Results 61 to 70 of about 440,184 (328)
Extreme Peripheral Blood Plasmacytosis Mimicking Plasma Cell Leukemia as a Presenting Feature of Angioimmunoblastic T-Cell Lymphoma (AITL). [PDF]
, 2019 Angioimmunoblastic T-cell lymphoma (AITL) is one of four major subtypes of nodal peripheral T cell lymphoma, characterized by its cell of origin, the follicular helper T-cell (TFH).
Alpdogan, Onder +7 more
core +1 more source
Development of chidamide for peripheral T-cell lymphoma, the first orphan drug approved in China.
Intractable & Rare Diseases Research, 2016 Peripheral T-cell lymphoma (PTCL) is a set of rare and highly heterogeneous group of mature T- and NK-cell neoplasms associated with poor outcomes and lack of standard and effective therapies.
Xianping Lu +4 more
semanticscholar +1 more source
Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia
FEBS Letters, EarlyView.This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley +1 more source
Indian Journal of Pathology and Microbiology, 2012 Adult T cell lymphoma/leukemia is a peripheral T-cell neoplasm caused by human T-cell lymphotrophic virus-1, affects mostly adults with systemic involvement and poor prognosis. Diagnosis of adult T-Cell leukemia/Lymphoma is challenging.
Faiq Ahmed +3 more
doaj +1 more source
Culturing adequate CAR-T cells from less peripheral blood to treat B-cell malignancies
Cancer Biology & Medicine, 2021 Objective: Chimeric antigen receptor-modified T (CAR-T) cells have shown impressive results against relapsed/refractory B cell malignancies. However, the traditional manufacture of CAR-T cells requires leukapheresis to isolate large amounts of peripheral
Lu Han +11 more
doaj +1 more source
Az érett T-sejtes lymphomák funkcionális patogenezise = Functional pathogenesis of mature T-cell lymphomas [PDF]
, 2008 A világon az elsők között állapítottuk meg, hogy az angioimmunoblastos T-sejtes lymphoma daganatsejtjei az aktivált follicularis B helper T-sejtek (TFH) immunfenotípusát mutatják.
Bagdi, Enikő, Krenács, László
core
Deciphering the role of Epstein-Barr virus in the pathogenesis of T and NK cell lymphoproliferations [PDF]
, 2011 Epstein-Barr virus (EBV) is a highly successful herpesvirus, colonizing more than 90% of the adult human population worldwide, although it is also associated with various malignant diseases.
Fox, Christopher P +2 more
core +2 more sources
Molecular genetics of peripheral T-cell lymphomas [PDF]
International Journal of Hematology, 2014 Peripheral T-cell lymphomas (PTCL) are rare neoplasms that in most instances respond poorly to conventional chemotherapies. Four varieties--PTCL not otherwise specified (NOS), angioimmunoblastic T-cell lymphoma (AITL), ALK+ anaplastic T-cell lymphoma (ALCL), and ALK- ALCL--account for about 60 % of them. Their classification is difficult because of the
Piccaluga, Pier Paolo +2 more
openaire +4 more sources
FEBS Letters, EarlyView.In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley +1 more source
Case Reports in Medicine, 2015 Background. Extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue (MALT) is a well-characterized entity that may share clinical and morphological findings with other low-grade non-Hodgkin’s lymphomas.
Riad Akoum +2 more
doaj +1 more source