Results 211 to 220 of about 440,184 (328)
Abstract Objectives Despite advances in the management of ambulatory paediatric ulcerative colitis (UC), challenges remain as many patients are refractory to therapy and some require colectomy. The aim of these guidelines is to provide an update on optimal care for UC through detailed recommendations and practice points. Methods These guidelines are an
Eytan Wine+24 more
wiley +1 more source
Isolated Central Nervous System Presentation of Early T-Cell Precursor Acute Lymphoblastic Leukemia/Lymphoma: A Rare Case of Exclusive Brain Involvement. [PDF]
Swart VO, Zoghi B.
europepmc +1 more source
Belinostat for the treatment of relapsed or refractory peripheral T-cell lymphoma
P. Campbell, Christan Thomas
semanticscholar +1 more source
ABSTRACT Hepatitis C virus (HCV) infection is associated with an increased risk of cardiovascular disease (CVD); however, the impact of interferon (IFN)‐based therapy on cardiovascular outcomes remains unclear. This nationwide cohort study included 7411 patients with HCV from The Taiwanese Chronic Hepatitis C Cohort registry who received IFN‐based ...
Ping‐Jen Hu+42 more
wiley +1 more source
Diagnosis of Secondary Vitreoretinal Lymphoma With Neurosurgical Stereotactic Biopsy: A Multimodal Diagnostic and Imaging Approach. [PDF]
Sheth N+4 more
europepmc +1 more source
Pooled biomarker analysis of the association of baseline T regulatory cells with response and T-cell recovery profiles with blinatumomab treatment. [PDF]
Katlinskaya Y+7 more
europepmc +1 more source
Cell Apoptosis and Glucocorticoid‐Induced Osteonecrosis
The review identifies glucocorticoid‐induced osteocyte/osteoblast apoptosis as central to femoral head osteonecrosis (GION), mediated through STAT1‐caspase‐3, PI3K/Akt, Wnt/β‐catenin, and oxidative stress pathways. Emerging therapies targeting these pathways (e.g., HIF‐1α stabilization, AMPK activation, and exosome‐mediated miRNA delivery) show ...
Xiumei Tang+7 more
wiley +1 more source
ABSTRACT Neuropsychiatric disorders present a multifaceted challenge, characterized by cognitive, social, and motor impairments with manifold underlying mechanisms. Recent attention has turned to epigenetic mechanisms, particularly histone lysine methyltransferases (HKMTs), such as G9a, in understanding fundamental pathogenesis.
Malak Hajar+4 more
wiley +1 more source