patient response highlights the need for a deeper understanding of the underlying immune cell dynamics of B cell depletion and repopulation.
Haerin Jang, Norzawani Buang, Catherine Sutherland, Wanseon Lee, Lauren Overend, Tarran S. Rupall, Katie L. Burnham, Matthew C. Pickering, Marina Botto, Emma E. Davenport   +9 more
wiley   +1 more source

Acromial Osteotomy for Dynamic Posterior Shoulder Instability

Arthroscopy Techniques, EarlyView.
Abstract Posterior shoulder instability is less prevalent than anterior instability but shows a rising incidence, particularly among young and active individuals. Diagnosis is often challenging due to nonspecific symptoms, leading to delays and underestimation of prevalence. Its etiology is multifactorial, including traumatic events, iatrogenic causes,
Ricardo Mendes, José Carlos Garcia Jr, Matheus Barcelos, Airthon Correia, Lucas Fiori, Mauricio Raffaelli, Marcelo Mello   +6 more
wiley   +1 more source

Laryngeal lymphoma : the high and low grades of rare lymphoma involvement sites [PDF]

, 2014
The larynx is an extremely rare site of involvement by lymphomatous disease.We present two cases of isolated laryngeal high-grade and another low-grade lymphoma, together with a literature review of laryngeal lymphoma management.peer ...
Azzopardi, Charles Paul, Betts, Alexandra, Camilleri, David J., Degaetano, James, Farrugia, Eric, Gatt, Alexander, Magri, Claude, Refalo, Nicholas   +7 more
core   +3 more sources

Non-Hodgkin’s Lymphomas [PDF]

Journal of the National Comprehensive Cancer Network, 2010
Andrew D, Zelenetz, Jeremy S, Abramson, Ranjana H, Advani, C Babis, Andreadis, Nancy, Bartlett, Naresh, Bellam, John C, Byrd, Myron S, Czuczman, Luis E, Fayad, Martha J, Glenn, Jon P, Gockerman, Leo I, Gordon, Nancy Lee, Harris, Richard T, Hoppe, Steven M, Horwitz, Christopher R, Kelsey, Youn H, Kim, Ann S, LaCasce, Auayporn, Nademanee, Pierluigi, Porcu, Oliver, Press, Barbara, Pro, Nashitha, Reddy, Lubomir, Sokol, Lode J, Swinnen, Christina, Tsien, Julie M, Vose, William G, Wierda, Joachim, Yahalom, Nadeem, Zafar   +29 more
openaire   +3 more sources

Effect of developmental changes on pharmacokinetics of drugs used in the treatment of infant acute lymphoblastic leukaemia—A comprehensive review

British Journal of Clinical Pharmacology, EarlyView.
While the event‐free survival (EFS) of children treated for acute lymphoblastic leukaemia (ALL) has improved greatly in the last decades, the EFS for patients diagnosed with ALL before the age of one is still under 50%. This outcome further decreases when infants have a rearrangement in the gene encoding histone‐lysine N‐methyltransferase 2A (KMT2A ...
Tirsa de Kluis, Leiah J. Brigitha, Lidwien M. Hanff, Alwin D. R. Huitema, Inge M. van der Sluis, Meta H. M. Diekstra   +5 more
wiley   +1 more source

Concomitant Choroidal Melanoma and Non-Hodgkin Lymphoma in Two Adult Patients: Case Report

Case Reports in Ophthalmology, 2012
Objective: To report two cases of concomitant choroidal melanoma and intraocular non-Hodgkin lymphoma in two patients. Design: Case report. Participants: Two patients with yellow creamy infiltrates in fundo.
Marcel Vlaskamp, Didi de Wolff-Rouendaal, Patty M. Jansen, Gre P.M. Luyten   +3 more
doaj   +1 more source

Population pharmacokinetics and dose–response relationships of mitoxantrone in children with acute myeloid leukaemia

British Journal of Clinical Pharmacology, EarlyView.
Background Information on mitoxantrone pharmacokinetics in children is lacking and reduced dosing regimens applied to infants are supported by limited scientific rationale. The current study characterized mitoxantrone pharmacokinetics in a childhood acute myeloid leukaemia patient population and provides a data‐informed assessment of dosing.
Andrew M. Brandon, Hinke Huisman‐Siebinga, Shelby Barnett, Paul Wetherell, Pamela Kearns, Brenda Gibson, Nicholas Heaney, Owen Smith, André Baruchel, Arnaud Petit, Andrew Moore, Kayode Ogungbenro, Alwin D. R. Huitema, Gareth J. Veal   +13 more
wiley   +1 more source