Results 81 to 90 of about 147,528 (279)

Phase 1/2 study of mogamulizumab, a defucosylated anti-CCR4 antibody, in previously treated patients with cutaneous T-cell lymphoma.

Blood, 2015
This phase 1/2 study evaluated the efficacy of mogamulizumab, a defucosylated, humanized, anti-CC chemokine receptor 4 monoclonal antibody, in 41 pretreated patients with cutaneous T-cell lymphoma.
M. Duvic, L. Pinter-Brown, F. Foss, L. Sokol, J. Jorgensen, Pramoda Challagundla, K. Dwyer, Xiaoping Zhang, M. Kurman, R. Ballerini, Li Liu, Youn H. Kim   +11 more
semanticscholar   +1 more source

Cancer therapy‐related cardiotoxicity is associated with distinct alterations of the myocardial lipidome

European Journal of Heart Failure, EarlyView.
Lipidome changes in anthracycline‐induced cardiotoxicity (AIC). Aims Anthracyclines are key components of various chemotherapy regimens, but their clinical utility is limited by severe cardiotoxic side effects. Previous studies have suggested that anthracycline‐induced cardiotoxicity (AIC) may be driven by alterations in myocardial lipid metabolism ...
Vera M. Braun, Anna Foryst‐Ludwig, Ulf Landmesser, István Baczkó, Hendrik Milting, Ulrich Kintscher, Niklas Beyhoff   +6 more
wiley   +1 more source

Streamlining Vorinostat Synthesis: A Chemoenzymatic Continuous Flow Approach

European Journal of Organic Chemistry, EarlyView.
A chemoenzymatic protocol for the synthesis of histone deacetylase inhibitor vorinostat has been established. Immobilized lipase from C. antarctica (imm‐CaLB) allowed the functionalization of suberanoyl acid 1 and further conversion to vorinostat via ion‐exchange resin treatment.
Francesca Annunziata, Lucia Tamborini, Andrea Pinto, Michail S. Christodoulou, Sabrina Dallavalle, Salvatore Princiotto, Martina L. Contente   +6 more
wiley   +1 more source

Interleukin-13 is overexpressed in cutaneous T-cell lymphoma cells and regulates their proliferation.

Blood, 2015
Cutaneous T-cell lymphomas (CTCLs) primarily affect skin and are characterized by proliferation of mature CD4(+) T-helper cells. The pattern of cytokine production in the skin and blood is considered to be of major importance for the pathogenesis of ...
L. Geskin, S. Viragova, D. Stolz, P. Fuschiotti   +3 more
semanticscholar   +1 more source

Clinical Images: Subcutaneous panniculitis‐like T cell lymphoma

Arthritis &Rheumatology, EarlyView.
S Chambers, CN Myrdal, VP Werth
wiley   +1 more source

Safety and Oncologic Outcomes of Endoscopic Endonasal Transcribriform Approach for Locally Advanced Sinonasal Malignancies

Head &Neck, Volume 47, Issue 8, Page 2348-2357, August 2025.
ABSTRACT Introduction The past two decades have seen a paradigm shift in the surgical treatment of sinonasal malignancies, moving from traditional open approaches to minimally invasive endoscopic techniques. Technological advancements have enabled the use of the endoscopic endonasal transcribriform approach (EETA) for tumors involving the anterior ...
Michel Khalaf, Héloïse De Kermadec, Juliette Hershkovitch, Odile Casiraghi, Gabriel Garcia, François Bidault, François‐Régis Ferrand, France Nguyen, Stéphane Temam, Pierre Blanchard, Damien Bresson, Antoine Moya Plana   +11 more
wiley   +1 more source

Multifocal cutaneous non-epitheliotropic B-cell lymphoma in a cat

Journal of Feline Medicine and Surgery Open Reports, 2020
Case summary Skin tumours are the second-most common form of feline cancer after haematopoietic neoplasms and are often malignant. Cutaneous lymphoma is uncommon in cats and can be classified as epitheliotropic (typically of T-cell origin) or non ...
Fausto Quintavalla, Rosanna Di Lecce, Daniele Carlini, Matteo Zanfabro, Anna M Cantoni   +4 more
doaj   +1 more source

Colorectal cancer in a 13‐year‐old with constitutional mismatch repair deficiency and MUTYH heterozygosity

JPGN Reports, EarlyView.
Abstract Constitutional mismatch repair deficiency (CMMRD) is a rare hereditary cancer syndrome resulting from biallelic mutations in DNA mismatch repair (MMR) genes that lead to early‐onset cancers in children, including lymphoma and colorectal cancer (CRC).
Chloe J. Cohan, Caroline Chinchilla Putzeys, Brianna Pruniski, Paul Tran   +3 more
wiley   +1 more source

Primary cutaneous anaplastic large cell lymphoma initially clinically considered to be pyoderma gangrenosum

Medicine Science, 2017
Primary CD30+ anaplastic large cell lymphoma, which is generally seen in adults, is the second most common cutaneous T-cell lymphoma after mycosis fungoides. The lesions are characterized by red-brown plaque or nodules often with ulceration.
Serpil Sener, Nihal Altunisik, Gulbahar Sarac   +2 more
doaj   +1 more source

Topical resiquimod can induce disease regression and enhance T-cell effector functions in cutaneous T-cell lymphoma.

Blood, 2015
Early-stage cutaneous T-cell lymphoma (CTCL) is a skin-limited lymphoma with no cure aside from stem cell transplantation. Twelve patients with stage IA-IIA CTCL were treated in a phase 1 trial of 0.03% and 0.06% topical resiquimod gel, a Toll-like ...
A. Rook, J. Gelfand, M. Wysocka, A. Troxel, B. Benoit, C. Surber, R. Elenitsas, M. Buchanan, Deborah Leahy, R. Watanabe, I. Kirsch, Ellen J. Kim, R. Clark   +12 more
semanticscholar   +1 more source