Results 11 to 20 of about 14,856,428 (286)

Peripheral T cell lymphoma: clinical utility of romidepsin

Blood and Lymphatic Cancer: Targets and Therapy, 2012
Jasmine Zain, Kathryn SaweyNYU Langone Medical Center, New York, USAIntroduction: Direct therapeutic targets, such as aberrant tumor cell genes and tumor cell markers, have been the focus of cancer treatment for more than 50 years.
Sawey K, Zain J
doaj   +1 more source

The function and origin of the CD4+ T cell in the classical Hodgkin lymphoma microenvironment [PDF]

, 2012
PhDClassical Hodgkin lymphoma (CHL) is a germinal centre B cell malignancy where the bulk of the tumour comprises a non-clonal immune infiltrate enriched for CD4+ T cells.
Greaves, Paul
core   +4 more sources

Using cell-free RNA to identify B- and T-cell clonality for diagnosis and monitoring of B- and T-cell neoplasms. [PDF]

FEBS Open Bio
Using peripheral blood for determining B‐cell or T‐cell clonality is more reliable when we use cell‐free RNA (cfRNA) because cells release blood significantly more RNA than DNA. Next‐generation sequencing (NGS) of cfRNA allows us to evaluate fragment cfRNA and evaluate clonality reliably without the need for prior determination of the specific dominant
Albitar A, Agersborg S, Charifa A, Phull P, Biran N, Vesole D, Parmar H, Pecora A, Ip A, Goy A, Siegel D, Albitar M.   +11 more
europepmc   +2 more sources

Identification and characterization of peripheral T-cell lymphoma-associated SEREX antigens. [PDF]

, 2011
Peripheral T-cell lymphomas (PTCL) are generally less common and pursue a more aggressive clinical course than B-cell lymphomas, with the T-cell phenotype itself being a poor prognostic factor in adult non-Hodgkin lymphoma (NHL).
Graham P. Collins, Liggins, Amanda P., Liggins, AP, Lawrie, Charles H., Banham, Alison H., Pulford, Karen, Pulford Karen, Christopher D. O. Cooper, Cooper Christopher D. O., Christian S. R. Hatton, Hatton, Christian S.R., Cooper, CD, Hatton Christian S. R., Lawrie, CH, Liggins Amanda P., Banham, Alison, Christopher D O Cooper, Hatton, CS, Banham, AH, Collins, GP, Charles H Lawrie, Pulford, K, Amanda P Liggins, Banham Alison H., Karen Pulford, Charles H. Lawrie, Amanda P. Liggins, Collins Graham P., Graham P Collins, Collins, Graham P., Alison H Banham, Christian S R Hatton, Lawrie Charles H., Cooper, Christopher D.O., Alison H. Banham   +34 more
core   +2 more sources

Peripheral T-cell lymphoma

Blood, 2011
AbstractPeripheral T-cell lymphomas (PTCLs) are a heterogeneous group of clinically aggressive diseases associated with poor outcome. Studies that focus specifically on PTCL are emerging, with the ultimate goal of improved understanding of disease biology and the development of more effective therapies.
Foss F. M., ZINZANI, PIER LUIGI, Vose J. M. s, Gascoyne R. D., Rosen S. T., Tobinai K.   +5 more
openaire   +4 more sources

Nodular lymphocyte predominant hodgkin lymphoma and T cell/histiocyte rich large B cell lymphoma : endpoints of a spectrum of one disease? [PDF]

, 2013
In contrast to the commonly indolent clinical behavior of nodular lymphocyte predominant Hodgkin lymphoma (NLPHL), T cell/histiocyte rich large B cell lymphoma (THRLBCL) is frequently diagnosed in advanced clinical stages and has a poor prognosis ...
Benjamin Rengstl, Sebastian Newrzela, Randy Gascoyne, Xavier Sagaert (482298), Xavier Sagaert, Hartmann, Sylvia, Martin-Leo Hansmann, Claudia Döring, Küppers, Ralf, Chris de Wolf-Peeters, Fabio Facchetti, Ralf Küppers, Fabio Facchetti (376587), Sylvia Hartmann, Rengstl, Benjamin, Hansmann, Martin-Leo, Christian Steidl, Sagaert, Xavier, Martin-Leo Hansmann (260067), Tousseyn, Thomas, Christian Steidl (482300), Ralf Küppers (260072), Thomas Tousseyn (482297), Chris de Wolf-Peeters (482299), Steidl, Christian, Claudia Döring (474984), Ponzoni, Maurilio, Randy Gascoyne (482301), Jakobus, Christina, Wolf-Peeters, Chris de, Benjamin Rengstl (482295), Sebastian Newrzela (482296), Gascoyne, Randy, Maurilio Ponzoni (126480), Döring, Claudia, Thomas Tousseyn, Christina Jakobus (482294), Christina Jakobus, Facchetti, Fabio, Sylvia Hartmann (260069), Newrzela, Sebastian, Maurilio Ponzoni   +41 more
core   +2 more sources

CD30-positive peripheral T-cell lymphomas share molecular and phenotypic features

Haematologica, 2013
Peripheral T-cell lymphoma, not otherwise specified is a heterogeneous group of aggressive neoplasms with indistinct borders. By gene expression profiling we previously reported unsupervised clusters of peripheral T-cell lymphomas, not otherwise ...
Bettina Bisig, Aurélien de Reyniès, Christophe Bonnet, Pierre Sujobert, David S. Rickman, Teresa Marafioti, Georges Delsol, Laurence Lamant, Philippe Gaulard, Laurence de Leval   +9 more
doaj   +1 more source

Peripheral T cell lymphoma in Asia [PDF]

International Journal of Hematology, 2014
Peripheral T-cell lymphomas (PTCLs) comprise a heterogeneous group of mature T- and NK-cell neoplasms, the incidence of which is higher in Asian countries than in Western countries. Although its etiology is mainly unknown, several risk factors (such as genetic factors, abnormal immunity, environmental factors, and infectious causes) have been proposed.
Sanghui, Park, Young Hyeh, Ko
openaire   +2 more sources

Gene expression signatures delineate biological and prognostic subgroups in peripheral T-cell lymphoma

, 2014
Peripheral T-cell lymphoma (PTCL) encompasses a heterogeneous group of neoplasms with generally poor clinical outcome. Currently 50% of PTCL cases are not classifiable: PTCL-not otherwise specified (NOS).
Connors, J.M., Wilcox, R.A., Staudt, L.M., Rimsza, L.M., Rosenwald, A., Smith, L., the International Peripheral T-cell Lymphoma, Project, Gascoyne, R.D., Iqbal, J., Braziel, R.M., Lim, S.T., Au, W.Y., Wang, C., Geissinger, E., Gaulard, P., Tan, S.Y., Nakamura, S., Vose, J., Seto, M., Weisenburger, D.D., Delabie, J., Lymphoma Leukemia Molecular Profiling, Project, Jaffe, E.S., Cook, J.R., Guo, S., Armitage, J., Martinez, A., Berger, F., Chan, W.C., Greiner, T.C., Tubbs, R.R., Campo, E., Pileri, S.A., Wright, G., Teh, B.T., Ott, G., Piccaluga, P.P., de Leval, L.   +37 more
core   +2 more sources

The impact of molecular alterations and the immune microenvironment on the natural history of Follicular Lymphoma including transformation to Diffuse Large B cell Lymphoma [PDF]

, 2009
PhDThe natural history of follicular lymphoma is heterogeneous with numerous relapses and remissions over many years. A substantial number of patients suffer an aggressive disease course with death due to disease within 5 years of diagnosis.
Lee, Abigail Mary
core   +4 more sources