Results 231 to 240 of about 85,655 (308)

Immune Checkpoint Inhibitors and Immunomodulators for Cancer Immunotherapy: Insights Into Resistance and Therapeutic Strategies

Advanced Science, Volume 13, Issue 25, 4 May 2026.
The schematic diagram illustrates the roles of novel immune checkpoints, immunomodulatory factors, cell death and multimodal technologies in cancer immunotherapy. Abstract Cancer immunotherapy has redefined cancer treatment. However, the molecular and cellular basis of immune evasion and therapeutic resistance remains incompletely understood.
Fangquan Chen, Yang Yu, Xiutao Cai, Junhao Lin, Ruirui Liang, Rui Kang, Daolin Tang, Jiao Liu   +7 more
wiley   +1 more source

Complete remission of relapsed ATXN2L::JAK2 fusion positive anaplastic large cell lymphoma following ruxolitinib monotherapy in a child. [PDF]

NPJ Precis Oncol
Cohen T, Zhou T, Edema U, Pandit-Taskar N, Forlenza C, Price A, Ramaswamy K, Trippett T, Sulis ML, Boelens JJ, Lim MS, Shukla N.   +11 more
europepmc   +1 more source

KDM2B‐Related Neurodevelopmental Disorder A Case‐Series Supporting the CxxC Domain Phenotype With Emphasis on Ocular and Dermatologic Features

American Journal of Medical Genetics Part A, Volume 200, Issue 5, Page 1098-1104, May 2026.
ABSTRACT The KDM2B‐related neurodevelopmental disorder is a recently identified Mendelian disorder of the epigenetic machinery associated with pathogenic variants in KDM2B. Global developmental delay, intellectual disability, congenital anomalies, and systemic manifestations characterize the disorder.
Adriana Gomes, Álvaro Martín‐Rodríguez, Miguel Del Campo, Lynne M. Bird   +3 more
wiley   +1 more source

Primary Cutaneous Rosai-Dorfman Disease With Typical Immunophenotype But Lacking Emperipolesis: A Case Report. [PDF]

Clin Med Insights Case Rep
Al-Soufi L, Marashli A, Younis R, Alkasem AS, Hussein F, Al-Shehabi Z.   +5 more
europepmc   +1 more source

Pigmented Basal Cell Carcinoma Mimicking Melanoma in the Anal Area: A Case Report

Clinical Case Reports, Volume 14, Issue 5, May 2026.
ABSTRACT Early evaluation of persistent perianal lesions is essential even when symptoms appear mild or patients feel embarrassed to seek care. Pigmented basal cell carcinoma in this region is rare and may mimic melanoma clinically. Ongoing histopathological and immunohistochemical assessment is crucial to ensure correct diagnosis and timely surgical ...
Farnaz Araghi, Sareh Salarinejad, Azadeh Rakhshan, Hamideh Moravvej Farshi   +3 more
wiley   +1 more source

First Comprehensive Characterization of Lip Lymphoma: A Population-Based Study.

Acta Haematol
Loap P, Kirova Y.
europepmc   +1 more source

JAK2 Fusions in Adult Patients With Mycosis Fungoides and CD30 Lymphoproliferative Disorders. [PDF]

JAMA Dermatol
Geller S, Liao V, Lavin L, Tang H, Do M, Moy A, Virgen CA, Donnelly L, Pulitzer MP.   +8 more
europepmc   +1 more source

Paradoxical Efficacy With Rare Adverse Events: Sequential ALK Inhibitor Therapy in Lung Adenocarcinoma

Clinical Case Reports, Volume 14, Issue 5, May 2026.
ABSTRACT Anaplastic lymphoma kinase (ALK) inhibitors have markedly improved outcomes in ALK‐positive nonsmall‐cell lung cancer (NSCLC). While their efficacy is well documented, rare or organ‐specific toxicities remain underreported, limiting clinicians' ability to anticipate and manage adverse events during treatment or rechallenge with tyrosine kinase
Kang Xie, Nie Xu
wiley   +1 more source

Delayed Diagnosis of Sézary Syndrome: Lessons From a Psoriasiform Presentation. [PDF]

Clin Case Rep
Neupane S, Neupane A, Khan SA, Kausar H.
europepmc   +1 more source

Synchronous Haemorrhagic Tumors of the Anterior Maxilla and Oropharynx

Clinical Case Reports, Volume 14, Issue 5, May 2026.
Photomicrograph of a low‐power view of partially ulcerated squamous mucosa with underlying vascular proliferation showing anastomosing vascular channels. Hematoxylin and eosin stain. Magnification ×20. ABSTRACT Oral epithelioid angiosarcoma arising in the oral cavity is exceptionally rare.
Brian Maloney, Blessing Obasi, Jason Byrne, Mary Collins, Conor Bowe, Róisín O'Connor   +5 more
wiley   +1 more source