Results 101 to 110 of about 440,184 (328)

T-cell lymphoma in South America and Europe. [PDF]

, 2012
Peripheral T-cell lymphomas are a group of rare neoplasms originating from clonal proliferation of mature post-thymic lymphocytes with different entities having specific biological characteristics and clinical features.
BELLEI, Monica, Cabrera M. E., Chiattone C. S., Connors J. M., de Souza A. C., FEDERICO, Massimo, Foss F. M., Gabùs R., Horwitz S. M., Liang R., LUMINARI, Stefano, Milone J., Montolo S., Pavlovsky A., PESCE, Emanuela Anna, Pileri S. A., Polliak A., Vose J. M., Zinzani P. L., Zoppegno L., Zucca E.   +20 more
core   +1 more source

Biomaterial Strategies for Targeted Intracellular Delivery to Phagocytes

Advanced Functional Materials, EarlyView.
Phagocytes are essential to a functional immune system, and their behavior defines disease outcomes. Engineered particles offer a strategic opportunity to target phagocytes, harnessing inflammatory modulation in disease. By tuning features like size, shape, and surface, these systems can modulate immune responses and improve targeted treatment for a ...
Kaitlyn E. Woodworth, Neal I. Callaghan, Locke Davenport Huyer   +2 more
wiley   +1 more source

Romidepsin for the Treatment of Peripheral T-Cell Lymphoma

Journal of the Advanced Practitioner in Oncology, 2015
Peripheral T-cell lymphomas (PTCLs) are a rare, heterogeneous group of T-cell– or natural killer cell–derived non-Hodgkin lymphomas. The majority of patients with PTCL experience an aggressive disease course and poor overall survival.
Lisa Barbarotta, K. Hurley
semanticscholar   +2 more sources

Conformity and controversies in the diagnosis, staging and follow-up evaluation of canine nodal lymphoma: a systematic review of the last 15 years of published literature [PDF]

, 2016
Diagnostic methods used in the initial and post-treatment evaluation of canine lymphoma are heterogeneous and can vary within countries and institutions. Accurate reporting of clinical stage and response assessment is crucial in determining the treatment
D. Stefanello, E. Morello, G. A. Polton, G. Lubas, I. Grant, J. Henriques, L. Marconato, M. Dacasto, null null, O. A. Garden, S. Comazzi, S. Sabattini, T. Hendrickx   +12 more
core   +1 more source

Belinostat in Patients With Relapsed or Refractory Peripheral T-Cell Lymphoma: Results of the Pivotal Phase II BELIEF (CLN-19) Study.

Journal of Clinical Oncology, 2015
PURPOSE Peripheral T-cell lymphomas (PTCLs) represent a diverse group of non-Hodgkin lymphomas with a poor prognosis and no accepted standard of care for patients with relapsed or refractory disease.
O. O’Connor, S. Horwitz, T. Masszi, A. van Hoof, P. Brown, J. Doorduijn, G. Hess, W. Jurczak, P. Knoblauch, S. Chawla, G. Bhat, M. Choi, J. Walewski, K. Savage, F. Foss, L. F. Allen, A. Shustov   +16 more
semanticscholar   +1 more source

CD30 expression in peripheral T-cell lymphomas

Haematologica, 2013
CD30 antigen is a trans-membrane glycoprotein belonging to the tumor necrosis factor receptor superfamily.[1][1] Upon stimulation, CD30 exerts pleiotropic effects on cell growth and survival, which largely depend on the NF-κB pathway activation.[2][2] In normal or inflamed tissues, CD30 ...
SABATTINI, ELENA, M. Pizzi, TABANELLI, VALENTINA, BALDIN, PAMELA, C. S. Sacchetti, AGOSTINELLI, CLAUDIO, ZINZANI, PIER LUIGI, PILERI, STEFANO   +7 more
openaire   +4 more sources

Suppressing t(4;11) Acute Leukemia by Lipopolymer Nanoparticle Delivery of siRNA Targeting KMT2A::AFF1 with Enhanced Extrahepatic Delivery

Advanced Healthcare Materials, EarlyView.
This study introduces a new lipopolymer nanoparticle (LPNP) system that efficiently delivers siRNA to leukemia cells. The LPNPs silence the leukemia fusion gene KMT2A::AFF1, induce apoptosis, and decrease leukemia burden in mice. These results demonstrate the potential of LPNPs as a targeted siRNA therapy for acute lymphoblastic leukemia.
Mohammad Nasrullah, Remant KC, Amarnath Praphakar Rajendran, Saba Abbasi Dezfouli, Cezary Kucharski, Xiaoyan Jiang, Spencer B. Gibson, Joseph Brandwein, Olaf Heidenreich, Hasan Uludağ   +9 more
wiley   +1 more source

TCD4pos lymphocytosis in rheumatoid and psoriatic arthritis patients following TNFα blocking agents [PDF]

, 2017
BACKGROUND: Lymphocyte expansion and true lymphocytosis are commonly observed in the everyday clinical practice. The meaning of such phenomenon is often poorly understood so that discrimination between benign and malignant lymphocytosis remains ...
Amodeo, Rachele, Bove, Maurizio, Cox, Maria Christina, D'Amelio, Raffaele, DI ROSA, Roberta, Lagana', Bruno, Markovic, Milica, PICCHIANTI DIAMANTI, Andrea, Pilozzi, Emanuela, Rosado, Maria Manuela, Salemi, Simonetta, Sorgi, Maria Laura   +11 more
core   +1 more source

Angioimmunoblastic T‐cell lymphoma: a rare subtype of peripheral T‐cell lymphoma [PDF]

Clinical Case Reports, 2018
Key Clinical MessageAngioimmunoblastic T‐cell lymphoma (AITL) is a rare form of NHL and usually presents in the late stage due to the atypical laboratory findings. Immunohistochemistry of the lymph node in AITL is characterized by positive CD2, CD3, CD4, CD10, CXCL‐13, PD1 often BCL‐6 and CD20 positive.
Manoj Ponadka Rai, Prabhjot Singh Bedi, Edwin B Marinas, Nazia Naz S. Khan   +3 more
openaire   +3 more sources

Mechanical Interactions Impact the Functions of Immune Cells and Their Application in Immunoengineering

Advanced Therapeutics, EarlyView.
This review covers the mechanical forces experienced by immune cells through cell–cell and cell–extracellular matrix interactions and how these forces influence their receptors and functions. These relationships between forces and cellular functions can be exploited using engineering techniques to modify the physical properties of materials for novel ...
Yu‐Chang Chen, Nghi M. Tran, Kyle H. Vining   +2 more
wiley   +1 more source