Lapatinib is widely used in human oncology; however, dermatological adverse events (DAEs) are common and have been correlated with treatment efficacy. In veterinary medicine, lapatinib use in combination with piroxicam has been shown to be effective in treating canine urothelial carcinoma (UC); however, the incidence and prognostic significance of DAEs
Kosuke Horita +3 more
wiley +1 more source
Concurrent sigmoid colon adenocarcinoma presenting with cutaneous adult T-cell leukemia/lymphoma: a rare case report. [PDF]
Maharati A +7 more
europepmc +1 more source
Cancer heterogeneity explored through immune cell deconvolution of the tumor microenvironment
Abstract Cancer is a highly heterogeneous disease, characterized by significant variability across multiple dimensions. This diversity has been extensively studied from various perspectives. In this study, we aim to examine cancer heterogeneity through the lens of immune cell composition within the tumor microenvironment.
Limin Jiang +4 more
wiley +1 more source
Mycosis Fungoides With Large Cell Lymphoma Transformation: A Report of a Rare Case. [PDF]
Pereira MAM +3 more
europepmc +1 more source
TCF/LEF family transcription factors: Molecular landscape and prognostic scoring in pan‐cancer
This study provides a comprehensive molecular landscape of TCF/LEF family transcription factors across 33 cancer types. We developed a TCF/LEF‐based prognostic score that correlates with immune infiltration, metabolic reprogramming and drug sensitivity, offering a robust transcriptomic signature for predicting patient survival and therapeutic response.
Zhengjun Yang +8 more
wiley +1 more source
Mogamulizumab as Bridge to Thiotepa-Based Allogeneic Haematopoietic Stem Cell Transplantation in Sézary Syndrome: A Single-Centre Experience. [PDF]
Maifredi S +11 more
europepmc +1 more source
Nodular B-Cell Cutaneous Lymphoid Infiltrate With Limited Tissue for Molecular Evaluation: A Case Highlighting Diagnostic Challenges and Management Variability. [PDF]
Naidnur S +4 more
europepmc +1 more source
ABSTRACT Background Gastrointestinal graft‐versus‐host disease (GI GVHD) following hematopoietic stem cell transplant is typically managed with medical therapy, but surgery and angioembolization may be warranted in selected cases with life‐threatening complications.
Gaia Brunetti +12 more
wiley +1 more source
Dose-de-escalated focal radiotherapy for primary cutaneous T-cell lymphoma: a lesion-based retrospective cohort study. [PDF]
Linde P +7 more
europepmc +1 more source

